Lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous RET mouse model of human uveal melanoma
10.18632/oncotarget.6326
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sg-nus-scholar.10635-1755192024-03-27T08:20:17Z Lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous RET mouse model of human uveal melanoma Pin, Y.K Khoo, K Tham, M Karwai, T Hwee, T.C Puaux, A.-L Phua, M.L.C Kato, M Angeli, V Abastado, J.-P MICROBIOLOGY AND IMMUNOLOGY celecoxib dexamethasone plus tobramycin protein kinase B vasculotropin A vasculotropin receptor 1 cyclooxygenase 2 inhibitor protein kinase B protein Ret RET protein, human vascular endothelial growth factor A, mouse vasculotropin A vasculotropin receptor 1 animal cell animal experiment animal model animal tissue Article cancer cell cancer growth cancer inhibition cancer survival carcinogenesis controlled study enzyme phosphorylation female lymph node dissection lymphangiogenesis male metastasis mouse mouse model nonhuman oncological parameters protein expression tumor growth tumor homeostasis tumor microenvironment uvea melanoma adverse effects animal cell motion cell proliferation disease course drug effects genetic predisposition genetics human lymph node dissection melanoma metabolism Neoplasms, Experimental neovascularization (pathology) pathology phenotype phosphorylation secondary time factor transgenic mouse tumor volume Uveal Neoplasms Animals Cell Movement Cell Proliferation Cyclooxygenase 2 Inhibitors Disease Progression Female Genetic Predisposition to Disease Humans Lymph Node Excision Male Melanoma Mice Mice, Transgenic Neoplasms, Experimental Neovascularization, Pathologic Phenotype Phosphorylation Proto-Oncogene Proteins c-akt Proto-Oncogene Proteins c-ret Time Factors Tumor Burden Uveal Neoplasms Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factor Receptor-1 10.18632/oncotarget.6326 Oncotarget 6 42 44806-44818 2020-09-10T01:59:00Z 2020-09-10T01:59:00Z 2015 Article Pin, Y.K, Khoo, K, Tham, M, Karwai, T, Hwee, T.C, Puaux, A.-L, Phua, M.L.C, Kato, M, Angeli, V, Abastado, J.-P (2015). Lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous RET mouse model of human uveal melanoma. Oncotarget 6 (42) : 44806-44818. ScholarBank@NUS Repository. https://doi.org/10.18632/oncotarget.6326 19492553 https://scholarbank.nus.edu.sg/handle/10635/175519 Impact Journals LLC Unpaywall 20200831 |
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celecoxib dexamethasone plus tobramycin protein kinase B vasculotropin A vasculotropin receptor 1 cyclooxygenase 2 inhibitor protein kinase B protein Ret RET protein, human vascular endothelial growth factor A, mouse vasculotropin A vasculotropin receptor 1 animal cell animal experiment animal model animal tissue Article cancer cell cancer growth cancer inhibition cancer survival carcinogenesis controlled study enzyme phosphorylation female lymph node dissection lymphangiogenesis male metastasis mouse mouse model nonhuman oncological parameters protein expression tumor growth tumor homeostasis tumor microenvironment uvea melanoma adverse effects animal cell motion cell proliferation disease course drug effects genetic predisposition genetics human lymph node dissection melanoma metabolism Neoplasms, Experimental neovascularization (pathology) pathology phenotype phosphorylation secondary time factor transgenic mouse tumor volume Uveal Neoplasms Animals Cell Movement Cell Proliferation Cyclooxygenase 2 Inhibitors Disease Progression Female Genetic Predisposition to Disease Humans Lymph Node Excision Male Melanoma Mice Mice, Transgenic Neoplasms, Experimental Neovascularization, Pathologic Phenotype Phosphorylation Proto-Oncogene Proteins c-akt Proto-Oncogene Proteins c-ret Time Factors Tumor Burden Uveal Neoplasms Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factor Receptor-1 |
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celecoxib dexamethasone plus tobramycin protein kinase B vasculotropin A vasculotropin receptor 1 cyclooxygenase 2 inhibitor protein kinase B protein Ret RET protein, human vascular endothelial growth factor A, mouse vasculotropin A vasculotropin receptor 1 animal cell animal experiment animal model animal tissue Article cancer cell cancer growth cancer inhibition cancer survival carcinogenesis controlled study enzyme phosphorylation female lymph node dissection lymphangiogenesis male metastasis mouse mouse model nonhuman oncological parameters protein expression tumor growth tumor homeostasis tumor microenvironment uvea melanoma adverse effects animal cell motion cell proliferation disease course drug effects genetic predisposition genetics human lymph node dissection melanoma metabolism Neoplasms, Experimental neovascularization (pathology) pathology phenotype phosphorylation secondary time factor transgenic mouse tumor volume Uveal Neoplasms Animals Cell Movement Cell Proliferation Cyclooxygenase 2 Inhibitors Disease Progression Female Genetic Predisposition to Disease Humans Lymph Node Excision Male Melanoma Mice Mice, Transgenic Neoplasms, Experimental Neovascularization, Pathologic Phenotype Phosphorylation Proto-Oncogene Proteins c-akt Proto-Oncogene Proteins c-ret Time Factors Tumor Burden Uveal Neoplasms Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factor Receptor-1 Pin, Y.K Khoo, K Tham, M Karwai, T Hwee, T.C Puaux, A.-L Phua, M.L.C Kato, M Angeli, V Abastado, J.-P Lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous RET mouse model of human uveal melanoma |
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10.18632/oncotarget.6326 |
author2 |
MICROBIOLOGY AND IMMUNOLOGY |
author_facet |
MICROBIOLOGY AND IMMUNOLOGY Pin, Y.K Khoo, K Tham, M Karwai, T Hwee, T.C Puaux, A.-L Phua, M.L.C Kato, M Angeli, V Abastado, J.-P |
format |
Article |
author |
Pin, Y.K Khoo, K Tham, M Karwai, T Hwee, T.C Puaux, A.-L Phua, M.L.C Kato, M Angeli, V Abastado, J.-P |
author_sort |
Pin, Y.K |
title |
Lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous RET mouse model of human uveal melanoma |
title_short |
Lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous RET mouse model of human uveal melanoma |
title_full |
Lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous RET mouse model of human uveal melanoma |
title_fullStr |
Lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous RET mouse model of human uveal melanoma |
title_full_unstemmed |
Lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous RET mouse model of human uveal melanoma |
title_sort |
lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous ret mouse model of human uveal melanoma |
publisher |
Impact Journals LLC |
publishDate |
2020 |
url |
https://scholarbank.nus.edu.sg/handle/10635/175519 |
_version_ |
1795301128311668736 |