Identification of new susceptibility loci for IgA nephropathy in Han Chinese

• Main Authors: Li M., Foo J.-N., Wang J.-Q., Low H.-Q., Tang X.-Q., Toh K.-Y., Yin P.-R., Khor C.-C., Goh Y.-F., Irwan I.D., Xu R.-C., Andiappan A.K., Bei J.-X., Rotzschke O., Chen M.-H., Cheng C.-Y., Sun L.-D., Jiang G.-R., Wong T.-Y., Lin H.-L., Aung T., Liao Y.-H., Saw S.-M., Ye K., Ebstein R.P., Chen Q.-K., Shi W., Chew S.-H., Chen J., Zhang F.-R., Li S.-P., Xu G., Tai E.S., Wang L., Chen N., Zhang X.-J., Zeng Y.-X., Zhang H., Liu Z.-H., Yu X.-Q., Liu J.-J.
• Other Authors: MICROBIOLOGY AND IMMUNOLOGY
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: messenger RNA; 1-aminocyclopropanecarboxylate synthase; CD11b antigen; deficiens protein; early growth response factor; glycoprotein p 15095; heat shock protein; ITGAM protein, human; KLF10 protein, human; kruppel like factor; leukocyte antigen; lyase; ODF1 protein, human; sialyltransferase; ST6GAL1 protein, human; blood; cell organelle; disease prevalence; ethnic group; gene expression; genetic variation; geographical variation; immune response; risk factor; signaling; ACCS gene; Article; blood cell; controlled study; DEFA gene; female; gene; gene cluster; gene frequency; gene identification; gene linkage disequilibrium; gene locus; genetic association; genetic susceptibility; genetic variability; Han Chinese; HLA system; human; immunoglobulin A nephropathy; ITGAX ITGAM gene; major clinical study; major histocompatibility complex; male; ODF1 KLF10 gene; quantitative trait locus; ST6GAL1 gene; validation study; adult; Asian continental ancestry group; case control study; China; genetic predisposition; genetics; genome-wide association study; middle aged; odds ratio; single nucleotide polymorphism; young adult; Adult; Antigens, CD; Antigens, CD11b; Antigens, CD11c; Asian Continental Ancestry Group; Case-Control Studies; DEFICIENS Protein; Early Growth Response Transcription Factors; Female; Genetic Predisposition to Disease; Genome-Wide Association Study; Glomerulonephritis, IGA; Heat-Shock Proteins; Humans; Kruppel-Like Transcription Factors; Lyases; Male; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Sialyltransferases; Young Adult
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175509
• Institution: National University of Singapore

10.1038/ncomms8270