A preliminary study on efficacy of rupatadine for the treatment of acute dengue infection

10.1038/s41598-018-22285-x

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Main Authors: Malavige, G.N, Wijewickrama, A, Fernando, S, Jeewandara, C, Ginneliya, A, Samarasekara, S, Madushanka, P, Punchihewa, C, Paranavitane, S, Idampitiya, D, Wanigatunga, C, Dissanayake, H, Prathapan, S, Gomes, L, Aman, S.A.B, John, A.S, Ogg, G.S
Other Authors: DUKE-NUS MEDICAL SCHOOL
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Published: Nature Publishing Group 2020
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/178426
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spelling sg-nus-scholar.10635-1784262023-08-30T22:11:43Z A preliminary study on efficacy of rupatadine for the treatment of acute dengue infection Malavige, G.N Wijewickrama, A Fernando, S Jeewandara, C Ginneliya, A Samarasekara, S Madushanka, P Punchihewa, C Paranavitane, S Idampitiya, D Wanigatunga, C Dissanayake, H Prathapan, S Gomes, L Aman, S.A.B John, A.S Ogg, G.S DUKE-NUS MEDICAL SCHOOL antiallergic agent antihistaminic agent cyproheptadine histamine H1 receptor antagonist rupatadine acute disease adult animal C57BL mouse dengue Dengue virus disease model double blind procedure drug effect endothelium female human male metabolism mouse pathogenicity preliminary data Sri Lanka thrombocyte treatment outcome umbilical vein endothelial cell Acute Disease Adult Animals Anti-Allergic Agents Blood Platelets Cyproheptadine Dengue Dengue Virus Disease Models, Animal Double-Blind Method Endothelium Female Histamine Antagonists Histamine H1 Antagonists, Non-Sedating Human Umbilical Vein Endothelial Cells Humans Male Mice Mice, Inbred C57BL Preliminary Data Sri Lanka Treatment Outcome 10.1038/s41598-018-22285-x Scientific Reports 8 1 3857 2020-10-20T09:54:52Z 2020-10-20T09:54:52Z 2018 Article Malavige, G.N, Wijewickrama, A, Fernando, S, Jeewandara, C, Ginneliya, A, Samarasekara, S, Madushanka, P, Punchihewa, C, Paranavitane, S, Idampitiya, D, Wanigatunga, C, Dissanayake, H, Prathapan, S, Gomes, L, Aman, S.A.B, John, A.S, Ogg, G.S (2018). A preliminary study on efficacy of rupatadine for the treatment of acute dengue infection. Scientific Reports 8 (1) : 3857. ScholarBank@NUS Repository. https://doi.org/10.1038/s41598-018-22285-x 2045-2322 https://scholarbank.nus.edu.sg/handle/10635/178426 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Nature Publishing Group Unpaywall 20201031
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic antiallergic agent
antihistaminic agent
cyproheptadine
histamine H1 receptor antagonist
rupatadine
acute disease
adult
animal
C57BL mouse
dengue
Dengue virus
disease model
double blind procedure
drug effect
endothelium
female
human
male
metabolism
mouse
pathogenicity
preliminary data
Sri Lanka
thrombocyte
treatment outcome
umbilical vein endothelial cell
Acute Disease
Adult
Animals
Anti-Allergic Agents
Blood Platelets
Cyproheptadine
Dengue
Dengue Virus
Disease Models, Animal
Double-Blind Method
Endothelium
Female
Histamine Antagonists
Histamine H1 Antagonists, Non-Sedating
Human Umbilical Vein Endothelial Cells
Humans
Male
Mice
Mice, Inbred C57BL
Preliminary Data
Sri Lanka
Treatment Outcome
spellingShingle antiallergic agent
antihistaminic agent
cyproheptadine
histamine H1 receptor antagonist
rupatadine
acute disease
adult
animal
C57BL mouse
dengue
Dengue virus
disease model
double blind procedure
drug effect
endothelium
female
human
male
metabolism
mouse
pathogenicity
preliminary data
Sri Lanka
thrombocyte
treatment outcome
umbilical vein endothelial cell
Acute Disease
Adult
Animals
Anti-Allergic Agents
Blood Platelets
Cyproheptadine
Dengue
Dengue Virus
Disease Models, Animal
Double-Blind Method
Endothelium
Female
Histamine Antagonists
Histamine H1 Antagonists, Non-Sedating
Human Umbilical Vein Endothelial Cells
Humans
Male
Mice
Mice, Inbred C57BL
Preliminary Data
Sri Lanka
Treatment Outcome
Malavige, G.N
Wijewickrama, A
Fernando, S
Jeewandara, C
Ginneliya, A
Samarasekara, S
Madushanka, P
Punchihewa, C
Paranavitane, S
Idampitiya, D
Wanigatunga, C
Dissanayake, H
Prathapan, S
Gomes, L
Aman, S.A.B
John, A.S
Ogg, G.S
A preliminary study on efficacy of rupatadine for the treatment of acute dengue infection
description 10.1038/s41598-018-22285-x
author2 DUKE-NUS MEDICAL SCHOOL
author_facet DUKE-NUS MEDICAL SCHOOL
Malavige, G.N
Wijewickrama, A
Fernando, S
Jeewandara, C
Ginneliya, A
Samarasekara, S
Madushanka, P
Punchihewa, C
Paranavitane, S
Idampitiya, D
Wanigatunga, C
Dissanayake, H
Prathapan, S
Gomes, L
Aman, S.A.B
John, A.S
Ogg, G.S
format Article
author Malavige, G.N
Wijewickrama, A
Fernando, S
Jeewandara, C
Ginneliya, A
Samarasekara, S
Madushanka, P
Punchihewa, C
Paranavitane, S
Idampitiya, D
Wanigatunga, C
Dissanayake, H
Prathapan, S
Gomes, L
Aman, S.A.B
John, A.S
Ogg, G.S
author_sort Malavige, G.N
title A preliminary study on efficacy of rupatadine for the treatment of acute dengue infection
title_short A preliminary study on efficacy of rupatadine for the treatment of acute dengue infection
title_full A preliminary study on efficacy of rupatadine for the treatment of acute dengue infection
title_fullStr A preliminary study on efficacy of rupatadine for the treatment of acute dengue infection
title_full_unstemmed A preliminary study on efficacy of rupatadine for the treatment of acute dengue infection
title_sort preliminary study on efficacy of rupatadine for the treatment of acute dengue infection
publisher Nature Publishing Group
publishDate 2020
url https://scholarbank.nus.edu.sg/handle/10635/178426
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