Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel

10.18632/oncotarget.3443

Saved in:

Bibliographic Details
Main Authors:	Lee, J.H, Kim, C, Sethi, G, Ahn, K.S
Other Authors:	DEPT OF PHARMACOLOGY
Format:	Article
Published:	Impact Journals LLC 2020
Subjects:	brassinin CD31 antigen interleukin 6 Ki 67 antigen paclitaxel phytoalexin PIAS 3 protein inhibitor of activated STAT small interfering RNA STAT3 protein suppressor of cytokine signaling 3 unclassified drug chaperone indole derivative PIAS3 protein, human SOCS3 protein, human STAT3 protein, human suppressor of cytokine signaling thiocarbamic acid derivative animal experiment animal model animal tissue apoptosis Article cancer cell carcinogenesis cell invasion cell proliferation cell viability controlled study down regulation drug cytotoxicity drug sensitization drug structure female gene induction gene product gene silencing human human cell mouse mouse model non small cell lung cancer nonhuman nude mouse protein expression protein induction protein phosphorylation signal transduction tumor growth tumor xenograft animal antagonists and inhibitors drug effects drug screening genetic transfection K-562 cell line male metabolism randomization tumor cell line Animals Cell Line, Tumor Cell Proliferation Humans Indoles K562 Cells Male Mice Mice, Nude Molecular Chaperones Paclitaxel Protein Inhibitors of Activated STAT Random Allocation Signal Transduction STAT3 Transcription Factor Suppressor of Cytokine Signaling 3 Protein Suppressor of Cytokine Signaling Proteins Thiocarbamates Transfection Xenograft Model Antitumor Assays
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/177761
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	National University of Singapore

id	sg-nus-scholar.10635-177761
record_format	dspace
spelling	sg-nus-scholar.10635-1777612020-10-20T13:49:55Z Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel Lee, J.H Kim, C Sethi, G Ahn, K.S DEPT OF PHARMACOLOGY brassinin CD31 antigen interleukin 6 Ki 67 antigen paclitaxel phytoalexin PIAS 3 protein inhibitor of activated STAT small interfering RNA STAT3 protein suppressor of cytokine signaling 3 unclassified drug brassinin chaperone indole derivative paclitaxel PIAS3 protein, human protein inhibitor of activated STAT SOCS3 protein, human STAT3 protein STAT3 protein, human suppressor of cytokine signaling suppressor of cytokine signaling 3 thiocarbamic acid derivative animal experiment animal model animal tissue apoptosis Article cancer cell carcinogenesis cell invasion cell proliferation cell viability controlled study down regulation drug cytotoxicity drug sensitization drug structure female gene induction gene product gene silencing human human cell mouse mouse model non small cell lung cancer nonhuman nude mouse protein expression protein induction protein phosphorylation signal transduction tumor growth tumor xenograft animal antagonists and inhibitors drug effects drug screening genetic transfection K-562 cell line male metabolism randomization signal transduction tumor cell line Animals Cell Line, Tumor Cell Proliferation Humans Indoles K562 Cells Male Mice Mice, Nude Molecular Chaperones Paclitaxel Protein Inhibitors of Activated STAT Random Allocation Signal Transduction STAT3 Transcription Factor Suppressor of Cytokine Signaling 3 Protein Suppressor of Cytokine Signaling Proteins Thiocarbamates Transfection Xenograft Model Antitumor Assays 10.18632/oncotarget.3443 Oncotarget 6 8 6386-6405 2020-10-20T03:16:02Z 2020-10-20T03:16:02Z 2015 Article Lee, J.H, Kim, C, Sethi, G, Ahn, K.S (2015). Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel. Oncotarget 6 (8) : 6386-6405. ScholarBank@NUS Repository. https://doi.org/10.18632/oncotarget.3443 19492553 https://scholarbank.nus.edu.sg/handle/10635/177761 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Impact Journals LLC Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	brassinin CD31 antigen interleukin 6 Ki 67 antigen paclitaxel phytoalexin PIAS 3 protein inhibitor of activated STAT small interfering RNA STAT3 protein suppressor of cytokine signaling 3 unclassified drug brassinin chaperone indole derivative paclitaxel PIAS3 protein, human protein inhibitor of activated STAT SOCS3 protein, human STAT3 protein STAT3 protein, human suppressor of cytokine signaling suppressor of cytokine signaling 3 thiocarbamic acid derivative animal experiment animal model animal tissue apoptosis Article cancer cell carcinogenesis cell invasion cell proliferation cell viability controlled study down regulation drug cytotoxicity drug sensitization drug structure female gene induction gene product gene silencing human human cell mouse mouse model non small cell lung cancer nonhuman nude mouse protein expression protein induction protein phosphorylation signal transduction tumor growth tumor xenograft animal antagonists and inhibitors drug effects drug screening genetic transfection K-562 cell line male metabolism randomization signal transduction tumor cell line Animals Cell Line, Tumor Cell Proliferation Humans Indoles K562 Cells Male Mice Mice, Nude Molecular Chaperones Paclitaxel Protein Inhibitors of Activated STAT Random Allocation Signal Transduction STAT3 Transcription Factor Suppressor of Cytokine Signaling 3 Protein Suppressor of Cytokine Signaling Proteins Thiocarbamates Transfection Xenograft Model Antitumor Assays
spellingShingle	brassinin CD31 antigen interleukin 6 Ki 67 antigen paclitaxel phytoalexin PIAS 3 protein inhibitor of activated STAT small interfering RNA STAT3 protein suppressor of cytokine signaling 3 unclassified drug brassinin chaperone indole derivative paclitaxel PIAS3 protein, human protein inhibitor of activated STAT SOCS3 protein, human STAT3 protein STAT3 protein, human suppressor of cytokine signaling suppressor of cytokine signaling 3 thiocarbamic acid derivative animal experiment animal model animal tissue apoptosis Article cancer cell carcinogenesis cell invasion cell proliferation cell viability controlled study down regulation drug cytotoxicity drug sensitization drug structure female gene induction gene product gene silencing human human cell mouse mouse model non small cell lung cancer nonhuman nude mouse protein expression protein induction protein phosphorylation signal transduction tumor growth tumor xenograft animal antagonists and inhibitors drug effects drug screening genetic transfection K-562 cell line male metabolism randomization signal transduction tumor cell line Animals Cell Line, Tumor Cell Proliferation Humans Indoles K562 Cells Male Mice Mice, Nude Molecular Chaperones Paclitaxel Protein Inhibitors of Activated STAT Random Allocation Signal Transduction STAT3 Transcription Factor Suppressor of Cytokine Signaling 3 Protein Suppressor of Cytokine Signaling Proteins Thiocarbamates Transfection Xenograft Model Antitumor Assays Lee, J.H Kim, C Sethi, G Ahn, K.S Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel
description	10.18632/oncotarget.3443
author2	DEPT OF PHARMACOLOGY
author_facet	DEPT OF PHARMACOLOGY Lee, J.H Kim, C Sethi, G Ahn, K.S
format	Article
author	Lee, J.H Kim, C Sethi, G Ahn, K.S
author_sort	Lee, J.H
title	Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel
title_short	Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel
title_full	Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel
title_fullStr	Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel
title_full_unstemmed	Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel
title_sort	brassinin inhibits stat3 signaling pathway through modulation of pias-3 and socs-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel
publisher	Impact Journals LLC
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/177761
_version_	1681696259646160896

Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel

Similar Items