Rap1 deficiency-provoked paracrine dysfunction impairs immunosuppressive potency of mesenchymal stem cells in allograft rejection of heart transplantation

10.1038/s41419-018-0414-3

Saved in:

Bibliographic Details
Main Authors:	Ding, Y, Liang, X, Zhang, Y, Yi, L, Shum, H.C, Chen, Q, Chan, B.P, Fan, H, Liu, Z, Tergaonkar, V, Qi, Z, Tse, H.-F, Lian, Q
Other Authors:	PATHOLOGY
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	immunoglobulin enhancer binding protein Rap1 protein rapamycin acute graft rejection animal experiment Article cell encapsulation controlled study cytokine production cytokine release down regulation gene construct graft recipient graft survival heart transplantation immunomodulation in vitro study mesenchymal stem cell mixed lymphocyte reaction mouse nonhuman paracrine signaling priority journal regulatory mechanism adverse event allograft animal Bagg albino mouse C57BL mouse cell culture cell proliferation genetics graft rejection knockout mouse metabolism physiology Western blotting Allografts Animals Blotting, Western Cell Proliferation Cells, Cultured Graft Rejection Heart Transplantation Mesenchymal Stem Cells Mice Mice, Inbred BALB C Mice, Inbred C57BL Mice, Knockout NF-kappa B rap1 GTP-Binding Proteins
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/178536
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	National University of Singapore

id	sg-nus-scholar.10635-178536
record_format	dspace
spelling	sg-nus-scholar.10635-1785362024-04-03T07:37:58Z Rap1 deficiency-provoked paracrine dysfunction impairs immunosuppressive potency of mesenchymal stem cells in allograft rejection of heart transplantation Ding, Y Liang, X Zhang, Y Yi, L Shum, H.C Chen, Q Chan, B.P Fan, H Liu, Z Tergaonkar, V Qi, Z Tse, H.-F Lian, Q PATHOLOGY immunoglobulin enhancer binding protein Rap1 protein rapamycin immunoglobulin enhancer binding protein Rap1 protein acute graft rejection animal experiment Article cell encapsulation controlled study cytokine production cytokine release down regulation gene construct graft recipient graft survival heart transplantation immunomodulation in vitro study mesenchymal stem cell mixed lymphocyte reaction mouse nonhuman paracrine signaling priority journal regulatory mechanism adverse event allograft animal Bagg albino mouse C57BL mouse cell culture cell proliferation genetics graft rejection heart transplantation knockout mouse mesenchymal stem cell metabolism physiology Western blotting Allografts Animals Blotting, Western Cell Proliferation Cells, Cultured Graft Rejection Heart Transplantation Mesenchymal Stem Cells Mice Mice, Inbred BALB C Mice, Inbred C57BL Mice, Knockout NF-kappa B rap1 GTP-Binding Proteins 10.1038/s41419-018-0414-3 Cell Death and Disease 9 3 386 2020-10-20T10:12:39Z 2020-10-20T10:12:39Z 2018 Article Ding, Y, Liang, X, Zhang, Y, Yi, L, Shum, H.C, Chen, Q, Chan, B.P, Fan, H, Liu, Z, Tergaonkar, V, Qi, Z, Tse, H.-F, Lian, Q (2018). Rap1 deficiency-provoked paracrine dysfunction impairs immunosuppressive potency of mesenchymal stem cells in allograft rejection of heart transplantation. Cell Death and Disease 9 (3) : 386. ScholarBank@NUS Repository. https://doi.org/10.1038/s41419-018-0414-3 2041-4889 https://scholarbank.nus.edu.sg/handle/10635/178536 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Nature Publishing Group Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	immunoglobulin enhancer binding protein Rap1 protein rapamycin immunoglobulin enhancer binding protein Rap1 protein acute graft rejection animal experiment Article cell encapsulation controlled study cytokine production cytokine release down regulation gene construct graft recipient graft survival heart transplantation immunomodulation in vitro study mesenchymal stem cell mixed lymphocyte reaction mouse nonhuman paracrine signaling priority journal regulatory mechanism adverse event allograft animal Bagg albino mouse C57BL mouse cell culture cell proliferation genetics graft rejection heart transplantation knockout mouse mesenchymal stem cell metabolism physiology Western blotting Allografts Animals Blotting, Western Cell Proliferation Cells, Cultured Graft Rejection Heart Transplantation Mesenchymal Stem Cells Mice Mice, Inbred BALB C Mice, Inbred C57BL Mice, Knockout NF-kappa B rap1 GTP-Binding Proteins
spellingShingle	immunoglobulin enhancer binding protein Rap1 protein rapamycin immunoglobulin enhancer binding protein Rap1 protein acute graft rejection animal experiment Article cell encapsulation controlled study cytokine production cytokine release down regulation gene construct graft recipient graft survival heart transplantation immunomodulation in vitro study mesenchymal stem cell mixed lymphocyte reaction mouse nonhuman paracrine signaling priority journal regulatory mechanism adverse event allograft animal Bagg albino mouse C57BL mouse cell culture cell proliferation genetics graft rejection heart transplantation knockout mouse mesenchymal stem cell metabolism physiology Western blotting Allografts Animals Blotting, Western Cell Proliferation Cells, Cultured Graft Rejection Heart Transplantation Mesenchymal Stem Cells Mice Mice, Inbred BALB C Mice, Inbred C57BL Mice, Knockout NF-kappa B rap1 GTP-Binding Proteins Ding, Y Liang, X Zhang, Y Yi, L Shum, H.C Chen, Q Chan, B.P Fan, H Liu, Z Tergaonkar, V Qi, Z Tse, H.-F Lian, Q Rap1 deficiency-provoked paracrine dysfunction impairs immunosuppressive potency of mesenchymal stem cells in allograft rejection of heart transplantation
description	10.1038/s41419-018-0414-3
author2	PATHOLOGY
author_facet	PATHOLOGY Ding, Y Liang, X Zhang, Y Yi, L Shum, H.C Chen, Q Chan, B.P Fan, H Liu, Z Tergaonkar, V Qi, Z Tse, H.-F Lian, Q
format	Article
author	Ding, Y Liang, X Zhang, Y Yi, L Shum, H.C Chen, Q Chan, B.P Fan, H Liu, Z Tergaonkar, V Qi, Z Tse, H.-F Lian, Q
author_sort	Ding, Y
title	Rap1 deficiency-provoked paracrine dysfunction impairs immunosuppressive potency of mesenchymal stem cells in allograft rejection of heart transplantation
title_short	Rap1 deficiency-provoked paracrine dysfunction impairs immunosuppressive potency of mesenchymal stem cells in allograft rejection of heart transplantation
title_full	Rap1 deficiency-provoked paracrine dysfunction impairs immunosuppressive potency of mesenchymal stem cells in allograft rejection of heart transplantation
title_fullStr	Rap1 deficiency-provoked paracrine dysfunction impairs immunosuppressive potency of mesenchymal stem cells in allograft rejection of heart transplantation
title_full_unstemmed	Rap1 deficiency-provoked paracrine dysfunction impairs immunosuppressive potency of mesenchymal stem cells in allograft rejection of heart transplantation
title_sort	rap1 deficiency-provoked paracrine dysfunction impairs immunosuppressive potency of mesenchymal stem cells in allograft rejection of heart transplantation
publisher	Nature Publishing Group
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/178536
_version_	1795374464680067072

Rap1 deficiency-provoked paracrine dysfunction impairs immunosuppressive potency of mesenchymal stem cells in allograft rejection of heart transplantation

Similar Items