Matrix metalloproteinase-9 activity and a downregulated Hedgehog pathway impair blood-brain barrier function in an in vitro model of CNS tuberculosis

10.1038/s41598-017-16250-3

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Main Authors:	Brilha, S, Ong, C.W.M, Weksler, B, Romero, N, Couraud, P.-O, Friedland, J.S
Other Authors:	MEDICINE
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	gelatinase B sonic hedgehog protein blood brain barrier cell culture cell line central nervous system tuberculosis conditioned medium enzyme linked immunosorbent assay genetics human metabolism Mycobacterium tuberculosis pathogenicity physiology signal transduction tight junction Blood-Brain Barrier Cell Line Cells, Cultured Culture Media, Conditioned Enzyme-Linked Immunosorbent Assay Hedgehog Proteins Humans Matrix Metalloproteinase 9 Signal Transduction Tight Junctions Tuberculosis, Central Nervous System
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/178557
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1785572024-04-24T05:50:40Z Matrix metalloproteinase-9 activity and a downregulated Hedgehog pathway impair blood-brain barrier function in an in vitro model of CNS tuberculosis Brilha, S Ong, C.W.M Weksler, B Romero, N Couraud, P.-O Friedland, J.S MEDICINE gelatinase B sonic hedgehog protein blood brain barrier cell culture cell line central nervous system tuberculosis conditioned medium enzyme linked immunosorbent assay genetics human metabolism Mycobacterium tuberculosis pathogenicity physiology signal transduction tight junction Blood-Brain Barrier Cell Line Cells, Cultured Culture Media, Conditioned Enzyme-Linked Immunosorbent Assay Hedgehog Proteins Humans Matrix Metalloproteinase 9 Mycobacterium tuberculosis Signal Transduction Tight Junctions Tuberculosis, Central Nervous System 10.1038/s41598-017-16250-3 Scientific Reports 7 1 16031 2020-10-20T10:18:35Z 2020-10-20T10:18:35Z 2017 Article Brilha, S, Ong, C.W.M, Weksler, B, Romero, N, Couraud, P.-O, Friedland, J.S (2017). Matrix metalloproteinase-9 activity and a downregulated Hedgehog pathway impair blood-brain barrier function in an in vitro model of CNS tuberculosis. Scientific Reports 7 (1) : 16031. ScholarBank@NUS Repository. https://doi.org/10.1038/s41598-017-16250-3 2045-2322 https://scholarbank.nus.edu.sg/handle/10635/178557 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Nature Publishing Group Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	gelatinase B sonic hedgehog protein blood brain barrier cell culture cell line central nervous system tuberculosis conditioned medium enzyme linked immunosorbent assay genetics human metabolism Mycobacterium tuberculosis pathogenicity physiology signal transduction tight junction Blood-Brain Barrier Cell Line Cells, Cultured Culture Media, Conditioned Enzyme-Linked Immunosorbent Assay Hedgehog Proteins Humans Matrix Metalloproteinase 9 Mycobacterium tuberculosis Signal Transduction Tight Junctions Tuberculosis, Central Nervous System
spellingShingle	gelatinase B sonic hedgehog protein blood brain barrier cell culture cell line central nervous system tuberculosis conditioned medium enzyme linked immunosorbent assay genetics human metabolism Mycobacterium tuberculosis pathogenicity physiology signal transduction tight junction Blood-Brain Barrier Cell Line Cells, Cultured Culture Media, Conditioned Enzyme-Linked Immunosorbent Assay Hedgehog Proteins Humans Matrix Metalloproteinase 9 Mycobacterium tuberculosis Signal Transduction Tight Junctions Tuberculosis, Central Nervous System Brilha, S Ong, C.W.M Weksler, B Romero, N Couraud, P.-O Friedland, J.S Matrix metalloproteinase-9 activity and a downregulated Hedgehog pathway impair blood-brain barrier function in an in vitro model of CNS tuberculosis
description	10.1038/s41598-017-16250-3
author2	MEDICINE
author_facet	MEDICINE Brilha, S Ong, C.W.M Weksler, B Romero, N Couraud, P.-O Friedland, J.S
format	Article
author	Brilha, S Ong, C.W.M Weksler, B Romero, N Couraud, P.-O Friedland, J.S
author_sort	Brilha, S
title	Matrix metalloproteinase-9 activity and a downregulated Hedgehog pathway impair blood-brain barrier function in an in vitro model of CNS tuberculosis
title_short	Matrix metalloproteinase-9 activity and a downregulated Hedgehog pathway impair blood-brain barrier function in an in vitro model of CNS tuberculosis
title_full	Matrix metalloproteinase-9 activity and a downregulated Hedgehog pathway impair blood-brain barrier function in an in vitro model of CNS tuberculosis
title_fullStr	Matrix metalloproteinase-9 activity and a downregulated Hedgehog pathway impair blood-brain barrier function in an in vitro model of CNS tuberculosis
title_full_unstemmed	Matrix metalloproteinase-9 activity and a downregulated Hedgehog pathway impair blood-brain barrier function in an in vitro model of CNS tuberculosis
title_sort	matrix metalloproteinase-9 activity and a downregulated hedgehog pathway impair blood-brain barrier function in an in vitro model of cns tuberculosis
publisher	Nature Publishing Group
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/178557
_version_	1800914508889194496

Matrix metalloproteinase-9 activity and a downregulated Hedgehog pathway impair blood-brain barrier function in an in vitro model of CNS tuberculosis

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