Identification of new susceptibility loci for IgA nephropathy in Han Chinese

10.1038/ncomms8270

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Main Authors:	Li M., Foo J.-N., Wang J.-Q., Low H.-Q., Tang X.-Q., Toh K.-Y., Yin P.-R., Khor C.-C., Goh Y.-F., Irwan I.D., Xu R.-C., Andiappan A.K., Bei J.-X., Rotzschke O., Chen M.-H., Cheng C.-Y., Sun L.-D., Jiang G.-R., Wong T.-Y., Lin H.-L., Aung T., Liao Y.-H., Saw S.-M., Ye K., Ebstein R.P., Chen Q.-K., Shi W., Chew S.-H., Chen J., Zhang F.-R., Li S.-P., Xu G., Tai E.S., Wang L., Chen N., Zhang X.-J., Zeng Y.-X., Zhang H., Liu Z.-H., Yu X.-Q., Liu J.-J.
Other Authors:	MICROBIOLOGY AND IMMUNOLOGY
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	messenger RNA 1-aminocyclopropanecarboxylate synthase CD11b antigen deficiens protein early growth response factor glycoprotein p 15095 heat shock protein ITGAM protein, human KLF10 protein, human kruppel like factor leukocyte antigen lyase ODF1 protein, human sialyltransferase ST6GAL1 protein, human blood cell organelle disease prevalence ethnic group gene expression genetic variation geographical variation immune response risk factor signaling ACCS gene Article blood cell controlled study DEFA gene female gene gene cluster gene frequency gene identification gene linkage disequilibrium gene locus genetic association genetic susceptibility genetic variability Han Chinese HLA system human immunoglobulin A nephropathy ITGAX ITGAM gene major clinical study major histocompatibility complex male ODF1 KLF10 gene quantitative trait locus ST6GAL1 gene validation study adult Asian continental ancestry group case control study China genetic predisposition genetics genome-wide association study middle aged odds ratio single nucleotide polymorphism young adult Adult Antigens, CD Antigens, CD11b Antigens, CD11c Asian Continental Ancestry Group Case-Control Studies DEFICIENS Protein Early Growth Response Transcription Factors Female Genetic Predisposition to Disease Genome-Wide Association Study Glomerulonephritis, IGA Heat-Shock Proteins Humans Kruppel-Like Transcription Factors Lyases Male Middle Aged Odds Ratio Polymorphism, Single Nucleotide Sialyltransferases Young Adult
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/175509
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1755092024-05-08T09:52:20Z Identification of new susceptibility loci for IgA nephropathy in Han Chinese Li M. Foo J.-N. Wang J.-Q. Low H.-Q. Tang X.-Q. Toh K.-Y. Yin P.-R. Khor C.-C. Goh Y.-F. Irwan I.D. Xu R.-C. Andiappan A.K. Bei J.-X. Rotzschke O. Chen M.-H. Cheng C.-Y. Sun L.-D. Jiang G.-R. Wong T.-Y. Lin H.-L. Aung T. Liao Y.-H. Saw S.-M. Ye K. Ebstein R.P. Chen Q.-K. Shi W. Chew S.-H. Chen J. Zhang F.-R. Li S.-P. Xu G. Tai E.S. Wang L. Chen N. Zhang X.-J. Zeng Y.-X. Zhang H. Liu Z.-H. Yu X.-Q. Liu J.-J. MICROBIOLOGY AND IMMUNOLOGY DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL) CANCER SCIENCE INSTITUTE OF SINGAPORE DUKE-NUS MEDICAL SCHOOL OPHTHALMOLOGY SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH MEDICINE messenger RNA 1-aminocyclopropanecarboxylate synthase CD11b antigen deficiens protein early growth response factor glycoprotein p 15095 heat shock protein ITGAM protein, human KLF10 protein, human kruppel like factor leukocyte antigen lyase ODF1 protein, human sialyltransferase ST6GAL1 protein, human blood cell organelle disease prevalence ethnic group gene expression genetic variation geographical variation immune response risk factor signaling ACCS gene Article blood cell controlled study DEFA gene female gene gene cluster gene expression gene frequency gene identification gene linkage disequilibrium gene locus genetic association genetic susceptibility genetic variability Han Chinese HLA system human immunoglobulin A nephropathy ITGAX ITGAM gene major clinical study major histocompatibility complex male ODF1 KLF10 gene quantitative trait locus ST6GAL1 gene validation study adult Asian continental ancestry group case control study China genetic predisposition genetics genome-wide association study immunoglobulin A nephropathy middle aged odds ratio single nucleotide polymorphism young adult China Adult Antigens, CD Antigens, CD11b Antigens, CD11c Asian Continental Ancestry Group Case-Control Studies China DEFICIENS Protein Early Growth Response Transcription Factors Female Genetic Predisposition to Disease Genome-Wide Association Study Glomerulonephritis, IGA Heat-Shock Proteins Humans Kruppel-Like Transcription Factors Lyases Male Middle Aged Odds Ratio Polymorphism, Single Nucleotide Sialyltransferases Young Adult 10.1038/ncomms8270 Nature Communications 6 7270 2020-09-10T01:56:36Z 2020-09-10T01:56:36Z 2015 Article Li M., Foo J.-N., Wang J.-Q., Low H.-Q., Tang X.-Q., Toh K.-Y., Yin P.-R., Khor C.-C., Goh Y.-F., Irwan I.D., Xu R.-C., Andiappan A.K., Bei J.-X., Rotzschke O., Chen M.-H., Cheng C.-Y., Sun L.-D., Jiang G.-R., Wong T.-Y., Lin H.-L., Aung T., Liao Y.-H., Saw S.-M., Ye K., Ebstein R.P., Chen Q.-K., Shi W., Chew S.-H., Chen J., Zhang F.-R., Li S.-P., Xu G., Tai E.S., Wang L., Chen N., Zhang X.-J., Zeng Y.-X., Zhang H., Liu Z.-H., Yu X.-Q., Liu J.-J. (2015). Identification of new susceptibility loci for IgA nephropathy in Han Chinese. Nature Communications 6 : 7270. ScholarBank@NUS Repository. https://doi.org/10.1038/ncomms8270 20411723 https://scholarbank.nus.edu.sg/handle/10635/175509 Nature Publishing Group Unpaywall 20200831
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	messenger RNA 1-aminocyclopropanecarboxylate synthase CD11b antigen deficiens protein early growth response factor glycoprotein p 15095 heat shock protein ITGAM protein, human KLF10 protein, human kruppel like factor leukocyte antigen lyase ODF1 protein, human sialyltransferase ST6GAL1 protein, human blood cell organelle disease prevalence ethnic group gene expression genetic variation geographical variation immune response risk factor signaling ACCS gene Article blood cell controlled study DEFA gene female gene gene cluster gene expression gene frequency gene identification gene linkage disequilibrium gene locus genetic association genetic susceptibility genetic variability Han Chinese HLA system human immunoglobulin A nephropathy ITGAX ITGAM gene major clinical study major histocompatibility complex male ODF1 KLF10 gene quantitative trait locus ST6GAL1 gene validation study adult Asian continental ancestry group case control study China genetic predisposition genetics genome-wide association study immunoglobulin A nephropathy middle aged odds ratio single nucleotide polymorphism young adult China Adult Antigens, CD Antigens, CD11b Antigens, CD11c Asian Continental Ancestry Group Case-Control Studies China DEFICIENS Protein Early Growth Response Transcription Factors Female Genetic Predisposition to Disease Genome-Wide Association Study Glomerulonephritis, IGA Heat-Shock Proteins Humans Kruppel-Like Transcription Factors Lyases Male Middle Aged Odds Ratio Polymorphism, Single Nucleotide Sialyltransferases Young Adult
spellingShingle	messenger RNA 1-aminocyclopropanecarboxylate synthase CD11b antigen deficiens protein early growth response factor glycoprotein p 15095 heat shock protein ITGAM protein, human KLF10 protein, human kruppel like factor leukocyte antigen lyase ODF1 protein, human sialyltransferase ST6GAL1 protein, human blood cell organelle disease prevalence ethnic group gene expression genetic variation geographical variation immune response risk factor signaling ACCS gene Article blood cell controlled study DEFA gene female gene gene cluster gene expression gene frequency gene identification gene linkage disequilibrium gene locus genetic association genetic susceptibility genetic variability Han Chinese HLA system human immunoglobulin A nephropathy ITGAX ITGAM gene major clinical study major histocompatibility complex male ODF1 KLF10 gene quantitative trait locus ST6GAL1 gene validation study adult Asian continental ancestry group case control study China genetic predisposition genetics genome-wide association study immunoglobulin A nephropathy middle aged odds ratio single nucleotide polymorphism young adult China Adult Antigens, CD Antigens, CD11b Antigens, CD11c Asian Continental Ancestry Group Case-Control Studies China DEFICIENS Protein Early Growth Response Transcription Factors Female Genetic Predisposition to Disease Genome-Wide Association Study Glomerulonephritis, IGA Heat-Shock Proteins Humans Kruppel-Like Transcription Factors Lyases Male Middle Aged Odds Ratio Polymorphism, Single Nucleotide Sialyltransferases Young Adult Li M. Foo J.-N. Wang J.-Q. Low H.-Q. Tang X.-Q. Toh K.-Y. Yin P.-R. Khor C.-C. Goh Y.-F. Irwan I.D. Xu R.-C. Andiappan A.K. Bei J.-X. Rotzschke O. Chen M.-H. Cheng C.-Y. Sun L.-D. Jiang G.-R. Wong T.-Y. Lin H.-L. Aung T. Liao Y.-H. Saw S.-M. Ye K. Ebstein R.P. Chen Q.-K. Shi W. Chew S.-H. Chen J. Zhang F.-R. Li S.-P. Xu G. Tai E.S. Wang L. Chen N. Zhang X.-J. Zeng Y.-X. Zhang H. Liu Z.-H. Yu X.-Q. Liu J.-J. Identification of new susceptibility loci for IgA nephropathy in Han Chinese
description	10.1038/ncomms8270
author2	MICROBIOLOGY AND IMMUNOLOGY
author_facet	MICROBIOLOGY AND IMMUNOLOGY Li M. Foo J.-N. Wang J.-Q. Low H.-Q. Tang X.-Q. Toh K.-Y. Yin P.-R. Khor C.-C. Goh Y.-F. Irwan I.D. Xu R.-C. Andiappan A.K. Bei J.-X. Rotzschke O. Chen M.-H. Cheng C.-Y. Sun L.-D. Jiang G.-R. Wong T.-Y. Lin H.-L. Aung T. Liao Y.-H. Saw S.-M. Ye K. Ebstein R.P. Chen Q.-K. Shi W. Chew S.-H. Chen J. Zhang F.-R. Li S.-P. Xu G. Tai E.S. Wang L. Chen N. Zhang X.-J. Zeng Y.-X. Zhang H. Liu Z.-H. Yu X.-Q. Liu J.-J.
format	Article
author	Li M. Foo J.-N. Wang J.-Q. Low H.-Q. Tang X.-Q. Toh K.-Y. Yin P.-R. Khor C.-C. Goh Y.-F. Irwan I.D. Xu R.-C. Andiappan A.K. Bei J.-X. Rotzschke O. Chen M.-H. Cheng C.-Y. Sun L.-D. Jiang G.-R. Wong T.-Y. Lin H.-L. Aung T. Liao Y.-H. Saw S.-M. Ye K. Ebstein R.P. Chen Q.-K. Shi W. Chew S.-H. Chen J. Zhang F.-R. Li S.-P. Xu G. Tai E.S. Wang L. Chen N. Zhang X.-J. Zeng Y.-X. Zhang H. Liu Z.-H. Yu X.-Q. Liu J.-J.
author_sort	Li M.
title	Identification of new susceptibility loci for IgA nephropathy in Han Chinese
title_short	Identification of new susceptibility loci for IgA nephropathy in Han Chinese
title_full	Identification of new susceptibility loci for IgA nephropathy in Han Chinese
title_fullStr	Identification of new susceptibility loci for IgA nephropathy in Han Chinese
title_full_unstemmed	Identification of new susceptibility loci for IgA nephropathy in Han Chinese
title_sort	identification of new susceptibility loci for iga nephropathy in han chinese
publisher	Nature Publishing Group
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/175509
_version_	1800914379897569280

Identification of new susceptibility loci for IgA nephropathy in Han Chinese

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