Mycobacterium tuberculosis-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNF?, NF?B, p38 and caspase 8 dependent pathways

10.1186/1742-2094-8-46

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Main Authors:	Green, J.A, Dholakia, S, Janczar, K, Ong, C.W.M, Moores, R, Fry, J, Elkington, P.T, Roncaroli, F, Friedland, J.S
Other Authors:	MEDICINE
Format:	Article
Published:	BMC 2020
Subjects:	caspase 8 gelatinase A immunoglobulin enhancer binding protein mitogen activated protein kinase p38 transcription factor RelA tumor necrosis factor alpha helenalin mitogen activated protein kinase nonsteroid antiinflammatory agent sesquiterpene article brain biopsy central nervous system tuberculosis clinical article controlled study down regulation enzyme inhibition enzyme regulation enzyme release gene expression human human cell human tissue macrophage microglia monocyte Mycobacterium tuberculosis nonhuman chemistry culture medium cytology genetics metabolism microbiology pathogenicity physiology secretion signal transduction Anti-Inflammatory Agents, Non-Steroidal Caspase 8 Culture Media, Conditioned Extracellular Signal-Regulated MAP Kinases Humans Matrix Metalloproteinase 2 Microglia Monocytes NF-kappa B p38 Mitogen-Activated Protein Kinases Sesquiterpenes Signal Transduction Tuberculosis, Central Nervous System Tumor Necrosis Factor-alpha
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/178177
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1781772024-04-18T03:07:51Z Mycobacterium tuberculosis-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNF?, NF?B, p38 and caspase 8 dependent pathways Green, J.A Dholakia, S Janczar, K Ong, C.W.M Moores, R Fry, J Elkington, P.T Roncaroli, F Friedland, J.S MEDICINE caspase 8 gelatinase A immunoglobulin enhancer binding protein mitogen activated protein kinase p38 transcription factor RelA tumor necrosis factor alpha caspase 8 gelatinase A helenalin immunoglobulin enhancer binding protein mitogen activated protein kinase mitogen activated protein kinase p38 nonsteroid antiinflammatory agent sesquiterpene tumor necrosis factor alpha article brain biopsy central nervous system tuberculosis clinical article controlled study down regulation enzyme inhibition enzyme regulation enzyme release gene expression human human cell human tissue macrophage microglia monocyte Mycobacterium tuberculosis nonhuman chemistry culture medium cytology genetics metabolism microbiology microglia Mycobacterium tuberculosis pathogenicity physiology secretion signal transduction Anti-Inflammatory Agents, Non-Steroidal Caspase 8 Culture Media, Conditioned Extracellular Signal-Regulated MAP Kinases Humans Matrix Metalloproteinase 2 Microglia Monocytes Mycobacterium tuberculosis NF-kappa B p38 Mitogen-Activated Protein Kinases Sesquiterpenes Signal Transduction Tuberculosis, Central Nervous System Tumor Necrosis Factor-alpha 10.1186/1742-2094-8-46 Journal of Neuroinflammation 8 46 2020-10-20T08:13:45Z 2020-10-20T08:13:45Z 2011 Article Green, J.A, Dholakia, S, Janczar, K, Ong, C.W.M, Moores, R, Fry, J, Elkington, P.T, Roncaroli, F, Friedland, J.S (2011). Mycobacterium tuberculosis-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNF?, NF?B, p38 and caspase 8 dependent pathways. Journal of Neuroinflammation 8 : 46. ScholarBank@NUS Repository. https://doi.org/10.1186/1742-2094-8-46 1742-2094 https://scholarbank.nus.edu.sg/handle/10635/178177 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ BMC Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	caspase 8 gelatinase A immunoglobulin enhancer binding protein mitogen activated protein kinase p38 transcription factor RelA tumor necrosis factor alpha caspase 8 gelatinase A helenalin immunoglobulin enhancer binding protein mitogen activated protein kinase mitogen activated protein kinase p38 nonsteroid antiinflammatory agent sesquiterpene tumor necrosis factor alpha article brain biopsy central nervous system tuberculosis clinical article controlled study down regulation enzyme inhibition enzyme regulation enzyme release gene expression human human cell human tissue macrophage microglia monocyte Mycobacterium tuberculosis nonhuman chemistry culture medium cytology genetics metabolism microbiology microglia Mycobacterium tuberculosis pathogenicity physiology secretion signal transduction Anti-Inflammatory Agents, Non-Steroidal Caspase 8 Culture Media, Conditioned Extracellular Signal-Regulated MAP Kinases Humans Matrix Metalloproteinase 2 Microglia Monocytes Mycobacterium tuberculosis NF-kappa B p38 Mitogen-Activated Protein Kinases Sesquiterpenes Signal Transduction Tuberculosis, Central Nervous System Tumor Necrosis Factor-alpha
spellingShingle	caspase 8 gelatinase A immunoglobulin enhancer binding protein mitogen activated protein kinase p38 transcription factor RelA tumor necrosis factor alpha caspase 8 gelatinase A helenalin immunoglobulin enhancer binding protein mitogen activated protein kinase mitogen activated protein kinase p38 nonsteroid antiinflammatory agent sesquiterpene tumor necrosis factor alpha article brain biopsy central nervous system tuberculosis clinical article controlled study down regulation enzyme inhibition enzyme regulation enzyme release gene expression human human cell human tissue macrophage microglia monocyte Mycobacterium tuberculosis nonhuman chemistry culture medium cytology genetics metabolism microbiology microglia Mycobacterium tuberculosis pathogenicity physiology secretion signal transduction Anti-Inflammatory Agents, Non-Steroidal Caspase 8 Culture Media, Conditioned Extracellular Signal-Regulated MAP Kinases Humans Matrix Metalloproteinase 2 Microglia Monocytes Mycobacterium tuberculosis NF-kappa B p38 Mitogen-Activated Protein Kinases Sesquiterpenes Signal Transduction Tuberculosis, Central Nervous System Tumor Necrosis Factor-alpha Green, J.A Dholakia, S Janczar, K Ong, C.W.M Moores, R Fry, J Elkington, P.T Roncaroli, F Friedland, J.S Mycobacterium tuberculosis-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNF?, NF?B, p38 and caspase 8 dependent pathways
description	10.1186/1742-2094-8-46
author2	MEDICINE
author_facet	MEDICINE Green, J.A Dholakia, S Janczar, K Ong, C.W.M Moores, R Fry, J Elkington, P.T Roncaroli, F Friedland, J.S
format	Article
author	Green, J.A Dholakia, S Janczar, K Ong, C.W.M Moores, R Fry, J Elkington, P.T Roncaroli, F Friedland, J.S
author_sort	Green, J.A
title	Mycobacterium tuberculosis-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNF?, NF?B, p38 and caspase 8 dependent pathways
title_short	Mycobacterium tuberculosis-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNF?, NF?B, p38 and caspase 8 dependent pathways
title_full	Mycobacterium tuberculosis-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNF?, NF?B, p38 and caspase 8 dependent pathways
title_fullStr	Mycobacterium tuberculosis-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNF?, NF?B, p38 and caspase 8 dependent pathways
title_full_unstemmed	Mycobacterium tuberculosis-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNF?, NF?B, p38 and caspase 8 dependent pathways
title_sort	mycobacterium tuberculosis-infected human monocytes down-regulate microglial mmp-2 secretion in cns tuberculosis via tnf?, nf?b, p38 and caspase 8 dependent pathways
publisher	BMC
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/178177
_version_	1800914480522067968

Mycobacterium tuberculosis-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNF?, NF?B, p38 and caspase 8 dependent pathways

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