Extended loop region of Hcp1 is critical for the assembly and function of type VI secretion system in Burkholderia pseudomallei

• Main Authors: Lim, Y.T, Jobichen, C, Wong, J, Limmathurotsakul, D, Li, S, Chen, Y, Raida, M, Srinivasan, N, Macary, P.A, Sivaraman, J, Gan, Y.-H
• Other Authors: BIOLOGY (NU)
• Format: Article
• Published: 2020
• Subjects: bacterium antibody; outer membrane protein; protein binding; recombinant protein; type VI secretion system; amino acid sequence; animal; antigen presenting cell; Burkholderia pseudomallei; cell line; chemical structure; chemistry; genetics; human; immunology; macrophage; melioidosis; metabolism; microbiology; molecular genetics; mouse; mutation; physiology; protein conformation; protein domain; protein multimerization; Amino Acid Sequence; Animals; Antibodies, Bacterial; Antigen-Presenting Cells; Bacterial Outer Membrane Proteins; Cell Line; Humans; Macrophages; Melioidosis; Mice; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protein Conformation; Protein Interaction Domains and Motifs; Protein Multimerization; Recombinant Proteins; Type VI Secretion Systems
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175999
• Institution: National University of Singapore

10.1038/srep08235