The telomere binding protein Pot1 maintains haematopoietic stem cell activity with age
10.1038/s41467-017-00935-4
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Published: |
Nature Publishing Group
2020
|
| Subjects: | |
| Online Access: | https://scholarbank.nus.edu.sg/handle/10635/178570 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Institution: | National University of Singapore |
| id |
sg-nus-scholar.10635-178570 |
|---|---|
| record_format |
dspace |
| spelling |
sg-nus-scholar.10635-1785702024-11-13T19:57:06Z The telomere binding protein Pot1 maintains haematopoietic stem cell activity with age Hosokawa, K MacArthur, B.D Ikushima, Y.M Toyama, H Masuhiro, Y Hanazawa, S Suda, T Arai, F MEDICINE Pot1 protein reactive oxygen metabolite telomere binding protein unclassified drug DNA binding protein POT1 protein, mouse reactive oxygen metabolite age cells and cell components chromosome DNA gene expression protein reactive oxygen species animal cell apoptosis Article cell activity cell aging cell differentiation cell function cell protection cell survival controlled study DNA damage response down regulation ex vivo study gene expression hematopoietic stem cell human human cell microarray analysis mouse nonhuman oxidative phosphorylation protein expression protein function rejuvenation senescence stem cell culture stem cell expansion stem cell self-renewal animal cell aging cell culture DNA damage genetics hematopoietic stem cell metabolism physiology telomere Animals Cells, Cultured Cellular Senescence DNA Damage DNA-Binding Proteins Hematopoietic Stem Cells Humans Mice Reactive Oxygen Species Telomere 10.1038/s41467-017-00935-4 Nature Communications 8 1 804 2020-10-20T10:22:02Z 2020-10-20T10:22:02Z 2017 Article Hosokawa, K, MacArthur, B.D, Ikushima, Y.M, Toyama, H, Masuhiro, Y, Hanazawa, S, Suda, T, Arai, F (2017). The telomere binding protein Pot1 maintains haematopoietic stem cell activity with age. Nature Communications 8 (1) : 804. ScholarBank@NUS Repository. https://doi.org/10.1038/s41467-017-00935-4 2041-1723 https://scholarbank.nus.edu.sg/handle/10635/178570 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Nature Publishing Group Unpaywall 20201031 |
| institution |
National University of Singapore |
| building |
NUS Library |
| continent |
Asia |
| country |
Singapore Singapore |
| content_provider |
NUS Library |
| collection |
ScholarBank@NUS |
| topic |
Pot1 protein reactive oxygen metabolite telomere binding protein unclassified drug DNA binding protein POT1 protein, mouse reactive oxygen metabolite age cells and cell components chromosome DNA gene expression protein reactive oxygen species animal cell apoptosis Article cell activity cell aging cell differentiation cell function cell protection cell survival controlled study DNA damage response down regulation ex vivo study gene expression hematopoietic stem cell human human cell microarray analysis mouse nonhuman oxidative phosphorylation protein expression protein function rejuvenation senescence stem cell culture stem cell expansion stem cell self-renewal animal cell aging cell culture DNA damage genetics hematopoietic stem cell metabolism physiology telomere Animals Cells, Cultured Cellular Senescence DNA Damage DNA-Binding Proteins Hematopoietic Stem Cells Humans Mice Reactive Oxygen Species Telomere |
| spellingShingle |
Pot1 protein reactive oxygen metabolite telomere binding protein unclassified drug DNA binding protein POT1 protein, mouse reactive oxygen metabolite age cells and cell components chromosome DNA gene expression protein reactive oxygen species animal cell apoptosis Article cell activity cell aging cell differentiation cell function cell protection cell survival controlled study DNA damage response down regulation ex vivo study gene expression hematopoietic stem cell human human cell microarray analysis mouse nonhuman oxidative phosphorylation protein expression protein function rejuvenation senescence stem cell culture stem cell expansion stem cell self-renewal animal cell aging cell culture DNA damage genetics hematopoietic stem cell metabolism physiology telomere Animals Cells, Cultured Cellular Senescence DNA Damage DNA-Binding Proteins Hematopoietic Stem Cells Humans Mice Reactive Oxygen Species Telomere Hosokawa, K MacArthur, B.D Ikushima, Y.M Toyama, H Masuhiro, Y Hanazawa, S Suda, T Arai, F The telomere binding protein Pot1 maintains haematopoietic stem cell activity with age |
| description |
10.1038/s41467-017-00935-4 |
| author2 |
MEDICINE |
| author_facet |
MEDICINE Hosokawa, K MacArthur, B.D Ikushima, Y.M Toyama, H Masuhiro, Y Hanazawa, S Suda, T Arai, F |
| format |
Article |
| author |
Hosokawa, K MacArthur, B.D Ikushima, Y.M Toyama, H Masuhiro, Y Hanazawa, S Suda, T Arai, F |
| author_sort |
Hosokawa, K |
| title |
The telomere binding protein Pot1 maintains haematopoietic stem cell activity with age |
| title_short |
The telomere binding protein Pot1 maintains haematopoietic stem cell activity with age |
| title_full |
The telomere binding protein Pot1 maintains haematopoietic stem cell activity with age |
| title_fullStr |
The telomere binding protein Pot1 maintains haematopoietic stem cell activity with age |
| title_full_unstemmed |
The telomere binding protein Pot1 maintains haematopoietic stem cell activity with age |
| title_sort |
telomere binding protein pot1 maintains haematopoietic stem cell activity with age |
| publisher |
Nature Publishing Group |
| publishDate |
2020 |
| url |
https://scholarbank.nus.edu.sg/handle/10635/178570 |
| _version_ |
1821193373371858944 |