Complement evasion mediated by enhancement of captured factor H: Implications for protection of self-surfaces from complement

• Main Authors: Herbert, A.P, Makou, E, Chen, Z.A, Kerr, H, Richards, A, Rappsilber, J, Barlow, P.N
• Other Authors: MEDICINE
• Format: Article
• Published: American Association of Immunologists 2020
• Subjects: bacterial protein; CD59 antigen; classical complement pathway C3 C5 convertase; complement component C3b; complement component C3d; complement factor H; decay accelerating factor; OspC protein; SUMO protein; unclassified drug; SpsA protein, Streptococcus pneumoniae; amino terminal sequence; animal cell; Article; bacterial strain; binding site; carboxy terminal sequence; complement alternative pathway; complement inhibition; complement system; conformational transition; controlled study; hemoglobinuria; hemolysis; hemolysis assay; immune evasion; mass spectrometry; nonhuman; nuclear magnetic resonance; nuclear magnetic resonance spectroscopy; polyacrylamide gel electrophoresis; priority journal; protein cleavage; protein degradation; protein domain; site directed mutagenesis; Streptococcus pneumoniae; surface plasmon resonance; chemistry; human; immunology; paroxysmal nocturnal hemoglobinuria; protein tertiary structure; Bacterial Proteins; Complement C3b; Complement Factor H; Hemoglobinuria, Paroxysmal; Humans; Protein Structure, Tertiary
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/179638
• Institution: National University of Singapore

10.4049/jimmunol.1501388