Naltrexone ameliorates functional network abnormalities in alcohol-dependent individuals

• Main Authors: Morris, L.S, Baek, K, Tait, R, Elliott, R, Ersche, K.D, Flechais, R, McGonigle, J, Murphy, A, Nestor, L.J, Orban, C, Passetti, F, Paterson, L.M, Rabiner, I, Reed, L, Smith, D, Suckling, J, Taylor, E.M, Bullmore, E.T, Lingford-Hughes, A.R, Deakin, B, Nutt, D.J, Sahakian, B.J, Robbins, T.W, Voon, V, ICCAM Consorti
• Other Authors: ELECTRICAL AND COMPUTER ENGINEERING
• Format: Article
• Published: Blackwell Publishing Ltd 2020
• Subjects: naltrexone; placebo; drugs used in the treatment of addiction; adult; alcoholism; Article; cingulate gyrus; controlled study; drug effect; drug mechanism; exploratory research; female; functional connectivity; functional magnetic resonance imaging; human; left hemisphere; major clinical study; male; medial orbitofrontal cortex; middle frontal gyrus; middle occipital gyrus; multiple drug abuse; olfactory bulb; onset age; parahippocampal gyrus; priority journal; right hemisphere; single drug dose; supplementary motor area; brain; diagnostic imaging; drug dependence; functional neuroimaging; middle aged; nerve tract; normal human; nuclear magnetic resonance imaging; pathophysiology; young adult; Adult; Alcohol Deterrents; Alcoholism; Brain; Female; Functional Neuroimaging; Healthy Volunteers; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Naltrexone; Neural Pathways; Substance-Related Disorders; Young Adult
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/179068
• Institution: National University of Singapore

10.1111/adb.12503