APP intracellular domain acts as a transcriptional regulator of miR-663 suppressing neuronal differentiation

• Main Authors: Shu, R, Wong, W, Ma, Q.H, Yang, Z.Z, Zhu, H, Liu, F.J, Wang, P, Ma, J, Yan, S, Polo, J.M, Bernard, C.C.A, Stanton, L.W, Dawe, G.S, Xiao, Z.C
• Other Authors: BIOLOGICAL SCIENCES
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: amyloid precursor protein; cyclin dependent kinase 6; FBXL18 protein; microRNA; microRNA 3648; microRNA 3687; microRNA 663; peptides and proteins; unclassified drug; DNA binding protein; MIRN663 microRNA, human; protein binding; Article; chromatin immunoprecipitation; controlled study; gene expression; human; human cell; microarray analysis; nerve cell differentiation; nervous system development; neural stem cell; priority journal; protein domain; transcription regulation; cell differentiation; cell line; cytology; gene expression regulation; genetics; metabolism; nerve cell; physiology; Primates; Amyloid beta-Protein Precursor; Cell Differentiation; Cell Line; Chromatin Immunoprecipitation; DNA-Binding Proteins; Gene Expression Regulation; Humans; MicroRNAs; Neurons; Protein Binding
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175530
• Institution: National University of Singapore

10.1038/cddis.2015.10