The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Diabetic Retinopathy

• Main Authors: Chaurasia, S.S, Lim, R.R, Parikh, B.H, Wey, Y.S, Tun, B.B, Wong, T.Y, Luu, C.D, Agrawal, R, Ghosh, A, Mortellaro, A, Rackoczy, E, Mohan, R.R, Barathi, V.A
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2020
• Subjects: cryopyrin; cytokine; glial fibrillary acidic protein; glial fibrillary astrocytic protein, mouse; Ins2 protein, mouse; insulin; Nlrp3 protein, mouse; vascular endothelial growth factor A, mouse; vasculotropin A; animal; diabetic retinopathy; diagnostic imaging; disease model; electroretinography; fluorescence angiography; genetics; human; metabolism; mouse; neovascularization (pathology); optical coherence tomography; pathology; retina; transgenic mouse; Animals; Cytokines; Diabetic Retinopathy; Disease Models, Animal; Electroretinography; Fluorescein Angiography; Glial Fibrillary Acidic Protein; Humans; Insulin; Mice; Mice, Transgenic; Neovascularization, Pathologic; NLR Family, Pyrin Domain-Containing 3 Protein; Retina; Tomography, Optical Coherence; Vascular Endothelial Growth Factor A
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/177828
• Institution: National University of Singapore

10.1038/s41598-018-21198-z