Downregulation of oncogenic RAS and c-Myc expression in MOLT-4 leukaemia cells by a salicylaldehyde semicarbazone copper(II) complex

• Main Authors: Goh, Y.-Y, Yan, Y.-K, Tan, N.S, Goh, S.-A, Li, S, Teoh, Y.-C, Lee, P.P.F
• Other Authors: DEAN'S OFFICE (SSH SCH OF PUBLIC HEALTH)
• Format: Article
• Published: 2020
• Subjects: cisplatin; KRAS protein, human; Myc protein; MYC protein, human; organometallic compound; protein p21; semicarbazone derivative; apoptosis; down regulation; drug effect; drug potentiation; gene expression regulation; genetics; human; leukemia; MAPK signaling; metabolism; tumor cell line; Apoptosis; Cell Line, Tumor; Cisplatin; Down-Regulation; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Leukemia; MAP Kinase Signaling System; Organometallic Compounds; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins p21(ras); Semicarbazones
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/178760
• Institution: National University of Singapore

10.1038/srep36868