Mutations in the Plasmodium falciparum cyclic amine resistance locus (PfCARL) confer multidrug resistance

• Main Authors: Lamonte, G, Lim, M.Y.-X, Wree, M, Reimer, C, Nachon, M, Corey, V, Gedeck, P, Plouffe, D, Du, A, Figueroa, N, Yeung, B, Bifani, P, Winzeler, E.A
• Other Authors: MICROBIOLOGY AND IMMUNOLOGY
• Format: Article
• Published: 2020
• Subjects: antimalarial agent; artemisinin; cyclic amine resistance locus protein; gnf 179; gnf 452; imidazolopiperazine derivative; kaf 156; mefloquine; microorganism protein; oxazole 4 carboxymide; puromycin; tyroscherin; unclassified drug; protozoal protein; Article; cell migration; clustered regularly interspaced short palindromic repeat; controlled study; gene mutation; genetic variability; Golgi complex; molecular weight; multidrug resistance; nonhuman; pfcarl gene; Plasmodium falciparum; priority journal; protein localization; protein targeting; drug effects; gene locus; genetic recombination; genetics; mutation; Antimalarials; Drug Resistance, Multiple; Genetic Loci; Mutation; Protozoan Proteins; Recombination, Genetic
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/176127
• Institution: National University of Singapore

10.1128/mBio.00696-16