Curcumin exerts a protective effect against premature ovarian failure in mice

• Main Authors: Yan, Z, Dai, Y, Fu, H, Zheng, Y, Bao, D, Yin, Y, Chen, Q, Nie, X, Hao, Q, Hou, D, Cui, Y
• Other Authors: DEPT OF PHARMACOLOGY
• Format: Article
• Published: BioScientifica Ltd. 2020
• Subjects: caspase 3; caspase 9; curcumin; galactose; malonaldehyde; messenger RNA; protein kinase B; protein p16; superoxide dismutase; 3-nitrotyrosine; 4-hydroxy-2-nonenal; 8-oxo-7-hydrodeoxyguanosine; aldehyde; cyclin dependent kinase inhibitor 2A; deoxyguanosine; Muellerian inhibiting factor; protective agent; tyrosine; animal cell; animal experiment; animal model; animal tissue; antral follicle; apoptosis; Article; controlled study; developmental stage; enzyme immunoassay; female; granulosa cell; immunohistochemistry; mouse; mRNA expression level; nonhuman; ovary function; ovary tissue; oxidative stress; premature ovarian failure; primordial follicle; priority journal; protein expression level; TUNEL assay; Western blotting; animal; C57BL mouse; disease model; drug effect; genetics; gonad; hypothalamus hypophysis system; metabolism; ovary; pathology; Aldehydes; Animals; Anti-Mullerian Hormone; Apoptosis; Curcumin; Cyclin-Dependent Kinase Inhibitor p16; Deoxyguanosine; Disease Models, Animal; Female; Galactose; Gonads; Hypothalamo-Hypophyseal System; Mice, Inbred C57BL; Ovary; Oxidative Stress; Primary Ovarian Insufficiency; Protective Agents; RNA, Messenger; Tyrosine
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/179044
• Institution: National University of Singapore

10.1530/JME-17-0214