West Nile virus drug discovery

بواسطة Lim, S.P, Shi, P.-Y
منشور في 2020

U18666A, an intra-cellular cholesterol transport inhibitor, inhibits dengue virus entry and replication

بواسطة Poh, M.K., Shui, G., Xie, X., Shi, P.-Y., Wenk, M.R., Gu, F.
منشور في 2014

West nile virus experimental evolution in vivo and the trade-off hypothesis

بواسطة Deardorff E.R., Fitzpatrick K.A., Jerzak G.V.S., Shi P.-Y., Kramer L.D., Ebel G.D.
منشور في 2019

Crystal structure of the Dengue virus methyltransferase bound to a 5?-capped octameric RNA

بواسطة Yap L.J., Luo D., Chung K.Y., Lim S.P., Bodenreider C., Noble C., Shi P.-Y., Lescar J.
منشور في 2019

A Single Amino Acid Substitution in the Core Protein of West Nile Virus Increases Resistance to Acidotropic Compounds

بواسطة Martín-Acebes M.A., Blázquez A.-B., de Oya N.J., Escribano-Romero E., Shi P.-Y., Saiz J.-C.
منشور في 2019

Evaluation of a novel reporter virus neutralization test for serological diagnosis of Zika and Dengue virus infection

بواسطة Shan, C, Ortiz, D.A, Yang, Y, Wong, S.J, Kramer, L.D, Shi, P.-Y, Loeffelholz, M.J, Ren, P
منشور في 2020

The Interface between Methyltransferase and Polymerase of NS5 Is Essential for Flavivirus Replication

بواسطة Li X.-D., Shan C., Deng C.-L., Ye H.-Q., Shi P.-Y., Yuan Z.-M., Gong P., Zhang B.
منشور في 2019

Dengue Therapeutics, Chemoprophylaxis, and Allied Tools: State of the Art and Future Directions

بواسطة Whitehorn J., Yacoub S., Anders K.L., Macareo L.R., Cassetti M.C., Nguyen Van V.C., Shi P.-Y., Wills B., Simmons C.P.
منشور في 2019

Resistance analysis of an antibody that selectively inhibits dengue virus serotype-1

بواسطة Zou, G., Kukkaro, P., Lok, S.-M., Ng, J.K.W., Tan, G.K., Hanson, B.J., Alonso, S., MacAry, P.A., Shi, P.-Y.
منشور في 2016

Therapeutics for Dengue: Recommendations for Design and Conduct of Early-Phase Clinical Trials

بواسطة Simmons C.P., Wolbers M., Nguyen M.N., Whitehorn J., Shi P.Y., Young P., Petric R., Nguyen V.V.C., Farrar J., Wills B.
منشور في 2019

A small molecule fusion inhibitor of dengue virus

بواسطة Poh, M.K., Yip, A., Zhang, S., Ma, N.L., Shi, P.-Y., Schul, W., Wenk, M.R., Smit, J.M., Wilschut, J., Priestle, J.P.
منشور في 2011

Flexibility of NS5 methyltransferase-polymerase linker region is essential for dengue virus replication

بواسطة Zhao Y., Soh T.S., Chan K.W.K., Fung S.S.Y., Swaminathan K., Lim S.P., Shi P.-Y., Huber T., Lescar J., Luo D., Vasudevan S.G.
منشور في 2020

A single amino acid in nonstructural protein NS4B Confers virulence to dengue virus in AG129 mice through enhancement of viral RNA synthesis

بواسطة Grant, D., Tan, G.K., Qing, M., Ng, J.K.W., Yip, A., Zou, G., Xie, X., Yuan, Z.Y., Schreiber, J., Schul, W., Shi, P.-Y., Alonso, S.
منشور في 2016

Partial genetic characterization of West Nile virus strains, New York State, 2000

بواسطة Ebel, G.D, Dupuis II, A.P, Ngo, K, Nicholas, D, Kauffman, E, Jones, S.A, Young, D, Maffei, J, Shi, P.-Y, Bernard, K, Kramer, L.D
منشور في 2020

Molecular basis of dengue virus serotype 2 morphological switch from 29°C to 37°C

بواسطة Lim, X.-N., Shan, C., Marzinek, J.K., Dong, H., Ng, T.S., Ooi, J.S.G., Fibriansah, G., Wang, J., Verma, C.S., Bond, P.J., Shi, P.-Y., Lok, S.-M.
منشور في 2021

2′-O methylation of internal adenosine by flavivirus NS5 methyltransferase

بواسطة Dong, H., Chang, D.C., Hua, M.H.C., Lim, S.P., Chionh, Y.H., Hia, F., Lee, Y.H., Kukkaro, P., Lok, S.-M., Dedon, P.C., Shi, P.-Y.
منشور في 2016

Dengue subgenomic flaviviral RNA disrupts immunity in mosquito salivary glands to increase virus transmission

بواسطة Pompon J., Manuel M., Ng G.K., Wong B., Shan C., Manokaran G., Soto-Acosta R., Bradrick S.S., Ooi E.E., Missé D., Shi P.-Y., Garcia-Blanco M.A.
منشور في 2020

Understanding zika virus stability and developing a chimeric vaccine through functional analysis

بواسطة Xie, X, Yang, Y, Muruato, A.E, Zou, J, Shan, C, Nunes, B.T.D, Medeiros, D.B.A, Vasconcelos, P.F.C, Weaver, S.C, Rossi, S.L, Shi, P.-Y
منشور في 2020

Characterization of a candidate tetravalent vaccine based on 2’-O-methyltransferase mutants

بواسطة Züst R., Li S.-H., Xie X., Velumani S., Chng M., Toh Y.-X., Zou J., Dong H., Shan C., Pang J., Qin C.-F., Newell E.W., Shi P.-Y., Fink K.
منشور في 2019

A novel reporter system for neutralizing and enhancing antibody assay against dengue virus

بواسطة Song, K.-Y, Zhao, H, Jiang, Z.-Y, Li, X.-F, Deng, Y.-Q, Jiang, T, Zhu, S.-Y, Shi, P.-Y, Zhang, B, Zhang, F.-C, Qin, E.-D, Qin, C.-F
منشور في 2020