The protein kinase CK2 catalytic domain from Plasmodium falciparum: Crystal structure, tyrosine kinase activity and inhibition

• Main Authors: Ruiz-Carrillo, D, Lin, J, El Sahili, A, Wei, M, Sze, S.K, Cheung, P.C.F, Doerig, C, Lescar, J
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: casein kinase II; protein kinase inhibitor; protein tyrosine kinase; amino acid sequence; chemistry; enzyme active site; enzymology; gene expression regulation; genetics; metabolism; molecular model; mutation; phosphorylation; Plasmodium falciparum; X ray crystallography; Amino Acid Sequence; Casein Kinase II; Catalytic Domain; Crystallography, X-Ray; Gene Expression Regulation, Enzymologic; Models, Molecular; Mutation; Phosphorylation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/178413
• Institution: National University of Singapore

10.1038/s41598-018-25738-5