West Nile virus drug discovery

• Main Authors: Lim, S.P, Shi, P.-Y
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Published: 2020
• Subjects: agmatine; antivirus agent; benzotriazole derivative; castanospermine 6 butyrate; cyclophilin; cyclosporin A; dabigatran; guanosine triphosphate; helicase; Human immunodeficiency virus proteinase inhibitor; inosinate dehydrogenase; ivermectin; luciferase; minocycline; mycophenolic acid; nitd 982; nonstructural protein 3; nonstructural protein 4; nonstructural protein 5; nucleoside analog; peptide hydrolase inhibitor; propionic acid; recombinant antibody; recombinant humanized monoclonal antibody; ribavirin; rivaroxaban; RNA directed RNA polymerase; stress activated protein kinase; unclassified drug; unindexed drug; West Nile vaccine; antiviral activity; biochemistry; blood brain barrier; computer model; conformational transition; crystal structure; cytotoxicity; Dengue virus; DNA methylation; drug screening; endoplasmic reticulum; gene mutation; Hepatitis C virus; high throughput screening; human; IC 50; molecular docking; nonhuman; nuclear magnetic resonance; phase 1 clinical trial (topic); phase 2 clinical trial (topic); review; structure activity relation; virus replication; West Nile fever; West Nile flavivirus; Antibodies, Viral; Antiviral Agents; Clinical Trials as Topic; Drug Discovery; Drug Evaluation, Preclinical; Drug Repositioning; Humans; West Nile virus
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/177778
• Institution: National University of Singapore

10.3390/v5122977