Highly enantioselective construction of tertiary thioethers and alcohols via phosphine-catalyzed asymmetric ?-addition reactions of 5H-thiazol-4-ones and 5H-oxazol-4-ones: scope and mechanistic understandings

• Main Authors: Wang, T, Yu, Z, Hoon, D.L, Huang, K.-W, Lan, Y, Lu, Y
• Other Authors: CHEMISTRY
• Format: Article
• Published: Royal Society of Chemistry 2020
• Subjects: Addition reactions; Catalysis; Enantioselectivity; Hydrogen bonds; Stereochemistry; Asymmetric induction; Bi-functional; Chiral centers; DFT calculation; Donor molecules; Enantioselective; Enantioselective construction; Hydrogen bonding interactions; Phosphorus compounds
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175496
• Institution: National University of Singapore

10.1039/c5sc01614b