Suppression of TAK1 pathway by shear stress counteracts the inflammatory endothelial cell phenotype induced by oxidative stress and TGF-?1

Suppression of TAK1 pathway by shear stress counteracts the inflammatory endothelial cell phenotype induced by oxidative stress and TGF-?1

10.1038/srep42487

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Bibliographic Details
Main Authors:	Lee, E.S, Boldo, L.S, Fernandez, B.O, Feelisch, M, Harmsen, M.C
Other Authors:	PHYSIOLOGY
Format:	Article
Published:	2020
Subjects:	autacoid biological marker immunoglobulin enhancer binding protein MAP kinase kinase kinase 7 mitogen activated protein kinase 7 mitogen activated protein kinase kinase kinase reactive oxygen metabolite transforming growth factor beta1 animal biological model drug effect endothelium cell genetics human metabolism mitochondrion oxidative stress phenotype rat shear strength signal transduction umbilical vein endothelial cell Animals Biomarkers Endothelial Cells Human Umbilical Vein Endothelial Cells Humans Inflammation Mediators MAP Kinase Kinase Kinases Mitochondria Mitogen-Activated Protein Kinase 7 Models, Biological NF-kappa B Oxidative Stress Phenotype Rats Reactive Oxygen Species Shear Strength Signal Transduction Transforming Growth Factor beta1
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/178699
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Institution:	National University of Singapore

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Summary:	10.1038/srep42487