Priming of lineage-specifying genes by Bcl11b is required for lineage choice in post-selection thymocytes

• Main Authors: Kojo, S, Tanaka, H, Endo, T.A, Muroi, S, Liu, Y, Seo, W, Tenno, M, Kakugawa, K, Naoe, Y, Nair, K, Moro, K, Katsuragi, Y, Kanai, A, Inaba, T, Egawa, T, Venkatesh, B, Minoda, A, Kominami, R, Taniuchi, I
• Other Authors: PAEDIATRICS
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: bcl11b protein; CD4 antigen; CD8 antigen; t helper inducing poz krueppel like factor; T lymphocyte receptor; transcription factor; transcription factor RUNX3; unclassified drug; zinc finger protein; Bcl11b protein, mouse; lymphocyte antigen receptor; repressor protein; Runx3 protein, mouse; Th-POK protein, mouse; tumor suppressor protein; cells and cell components; differentiation; gene expression; light intensity; protein; Article; cell lineage; cell selection; controlled study; enhancer region; gene repression; gene silencing; major histocompatibility complex; mouse; newborn; nonhuman; nucleotide sequence; protein expression; protein function; thymocyte; transcription regulation; zinc finger motif; animal; cell differentiation; cytology; cytotoxic T lymphocyte; gene expression regulation; genetics; helper cell; Animals; Cell Differentiation; Cell Lineage; Core Binding Factor Alpha 3 Subunit; Gene Expression Regulation; Mice; Receptors, Antigen, T-Cell; Repressor Proteins; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Helper-Inducer; Thymocytes; Transcription Factors; Tumor Suppressor Proteins
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/178573
• Institution: National University of Singapore

10.1038/s41467-017-00768-1