Identification of early indicators of altered metabolism in normal development using a rodent model system

10.1242/dmm.031815

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Bibliographic Details
Main Authors:	Prabakaran, A.D, Karakkat, J.V, Vijayan, R, Chalissery, J, Ibrahim, M.F, Kaimala, S, Adeghate, E.A, Al-Marzouqi, A.H, Ansari, S.A, Mensah-Brown, E, Emerald, B.S
Other Authors:	DEPT OF BIOCHEMISTRY
Format:	Review
Published:	2020
Subjects:	2 aminoadipate aminotransferase 4 carboxyglutamic acid adiponectin bone sialoprotein collagenase 3 DNA (cytosine 5) methyltransferase 1 DNA methyltransferase 3A DNA methyltransferase 3B endothelin 1 gelatinase B genomic DNA glucagon glucose histone deacetylase 1 insulin leptin messenger RNA neutrophil collagenase osteopontin peroxisome proliferator activated receptor gamma phosphatidylinositol 3 kinase potassium channel protein kinase B protein p16 protein p21 protein Patched 1 retinoblastoma binding protein 1 retinoid X receptor alpha RNA 18S transcription factor E2F1 fatty acid methyltransferase animal cell animal experiment animal model animal tissue cell cycle G0 phase cell cycle G1 phase cell proliferation comparative study controlled study DNA methylation embryo female gene expression gene identification glucagon blood level glucose blood level glucose metabolism glucose tolerance test insulin blood level insulin metabolism litter size low birth weight male metabolic disorder metabolic parameters metabolic regulation mRNA expression level nonhuman nucleotide sequence pancreas islet Pi3K/Akt signaling priority journal promoter region protein expression level rat repressor gene Review rodent model upregulation animal birth weight cell cycle DNA microarray gene expression profiling gene expression regulation genetics growth, development and aging metabolism newborn pancreas islet beta cell real time polymerase chain reaction secretion (process) signal transduction skeletal muscle Wistar rat Animals Animals, Newborn Birth Weight Cell Cycle DNA Methylation Fatty Acids Gene Expression Profiling Gene Expression Regulation, Developmental Glucagon Glucose Growth and Development Insulin Insulin-Secreting Cells Metabolism Methyltransferases Models, Animal Muscle, Skeletal Oligonucleotide Array Sequence Analysis Phosphatidylinositol 3-Kinases PPAR gamma Proto-Oncogene Proteins c-akt Rats, Wistar Real-Time Polymerase Chain Reaction Signal Transduction
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/178102
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1781022023-10-31T20:57:31Z Identification of early indicators of altered metabolism in normal development using a rodent model system Prabakaran, A.D Karakkat, J.V Vijayan, R Chalissery, J Ibrahim, M.F Kaimala, S Adeghate, E.A Al-Marzouqi, A.H Ansari, S.A Mensah-Brown, E Emerald, B.S DEPT OF BIOCHEMISTRY 2 aminoadipate aminotransferase 4 carboxyglutamic acid adiponectin bone sialoprotein collagenase 3 DNA (cytosine 5) methyltransferase 1 DNA methyltransferase 3A DNA methyltransferase 3B endothelin 1 gelatinase B genomic DNA glucagon glucose histone deacetylase 1 insulin leptin messenger RNA neutrophil collagenase osteopontin peroxisome proliferator activated receptor gamma phosphatidylinositol 3 kinase potassium channel protein kinase B protein p16 protein p21 protein Patched 1 retinoblastoma binding protein 1 retinoid X receptor alpha RNA 18S transcription factor E2F1 fatty acid glucagon glucose insulin methyltransferase peroxisome proliferator activated receptor gamma phosphatidylinositol 3 kinase protein kinase B animal cell animal experiment animal model animal tissue cell cycle G0 phase cell cycle G1 phase cell proliferation comparative study controlled study DNA methylation embryo female gene expression gene identification glucagon blood level glucose blood level glucose metabolism glucose tolerance test insulin blood level insulin metabolism litter size low birth weight male metabolic disorder metabolic parameters metabolic regulation mRNA expression level nonhuman nucleotide sequence pancreas islet Pi3K/Akt signaling priority journal promoter region protein expression level rat repressor gene Review rodent model upregulation animal birth weight cell cycle DNA microarray gene expression profiling gene expression regulation genetics growth, development and aging metabolism newborn pancreas islet beta cell real time polymerase chain reaction secretion (process) signal transduction skeletal muscle Wistar rat Animals Animals, Newborn Birth Weight Cell Cycle DNA Methylation Fatty Acids Gene Expression Profiling Gene Expression Regulation, Developmental Glucagon Glucose Growth and Development Insulin Insulin-Secreting Cells Metabolism Methyltransferases Models, Animal Muscle, Skeletal Oligonucleotide Array Sequence Analysis Phosphatidylinositol 3-Kinases PPAR gamma Proto-Oncogene Proteins c-akt Rats, Wistar Real-Time Polymerase Chain Reaction Signal Transduction 10.1242/dmm.031815 DMM Disease Models and Mechanisms 11 3 31815 2020-10-20T05:06:22Z 2020-10-20T05:06:22Z 2018 Review Prabakaran, A.D, Karakkat, J.V, Vijayan, R, Chalissery, J, Ibrahim, M.F, Kaimala, S, Adeghate, E.A, Al-Marzouqi, A.H, Ansari, S.A, Mensah-Brown, E, Emerald, B.S (2018). Identification of early indicators of altered metabolism in normal development using a rodent model system. DMM Disease Models and Mechanisms 11 (3) : 31815. ScholarBank@NUS Repository. https://doi.org/10.1242/dmm.031815 17548403 https://scholarbank.nus.edu.sg/handle/10635/178102 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	2 aminoadipate aminotransferase 4 carboxyglutamic acid adiponectin bone sialoprotein collagenase 3 DNA (cytosine 5) methyltransferase 1 DNA methyltransferase 3A DNA methyltransferase 3B endothelin 1 gelatinase B genomic DNA glucagon glucose histone deacetylase 1 insulin leptin messenger RNA neutrophil collagenase osteopontin peroxisome proliferator activated receptor gamma phosphatidylinositol 3 kinase potassium channel protein kinase B protein p16 protein p21 protein Patched 1 retinoblastoma binding protein 1 retinoid X receptor alpha RNA 18S transcription factor E2F1 fatty acid glucagon glucose insulin methyltransferase peroxisome proliferator activated receptor gamma phosphatidylinositol 3 kinase protein kinase B animal cell animal experiment animal model animal tissue cell cycle G0 phase cell cycle G1 phase cell proliferation comparative study controlled study DNA methylation embryo female gene expression gene identification glucagon blood level glucose blood level glucose metabolism glucose tolerance test insulin blood level insulin metabolism litter size low birth weight male metabolic disorder metabolic parameters metabolic regulation mRNA expression level nonhuman nucleotide sequence pancreas islet Pi3K/Akt signaling priority journal promoter region protein expression level rat repressor gene Review rodent model upregulation animal birth weight cell cycle DNA microarray gene expression profiling gene expression regulation genetics growth, development and aging metabolism newborn pancreas islet beta cell real time polymerase chain reaction secretion (process) signal transduction skeletal muscle Wistar rat Animals Animals, Newborn Birth Weight Cell Cycle DNA Methylation Fatty Acids Gene Expression Profiling Gene Expression Regulation, Developmental Glucagon Glucose Growth and Development Insulin Insulin-Secreting Cells Metabolism Methyltransferases Models, Animal Muscle, Skeletal Oligonucleotide Array Sequence Analysis Phosphatidylinositol 3-Kinases PPAR gamma Proto-Oncogene Proteins c-akt Rats, Wistar Real-Time Polymerase Chain Reaction Signal Transduction
spellingShingle	2 aminoadipate aminotransferase 4 carboxyglutamic acid adiponectin bone sialoprotein collagenase 3 DNA (cytosine 5) methyltransferase 1 DNA methyltransferase 3A DNA methyltransferase 3B endothelin 1 gelatinase B genomic DNA glucagon glucose histone deacetylase 1 insulin leptin messenger RNA neutrophil collagenase osteopontin peroxisome proliferator activated receptor gamma phosphatidylinositol 3 kinase potassium channel protein kinase B protein p16 protein p21 protein Patched 1 retinoblastoma binding protein 1 retinoid X receptor alpha RNA 18S transcription factor E2F1 fatty acid glucagon glucose insulin methyltransferase peroxisome proliferator activated receptor gamma phosphatidylinositol 3 kinase protein kinase B animal cell animal experiment animal model animal tissue cell cycle G0 phase cell cycle G1 phase cell proliferation comparative study controlled study DNA methylation embryo female gene expression gene identification glucagon blood level glucose blood level glucose metabolism glucose tolerance test insulin blood level insulin metabolism litter size low birth weight male metabolic disorder metabolic parameters metabolic regulation mRNA expression level nonhuman nucleotide sequence pancreas islet Pi3K/Akt signaling priority journal promoter region protein expression level rat repressor gene Review rodent model upregulation animal birth weight cell cycle DNA microarray gene expression profiling gene expression regulation genetics growth, development and aging metabolism newborn pancreas islet beta cell real time polymerase chain reaction secretion (process) signal transduction skeletal muscle Wistar rat Animals Animals, Newborn Birth Weight Cell Cycle DNA Methylation Fatty Acids Gene Expression Profiling Gene Expression Regulation, Developmental Glucagon Glucose Growth and Development Insulin Insulin-Secreting Cells Metabolism Methyltransferases Models, Animal Muscle, Skeletal Oligonucleotide Array Sequence Analysis Phosphatidylinositol 3-Kinases PPAR gamma Proto-Oncogene Proteins c-akt Rats, Wistar Real-Time Polymerase Chain Reaction Signal Transduction Prabakaran, A.D Karakkat, J.V Vijayan, R Chalissery, J Ibrahim, M.F Kaimala, S Adeghate, E.A Al-Marzouqi, A.H Ansari, S.A Mensah-Brown, E Emerald, B.S Identification of early indicators of altered metabolism in normal development using a rodent model system
description	10.1242/dmm.031815
author2	DEPT OF BIOCHEMISTRY
author_facet	DEPT OF BIOCHEMISTRY Prabakaran, A.D Karakkat, J.V Vijayan, R Chalissery, J Ibrahim, M.F Kaimala, S Adeghate, E.A Al-Marzouqi, A.H Ansari, S.A Mensah-Brown, E Emerald, B.S
format	Review
author	Prabakaran, A.D Karakkat, J.V Vijayan, R Chalissery, J Ibrahim, M.F Kaimala, S Adeghate, E.A Al-Marzouqi, A.H Ansari, S.A Mensah-Brown, E Emerald, B.S
author_sort	Prabakaran, A.D
title	Identification of early indicators of altered metabolism in normal development using a rodent model system
title_short	Identification of early indicators of altered metabolism in normal development using a rodent model system
title_full	Identification of early indicators of altered metabolism in normal development using a rodent model system
title_fullStr	Identification of early indicators of altered metabolism in normal development using a rodent model system
title_full_unstemmed	Identification of early indicators of altered metabolism in normal development using a rodent model system
title_sort	identification of early indicators of altered metabolism in normal development using a rodent model system
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/178102
_version_	1781792281860243456

Identification of early indicators of altered metabolism in normal development using a rodent model system

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