Ginkgolic acid C 17:1, derived from Ginkgo biloba leaves, suppresses constitutive and inducible STAT3 activation through induction of PTEN and SHP-1 tyrosine phosphatase

10.3390/molecules22020276

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Main Authors:	Baek, S.H, Lee, J.H, Kim, C, Ko, J.-H, Ryu, S.-H, Lee, S.-G, Yang, W.M, Um, J.-Y, Chinnathambi, A, Alharbi, S.A, Sethi, G, Ahn, K.S, Choi, D.-K., Ganesan, P.
Other Authors:	DEPT OF PHARMACOLOGY
Format:	Article
Published:	MDPI AG 2020
Subjects:	ginkgolic acid interleukin 6 phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase plant extract protein binding protein tyrosine phosphatase SHP 1 salicylic acid derivative STAT3 protein agonists apoptosis cell cycle cell proliferation chemistry drug effects gene expression regulation genetics Ginkgo biloba human metabolism mitochondrial membrane potential multiple myeloma phosphorylation plant leaf tumor cell line Apoptosis Cell Cycle Cell Line, Tumor Cell Proliferation Gene Expression Regulation, Neoplastic Humans Interleukin-6 Membrane Potential, Mitochondrial Multiple Myeloma Phosphorylation Plant Extracts Plant Leaves Protein Binding Protein Tyrosine Phosphatase, Non-Receptor Type 6 PTEN Phosphohydrolase Salicylates STAT3 Transcription Factor
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/179240
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1792402023-11-01T08:09:27Z Ginkgolic acid C 17:1, derived from Ginkgo biloba leaves, suppresses constitutive and inducible STAT3 activation through induction of PTEN and SHP-1 tyrosine phosphatase Baek, S.H Lee, J.H Kim, C Ko, J.-H Ryu, S.-H Lee, S.-G Yang, W.M Um, J.-Y Chinnathambi, A Alharbi, S.A Sethi, G Ahn, K.S Choi, D.-K. Ganesan, P. DEPT OF PHARMACOLOGY ginkgolic acid interleukin 6 phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase plant extract protein binding protein tyrosine phosphatase SHP 1 salicylic acid derivative STAT3 protein agonists apoptosis cell cycle cell proliferation chemistry drug effects gene expression regulation genetics Ginkgo biloba human metabolism mitochondrial membrane potential multiple myeloma phosphorylation plant leaf tumor cell line Apoptosis Cell Cycle Cell Line, Tumor Cell Proliferation Gene Expression Regulation, Neoplastic Ginkgo biloba Humans Interleukin-6 Membrane Potential, Mitochondrial Multiple Myeloma Phosphorylation Plant Extracts Plant Leaves Protein Binding Protein Tyrosine Phosphatase, Non-Receptor Type 6 PTEN Phosphohydrolase Salicylates STAT3 Transcription Factor 10.3390/molecules22020276 Molecules 22 2 276 2020-10-23T02:34:52Z 2020-10-23T02:34:52Z 2017 Article Baek, S.H, Lee, J.H, Kim, C, Ko, J.-H, Ryu, S.-H, Lee, S.-G, Yang, W.M, Um, J.-Y, Chinnathambi, A, Alharbi, S.A, Sethi, G, Ahn, K.S, Choi, D.-K., Ganesan, P. (2017). Ginkgolic acid C 17:1, derived from Ginkgo biloba leaves, suppresses constitutive and inducible STAT3 activation through induction of PTEN and SHP-1 tyrosine phosphatase. Molecules 22 (2) : 276. ScholarBank@NUS Repository. https://doi.org/10.3390/molecules22020276 14203049 https://scholarbank.nus.edu.sg/handle/10635/179240 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ MDPI AG Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	ginkgolic acid interleukin 6 phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase plant extract protein binding protein tyrosine phosphatase SHP 1 salicylic acid derivative STAT3 protein agonists apoptosis cell cycle cell proliferation chemistry drug effects gene expression regulation genetics Ginkgo biloba human metabolism mitochondrial membrane potential multiple myeloma phosphorylation plant leaf tumor cell line Apoptosis Cell Cycle Cell Line, Tumor Cell Proliferation Gene Expression Regulation, Neoplastic Ginkgo biloba Humans Interleukin-6 Membrane Potential, Mitochondrial Multiple Myeloma Phosphorylation Plant Extracts Plant Leaves Protein Binding Protein Tyrosine Phosphatase, Non-Receptor Type 6 PTEN Phosphohydrolase Salicylates STAT3 Transcription Factor
spellingShingle	ginkgolic acid interleukin 6 phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase plant extract protein binding protein tyrosine phosphatase SHP 1 salicylic acid derivative STAT3 protein agonists apoptosis cell cycle cell proliferation chemistry drug effects gene expression regulation genetics Ginkgo biloba human metabolism mitochondrial membrane potential multiple myeloma phosphorylation plant leaf tumor cell line Apoptosis Cell Cycle Cell Line, Tumor Cell Proliferation Gene Expression Regulation, Neoplastic Ginkgo biloba Humans Interleukin-6 Membrane Potential, Mitochondrial Multiple Myeloma Phosphorylation Plant Extracts Plant Leaves Protein Binding Protein Tyrosine Phosphatase, Non-Receptor Type 6 PTEN Phosphohydrolase Salicylates STAT3 Transcription Factor Baek, S.H Lee, J.H Kim, C Ko, J.-H Ryu, S.-H Lee, S.-G Yang, W.M Um, J.-Y Chinnathambi, A Alharbi, S.A Sethi, G Ahn, K.S Choi, D.-K. Ganesan, P. Ginkgolic acid C 17:1, derived from Ginkgo biloba leaves, suppresses constitutive and inducible STAT3 activation through induction of PTEN and SHP-1 tyrosine phosphatase
description	10.3390/molecules22020276
author2	DEPT OF PHARMACOLOGY
author_facet	DEPT OF PHARMACOLOGY Baek, S.H Lee, J.H Kim, C Ko, J.-H Ryu, S.-H Lee, S.-G Yang, W.M Um, J.-Y Chinnathambi, A Alharbi, S.A Sethi, G Ahn, K.S Choi, D.-K. Ganesan, P.
format	Article
author	Baek, S.H Lee, J.H Kim, C Ko, J.-H Ryu, S.-H Lee, S.-G Yang, W.M Um, J.-Y Chinnathambi, A Alharbi, S.A Sethi, G Ahn, K.S Choi, D.-K. Ganesan, P.
author_sort	Baek, S.H
title	Ginkgolic acid C 17:1, derived from Ginkgo biloba leaves, suppresses constitutive and inducible STAT3 activation through induction of PTEN and SHP-1 tyrosine phosphatase
title_short	Ginkgolic acid C 17:1, derived from Ginkgo biloba leaves, suppresses constitutive and inducible STAT3 activation through induction of PTEN and SHP-1 tyrosine phosphatase
title_full	Ginkgolic acid C 17:1, derived from Ginkgo biloba leaves, suppresses constitutive and inducible STAT3 activation through induction of PTEN and SHP-1 tyrosine phosphatase
title_fullStr	Ginkgolic acid C 17:1, derived from Ginkgo biloba leaves, suppresses constitutive and inducible STAT3 activation through induction of PTEN and SHP-1 tyrosine phosphatase
title_full_unstemmed	Ginkgolic acid C 17:1, derived from Ginkgo biloba leaves, suppresses constitutive and inducible STAT3 activation through induction of PTEN and SHP-1 tyrosine phosphatase
title_sort	ginkgolic acid c 17:1, derived from ginkgo biloba leaves, suppresses constitutive and inducible stat3 activation through induction of pten and shp-1 tyrosine phosphatase
publisher	MDPI AG
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/179240
_version_	1781792325848006656

Ginkgolic acid C 17:1, derived from Ginkgo biloba leaves, suppresses constitutive and inducible STAT3 activation through induction of PTEN and SHP-1 tyrosine phosphatase

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