NBEAL2 is required for neutrophil and NK cell function and pathogen defense

10.1172/JCI91684

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Main Authors:	Sowerby, J.M, Thomas, D.C, Clare, S, Espéli, M, Guerrero, J.A, Hoenderdos, K, Harcourt, K, Marsden, M, Abdul-Karim, J, Clement, M, Antrobus, R, Umrania, Y, Barton, P.R, Flint, S.M, Juss, J.K, Condliffe, A.M, Lyons, P.A, Humphreys, I.R, Chilvers, E.R, Ouwehand, W.H, Dougan, G, Smith, K.G.C
Other Authors:	MEDICINE
Format:	Article
Published:	American Society for Clinical Investigation 2020
Subjects:	reduced nicotinamide adenine dinucleotide phosphate oxidase superoxide NBEAL2 protein, human plasma protein animal cell animal experiment animal model Article cell function Cytomegalovirus cytomegalovirus infection degranulation gene immune system immunity mouse natural killer cell nbeal2 gene neutrophil nonhuman phagocyte phenotype priority journal respiratory burst Staphylococcus aureus animal cytosol genetics gray platelet syndrome human immunophenotyping knockout mouse metabolism mutation Staphylococcus infection thrombocyte Animals Blood Platelets Blood Proteins Cytosol Gray Platelet Syndrome Humans Immune System Immunophenotyping Killer Cells, Natural Mice Mice, Knockout Mutation NADPH Oxidase Neutrophils Phenotype Staphylococcal Infections
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/179095
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1790952024-04-24T05:48:25Z NBEAL2 is required for neutrophil and NK cell function and pathogen defense Sowerby, J.M Thomas, D.C Clare, S Espéli, M Guerrero, J.A Hoenderdos, K Harcourt, K Marsden, M Abdul-Karim, J Clement, M Antrobus, R Umrania, Y Barton, P.R Flint, S.M Juss, J.K Condliffe, A.M Lyons, P.A Humphreys, I.R Chilvers, E.R Ouwehand, W.H Dougan, G Smith, K.G.C MEDICINE reduced nicotinamide adenine dinucleotide phosphate oxidase superoxide NBEAL2 protein, human plasma protein reduced nicotinamide adenine dinucleotide phosphate oxidase animal cell animal experiment animal model Article cell function Cytomegalovirus cytomegalovirus infection degranulation gene immune system immunity mouse natural killer cell nbeal2 gene neutrophil nonhuman phagocyte phenotype priority journal respiratory burst Staphylococcus aureus animal cytosol genetics gray platelet syndrome human immunophenotyping knockout mouse metabolism mutation natural killer cell neutrophil Staphylococcus infection thrombocyte Animals Blood Platelets Blood Proteins Cytosol Gray Platelet Syndrome Humans Immune System Immunophenotyping Killer Cells, Natural Mice Mice, Knockout Mutation NADPH Oxidase Neutrophils Phenotype Staphylococcal Infections Staphylococcus aureus 10.1172/JCI91684 Journal of Clinical Investigation 127 9 3521-3526 2020-10-22T07:38:00Z 2020-10-22T07:38:00Z 2017 Article Sowerby, J.M, Thomas, D.C, Clare, S, Espéli, M, Guerrero, J.A, Hoenderdos, K, Harcourt, K, Marsden, M, Abdul-Karim, J, Clement, M, Antrobus, R, Umrania, Y, Barton, P.R, Flint, S.M, Juss, J.K, Condliffe, A.M, Lyons, P.A, Humphreys, I.R, Chilvers, E.R, Ouwehand, W.H, Dougan, G, Smith, K.G.C (2017). NBEAL2 is required for neutrophil and NK cell function and pathogen defense. Journal of Clinical Investigation 127 (9) : 3521-3526. ScholarBank@NUS Repository. https://doi.org/10.1172/JCI91684 00219738 https://scholarbank.nus.edu.sg/handle/10635/179095 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ American Society for Clinical Investigation Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	reduced nicotinamide adenine dinucleotide phosphate oxidase superoxide NBEAL2 protein, human plasma protein reduced nicotinamide adenine dinucleotide phosphate oxidase animal cell animal experiment animal model Article cell function Cytomegalovirus cytomegalovirus infection degranulation gene immune system immunity mouse natural killer cell nbeal2 gene neutrophil nonhuman phagocyte phenotype priority journal respiratory burst Staphylococcus aureus animal cytosol genetics gray platelet syndrome human immunophenotyping knockout mouse metabolism mutation natural killer cell neutrophil Staphylococcus infection thrombocyte Animals Blood Platelets Blood Proteins Cytosol Gray Platelet Syndrome Humans Immune System Immunophenotyping Killer Cells, Natural Mice Mice, Knockout Mutation NADPH Oxidase Neutrophils Phenotype Staphylococcal Infections Staphylococcus aureus
spellingShingle	reduced nicotinamide adenine dinucleotide phosphate oxidase superoxide NBEAL2 protein, human plasma protein reduced nicotinamide adenine dinucleotide phosphate oxidase animal cell animal experiment animal model Article cell function Cytomegalovirus cytomegalovirus infection degranulation gene immune system immunity mouse natural killer cell nbeal2 gene neutrophil nonhuman phagocyte phenotype priority journal respiratory burst Staphylococcus aureus animal cytosol genetics gray platelet syndrome human immunophenotyping knockout mouse metabolism mutation natural killer cell neutrophil Staphylococcus infection thrombocyte Animals Blood Platelets Blood Proteins Cytosol Gray Platelet Syndrome Humans Immune System Immunophenotyping Killer Cells, Natural Mice Mice, Knockout Mutation NADPH Oxidase Neutrophils Phenotype Staphylococcal Infections Staphylococcus aureus Sowerby, J.M Thomas, D.C Clare, S Espéli, M Guerrero, J.A Hoenderdos, K Harcourt, K Marsden, M Abdul-Karim, J Clement, M Antrobus, R Umrania, Y Barton, P.R Flint, S.M Juss, J.K Condliffe, A.M Lyons, P.A Humphreys, I.R Chilvers, E.R Ouwehand, W.H Dougan, G Smith, K.G.C NBEAL2 is required for neutrophil and NK cell function and pathogen defense
description	10.1172/JCI91684
author2	MEDICINE
author_facet	MEDICINE Sowerby, J.M Thomas, D.C Clare, S Espéli, M Guerrero, J.A Hoenderdos, K Harcourt, K Marsden, M Abdul-Karim, J Clement, M Antrobus, R Umrania, Y Barton, P.R Flint, S.M Juss, J.K Condliffe, A.M Lyons, P.A Humphreys, I.R Chilvers, E.R Ouwehand, W.H Dougan, G Smith, K.G.C
format	Article
author	Sowerby, J.M Thomas, D.C Clare, S Espéli, M Guerrero, J.A Hoenderdos, K Harcourt, K Marsden, M Abdul-Karim, J Clement, M Antrobus, R Umrania, Y Barton, P.R Flint, S.M Juss, J.K Condliffe, A.M Lyons, P.A Humphreys, I.R Chilvers, E.R Ouwehand, W.H Dougan, G Smith, K.G.C
author_sort	Sowerby, J.M
title	NBEAL2 is required for neutrophil and NK cell function and pathogen defense
title_short	NBEAL2 is required for neutrophil and NK cell function and pathogen defense
title_full	NBEAL2 is required for neutrophil and NK cell function and pathogen defense
title_fullStr	NBEAL2 is required for neutrophil and NK cell function and pathogen defense
title_full_unstemmed	NBEAL2 is required for neutrophil and NK cell function and pathogen defense
title_sort	nbeal2 is required for neutrophil and nk cell function and pathogen defense
publisher	American Society for Clinical Investigation
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/179095
_version_	1800914537991372800

NBEAL2 is required for neutrophil and NK cell function and pathogen defense

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