Time-resolved multimodal analysis of src homology 2 (SH2) domain binding in signaling by receptor tyrosine kinases

• Main Authors: Jadwin, J.A, Oh, D, Curran, T.G, Ogiue-Ikeda, M, Jia, L, White, F.M, Machida, K, Yu, J, Mayer, B.J
• Other Authors: MECHANOBIOLOGY INSTITUTE
• Format: Article
• Published: 2020
• Subjects: Crk like protein; epidermal growth factor; epidermal growth factor receptor; phospholipase C gamma1; protein SH2; protein tyrosine kinase; protein tyrosine phosphatase SHP 2; protein binding; Article; binding site; cell proliferation assay; controlled study; Far Western blotting; fluorescence microscopy; gene ontology; human; human cell; immobilized metal affinity chromatography; immunoprecipitation; liquid chromatography; mass spectrometry; protein expression; protein phosphorylation; protein purification; Western blotting; cell membrane; drug effects; epithelium cell; fluorescence imaging; metabolism; physiology; signal transduction; Src homology domain; tumor cell line; Blotting, Far-Western; Cell Line, Tumor; Cell Membrane; Epidermal Growth Factor; Epithelial Cells; Humans; Mass Spectrometry; Optical Imaging; Protein Binding; Receptor Protein-Tyrosine Kinases; Signal Transduction; src Homology Domains
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/178925
• Institution: National University of Singapore

10.7554/eLife.11835