Downregulation of oncogenic RAS and c-Myc expression in MOLT-4 leukaemia cells by a salicylaldehyde semicarbazone copper(II) complex

Downregulation of oncogenic RAS and c-Myc expression in MOLT-4 leukaemia cells by a salicylaldehyde semicarbazone copper(II) complex

10.1038/srep36868

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Bibliographic Details
Main Authors: Goh, Y.-Y, Yan, Y.-K, Tan, N.S, Goh, S.-A, Li, S, Teoh, Y.-C, Lee, P.P.F
Other Authors: DEAN'S OFFICE (SSH SCH OF PUBLIC HEALTH)
Format: Article
Published: 2020
Subjects:
cisplatin
KRAS protein, human
Myc protein
MYC protein, human
organometallic compound
protein p21
semicarbazone derivative
apoptosis
down regulation
drug effect
drug potentiation
gene expression regulation
genetics
human
leukemia
MAPK signaling
metabolism
tumor cell line
Apoptosis
Cell Line, Tumor
Cisplatin
Down-Regulation
Drug Synergism
Gene Expression Regulation, Neoplastic
Humans
Leukemia
MAP Kinase Signaling System
Organometallic Compounds
Proto-Oncogene Proteins c-myc
Proto-Oncogene Proteins p21(ras)
Semicarbazones
Online Access:https://scholarbank.nus.edu.sg/handle/10635/178760
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Institution: National University of Singapore

Internet

https://scholarbank.nus.edu.sg/handle/10635/178760

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