Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation

10.1084/jem.20161418

Saved in:
Bibliographic Details
Main Authors: Mead, A.J, Neo, W.H, Barkas, N, Matsuoka, S, Giustacchini, A, Facchini, R, Thongjuea, S, Jamieson, L, Booth, C.A.G, Fordham, N, Di Genua, C, Atkinson, D, Chowdhury, O, Repapi, E, Gray, N, Kharazi, S, Clark, S.-A, Bouriez, T, Woll, P, Suda, T, Nerlov, C, Jacobsen, S.E.W
Other Authors: MEDICINE
Format: Article
Published: Rockefeller University Press 2020
Subjects:
Online Access:https://scholarbank.nus.edu.sg/handle/10635/179194
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: National University of Singapore
id sg-nus-scholar.10635-179194
record_format dspace
spelling sg-nus-scholar.10635-1791942024-11-13T19:59:20Z Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation Mead, A.J Neo, W.H Barkas, N Matsuoka, S Giustacchini, A Facchini, R Thongjuea, S Jamieson, L Booth, C.A.G Fordham, N Di Genua, C Atkinson, D Chowdhury, O Repapi, E Gray, N Kharazi, S Clark, S.-A Bouriez, T Woll, P Suda, T Nerlov, C Jacobsen, S.E.W MEDICINE CD135 antigen messenger RNA tumor necrosis factor CD135 antigen etanercept FLT3 protein, human nonsteroid antiinflammatory agent tumor necrosis factor animal cell Article bone marrow stroma cell endothelium cell gene expression hematopoietic stem cell internal tandem duplication mesenchymal stroma cell mouse myeloproliferative disorder nonhuman phenotype priority journal protein expression single cell analysis stem cell niche tandem repeat animal antagonists and inhibitors bone marrow cell bone marrow transplantation C57BL mouse cell culture cell proliferation drug effects gene expression profiling genetics hematopoietic stem cell metabolism mutation procedures reverse transcription polymerase chain reaction stem cell niche tandem repeat transgenic mouse Animals Anti-Inflammatory Agents, Non-Steroidal Bone Marrow Cells Bone Marrow Transplantation Cell Proliferation Cells, Cultured Etanercept fms-Like Tyrosine Kinase 3 Gene Expression Profiling Hematopoietic Stem Cells Mesenchymal Stromal Cells Mice, Inbred C57BL Mice, Transgenic Mutation Reverse Transcriptase Polymerase Chain Reaction Single-Cell Analysis Stem Cell Niche Tandem Repeat Sequences Tumor Necrosis Factor-alpha 10.1084/jem.20161418 Journal of Experimental Medicine 214 7 2005-2021 2020-10-23T02:27:28Z 2020-10-23T02:27:28Z 2017 Article Mead, A.J, Neo, W.H, Barkas, N, Matsuoka, S, Giustacchini, A, Facchini, R, Thongjuea, S, Jamieson, L, Booth, C.A.G, Fordham, N, Di Genua, C, Atkinson, D, Chowdhury, O, Repapi, E, Gray, N, Kharazi, S, Clark, S.-A, Bouriez, T, Woll, P, Suda, T, Nerlov, C, Jacobsen, S.E.W (2017). Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation. Journal of Experimental Medicine 214 (7) : 2005-2021. ScholarBank@NUS Repository. https://doi.org/10.1084/jem.20161418 00221007 https://scholarbank.nus.edu.sg/handle/10635/179194 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Rockefeller University Press Unpaywall 20201031
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic CD135 antigen
messenger RNA
tumor necrosis factor
CD135 antigen
etanercept
FLT3 protein, human
nonsteroid antiinflammatory agent
tumor necrosis factor
animal cell
Article
bone marrow stroma cell
endothelium cell
gene expression
hematopoietic stem cell
internal tandem duplication
mesenchymal stroma cell
mouse
myeloproliferative disorder
nonhuman
phenotype
priority journal
protein expression
single cell analysis
stem cell niche
tandem repeat
animal
antagonists and inhibitors
bone marrow cell
bone marrow transplantation
C57BL mouse
cell culture
cell proliferation
drug effects
gene expression profiling
genetics
hematopoietic stem cell
metabolism
mutation
procedures
reverse transcription polymerase chain reaction
stem cell niche
tandem repeat
transgenic mouse
Animals
Anti-Inflammatory Agents, Non-Steroidal
Bone Marrow Cells
Bone Marrow Transplantation
Cell Proliferation
Cells, Cultured
Etanercept
fms-Like Tyrosine Kinase 3
Gene Expression Profiling
Hematopoietic Stem Cells
Mesenchymal Stromal Cells
Mice, Inbred C57BL
Mice, Transgenic
Mutation
Reverse Transcriptase Polymerase Chain Reaction
Single-Cell Analysis
Stem Cell Niche
Tandem Repeat Sequences
Tumor Necrosis Factor-alpha
spellingShingle CD135 antigen
messenger RNA
tumor necrosis factor
CD135 antigen
etanercept
FLT3 protein, human
nonsteroid antiinflammatory agent
tumor necrosis factor
animal cell
Article
bone marrow stroma cell
endothelium cell
gene expression
hematopoietic stem cell
internal tandem duplication
mesenchymal stroma cell
mouse
myeloproliferative disorder
nonhuman
phenotype
priority journal
protein expression
single cell analysis
stem cell niche
tandem repeat
animal
antagonists and inhibitors
bone marrow cell
bone marrow transplantation
C57BL mouse
cell culture
cell proliferation
drug effects
gene expression profiling
genetics
hematopoietic stem cell
metabolism
mutation
procedures
reverse transcription polymerase chain reaction
stem cell niche
tandem repeat
transgenic mouse
Animals
Anti-Inflammatory Agents, Non-Steroidal
Bone Marrow Cells
Bone Marrow Transplantation
Cell Proliferation
Cells, Cultured
Etanercept
fms-Like Tyrosine Kinase 3
Gene Expression Profiling
Hematopoietic Stem Cells
Mesenchymal Stromal Cells
Mice, Inbred C57BL
Mice, Transgenic
Mutation
Reverse Transcriptase Polymerase Chain Reaction
Single-Cell Analysis
Stem Cell Niche
Tandem Repeat Sequences
Tumor Necrosis Factor-alpha
Mead, A.J
Neo, W.H
Barkas, N
Matsuoka, S
Giustacchini, A
Facchini, R
Thongjuea, S
Jamieson, L
Booth, C.A.G
Fordham, N
Di Genua, C
Atkinson, D
Chowdhury, O
Repapi, E
Gray, N
Kharazi, S
Clark, S.-A
Bouriez, T
Woll, P
Suda, T
Nerlov, C
Jacobsen, S.E.W
Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation
description 10.1084/jem.20161418
author2 MEDICINE
author_facet MEDICINE
Mead, A.J
Neo, W.H
Barkas, N
Matsuoka, S
Giustacchini, A
Facchini, R
Thongjuea, S
Jamieson, L
Booth, C.A.G
Fordham, N
Di Genua, C
Atkinson, D
Chowdhury, O
Repapi, E
Gray, N
Kharazi, S
Clark, S.-A
Bouriez, T
Woll, P
Suda, T
Nerlov, C
Jacobsen, S.E.W
format Article
author Mead, A.J
Neo, W.H
Barkas, N
Matsuoka, S
Giustacchini, A
Facchini, R
Thongjuea, S
Jamieson, L
Booth, C.A.G
Fordham, N
Di Genua, C
Atkinson, D
Chowdhury, O
Repapi, E
Gray, N
Kharazi, S
Clark, S.-A
Bouriez, T
Woll, P
Suda, T
Nerlov, C
Jacobsen, S.E.W
author_sort Mead, A.J
title Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation
title_short Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation
title_full Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation
title_fullStr Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation
title_full_unstemmed Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation
title_sort niche-mediated depletion of the normal hematopoietic stem cell reservoir by flt3-itd-induced myeloproliferation
publisher Rockefeller University Press
publishDate 2020
url https://scholarbank.nus.edu.sg/handle/10635/179194
_version_ 1821212558493745152