Lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous RET mouse model of human uveal melanoma

10.18632/oncotarget.6326

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Main Authors: Pin, Y.K, Khoo, K, Tham, M, Karwai, T, Hwee, T.C, Puaux, A.-L, Phua, M.L.C, Kato, M, Angeli, V, Abastado, J.-P
Other Authors: MICROBIOLOGY AND IMMUNOLOGY
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Published: Impact Journals LLC 2020
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/175519
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spelling sg-nus-scholar.10635-1755192024-03-27T08:20:17Z Lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous RET mouse model of human uveal melanoma Pin, Y.K Khoo, K Tham, M Karwai, T Hwee, T.C Puaux, A.-L Phua, M.L.C Kato, M Angeli, V Abastado, J.-P MICROBIOLOGY AND IMMUNOLOGY celecoxib dexamethasone plus tobramycin protein kinase B vasculotropin A vasculotropin receptor 1 cyclooxygenase 2 inhibitor protein kinase B protein Ret RET protein, human vascular endothelial growth factor A, mouse vasculotropin A vasculotropin receptor 1 animal cell animal experiment animal model animal tissue Article cancer cell cancer growth cancer inhibition cancer survival carcinogenesis controlled study enzyme phosphorylation female lymph node dissection lymphangiogenesis male metastasis mouse mouse model nonhuman oncological parameters protein expression tumor growth tumor homeostasis tumor microenvironment uvea melanoma adverse effects animal cell motion cell proliferation disease course drug effects genetic predisposition genetics human lymph node dissection melanoma metabolism Neoplasms, Experimental neovascularization (pathology) pathology phenotype phosphorylation secondary time factor transgenic mouse tumor volume Uveal Neoplasms Animals Cell Movement Cell Proliferation Cyclooxygenase 2 Inhibitors Disease Progression Female Genetic Predisposition to Disease Humans Lymph Node Excision Male Melanoma Mice Mice, Transgenic Neoplasms, Experimental Neovascularization, Pathologic Phenotype Phosphorylation Proto-Oncogene Proteins c-akt Proto-Oncogene Proteins c-ret Time Factors Tumor Burden Uveal Neoplasms Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factor Receptor-1 10.18632/oncotarget.6326 Oncotarget 6 42 44806-44818 2020-09-10T01:59:00Z 2020-09-10T01:59:00Z 2015 Article Pin, Y.K, Khoo, K, Tham, M, Karwai, T, Hwee, T.C, Puaux, A.-L, Phua, M.L.C, Kato, M, Angeli, V, Abastado, J.-P (2015). Lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous RET mouse model of human uveal melanoma. Oncotarget 6 (42) : 44806-44818. ScholarBank@NUS Repository. https://doi.org/10.18632/oncotarget.6326 19492553 https://scholarbank.nus.edu.sg/handle/10635/175519 Impact Journals LLC Unpaywall 20200831
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic celecoxib
dexamethasone plus tobramycin
protein kinase B
vasculotropin A
vasculotropin receptor 1
cyclooxygenase 2 inhibitor
protein kinase B
protein Ret
RET protein, human
vascular endothelial growth factor A, mouse
vasculotropin A
vasculotropin receptor 1
animal cell
animal experiment
animal model
animal tissue
Article
cancer cell
cancer growth
cancer inhibition
cancer survival
carcinogenesis
controlled study
enzyme phosphorylation
female
lymph node dissection
lymphangiogenesis
male
metastasis
mouse
mouse model
nonhuman
oncological parameters
protein expression
tumor growth
tumor homeostasis
tumor microenvironment
uvea melanoma
adverse effects
animal
cell motion
cell proliferation
disease course
drug effects
genetic predisposition
genetics
human
lymph node dissection
melanoma
metabolism
Neoplasms, Experimental
neovascularization (pathology)
pathology
phenotype
phosphorylation
secondary
time factor
transgenic mouse
tumor volume
Uveal Neoplasms
Animals
Cell Movement
Cell Proliferation
Cyclooxygenase 2 Inhibitors
Disease Progression
Female
Genetic Predisposition to Disease
Humans
Lymph Node Excision
Male
Melanoma
Mice
Mice, Transgenic
Neoplasms, Experimental
Neovascularization, Pathologic
Phenotype
Phosphorylation
Proto-Oncogene Proteins c-akt
Proto-Oncogene Proteins c-ret
Time Factors
Tumor Burden
Uveal Neoplasms
Vascular Endothelial Growth Factor A
Vascular Endothelial Growth Factor Receptor-1
spellingShingle celecoxib
dexamethasone plus tobramycin
protein kinase B
vasculotropin A
vasculotropin receptor 1
cyclooxygenase 2 inhibitor
protein kinase B
protein Ret
RET protein, human
vascular endothelial growth factor A, mouse
vasculotropin A
vasculotropin receptor 1
animal cell
animal experiment
animal model
animal tissue
Article
cancer cell
cancer growth
cancer inhibition
cancer survival
carcinogenesis
controlled study
enzyme phosphorylation
female
lymph node dissection
lymphangiogenesis
male
metastasis
mouse
mouse model
nonhuman
oncological parameters
protein expression
tumor growth
tumor homeostasis
tumor microenvironment
uvea melanoma
adverse effects
animal
cell motion
cell proliferation
disease course
drug effects
genetic predisposition
genetics
human
lymph node dissection
melanoma
metabolism
Neoplasms, Experimental
neovascularization (pathology)
pathology
phenotype
phosphorylation
secondary
time factor
transgenic mouse
tumor volume
Uveal Neoplasms
Animals
Cell Movement
Cell Proliferation
Cyclooxygenase 2 Inhibitors
Disease Progression
Female
Genetic Predisposition to Disease
Humans
Lymph Node Excision
Male
Melanoma
Mice
Mice, Transgenic
Neoplasms, Experimental
Neovascularization, Pathologic
Phenotype
Phosphorylation
Proto-Oncogene Proteins c-akt
Proto-Oncogene Proteins c-ret
Time Factors
Tumor Burden
Uveal Neoplasms
Vascular Endothelial Growth Factor A
Vascular Endothelial Growth Factor Receptor-1
Pin, Y.K
Khoo, K
Tham, M
Karwai, T
Hwee, T.C
Puaux, A.-L
Phua, M.L.C
Kato, M
Angeli, V
Abastado, J.-P
Lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous RET mouse model of human uveal melanoma
description 10.18632/oncotarget.6326
author2 MICROBIOLOGY AND IMMUNOLOGY
author_facet MICROBIOLOGY AND IMMUNOLOGY
Pin, Y.K
Khoo, K
Tham, M
Karwai, T
Hwee, T.C
Puaux, A.-L
Phua, M.L.C
Kato, M
Angeli, V
Abastado, J.-P
format Article
author Pin, Y.K
Khoo, K
Tham, M
Karwai, T
Hwee, T.C
Puaux, A.-L
Phua, M.L.C
Kato, M
Angeli, V
Abastado, J.-P
author_sort Pin, Y.K
title Lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous RET mouse model of human uveal melanoma
title_short Lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous RET mouse model of human uveal melanoma
title_full Lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous RET mouse model of human uveal melanoma
title_fullStr Lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous RET mouse model of human uveal melanoma
title_full_unstemmed Lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous RET mouse model of human uveal melanoma
title_sort lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous ret mouse model of human uveal melanoma
publisher Impact Journals LLC
publishDate 2020
url https://scholarbank.nus.edu.sg/handle/10635/175519
_version_ 1795301128311668736