Pharmacological actions of nobiletin in the modulation of platelet function
10.1111/bph.13191
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2020
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sg-nus-scholar.10635-1796552024-11-08T22:48:53Z Pharmacological actions of nobiletin in the modulation of platelet function Vaiyapuri, S Roweth, H Ali, M.S Unsworth, A.J Stainer, A.R Flora, G.D Crescente, M Jones, C.I Moraes, L.A Gibbins, J.M PHYSIOLOGY calcium cyclic GMP cyclic nucleotide fibrinogen glycoprotein glycoprotein VI integrin integrin alpha2beta3 nobiletin phospholipase C gamma2 phosphoprotein protein kinase B unclassified drug calcium cyclic GMP fibrinogen fibrinogen receptor flavone derivative nobiletin protein kinase B aggregometry animal cell Article binding affinity binding site bleeding time blood clotting calcium mobilization controlled study drug effect drug mechanism drug potency enzyme inactivation enzyme phosphorylation homeostasis human human cell in vitro study in vivo study measurement molecular dynamics mouse nonhuman priority journal protein binding protein phosphorylation signal transduction thrombocyte aggregation thrombocyte function animal blood clotting test C57BL mouse cell culture chemically induced drug effects metabolism physiology thrombocyte thrombocyte activation thrombosis Animals Blood Coagulation Tests Blood Platelets Calcium Cells, Cultured Cyclic GMP Fibrinogen Flavones Humans Mice, Inbred C57BL Platelet Activation Platelet Aggregation Platelet Glycoprotein GPIIb-IIIa Complex Proto-Oncogene Proteins c-akt Thrombosis 10.1111/bph.13191 British Journal of Pharmacology 172 16 4133-4145 2020-10-23T08:12:13Z 2020-10-23T08:12:13Z 2015 Article Vaiyapuri, S, Roweth, H, Ali, M.S, Unsworth, A.J, Stainer, A.R, Flora, G.D, Crescente, M, Jones, C.I, Moraes, L.A, Gibbins, J.M (2015). Pharmacological actions of nobiletin in the modulation of platelet function. British Journal of Pharmacology 172 (16) : 4133-4145. ScholarBank@NUS Repository. https://doi.org/10.1111/bph.13191 0007-1188 https://scholarbank.nus.edu.sg/handle/10635/179655 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ John Wiley and Sons Inc. Unpaywall 20201031 |
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calcium cyclic GMP cyclic nucleotide fibrinogen glycoprotein glycoprotein VI integrin integrin alpha2beta3 nobiletin phospholipase C gamma2 phosphoprotein protein kinase B unclassified drug calcium cyclic GMP fibrinogen fibrinogen receptor flavone derivative nobiletin protein kinase B aggregometry animal cell Article binding affinity binding site bleeding time blood clotting calcium mobilization controlled study drug effect drug mechanism drug potency enzyme inactivation enzyme phosphorylation homeostasis human human cell in vitro study in vivo study measurement molecular dynamics mouse nonhuman priority journal protein binding protein phosphorylation signal transduction thrombocyte aggregation thrombocyte function animal blood clotting test C57BL mouse cell culture chemically induced drug effects metabolism physiology thrombocyte thrombocyte activation thrombosis Animals Blood Coagulation Tests Blood Platelets Calcium Cells, Cultured Cyclic GMP Fibrinogen Flavones Humans Mice, Inbred C57BL Platelet Activation Platelet Aggregation Platelet Glycoprotein GPIIb-IIIa Complex Proto-Oncogene Proteins c-akt Thrombosis |
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calcium cyclic GMP cyclic nucleotide fibrinogen glycoprotein glycoprotein VI integrin integrin alpha2beta3 nobiletin phospholipase C gamma2 phosphoprotein protein kinase B unclassified drug calcium cyclic GMP fibrinogen fibrinogen receptor flavone derivative nobiletin protein kinase B aggregometry animal cell Article binding affinity binding site bleeding time blood clotting calcium mobilization controlled study drug effect drug mechanism drug potency enzyme inactivation enzyme phosphorylation homeostasis human human cell in vitro study in vivo study measurement molecular dynamics mouse nonhuman priority journal protein binding protein phosphorylation signal transduction thrombocyte aggregation thrombocyte function animal blood clotting test C57BL mouse cell culture chemically induced drug effects metabolism physiology thrombocyte thrombocyte activation thrombosis Animals Blood Coagulation Tests Blood Platelets Calcium Cells, Cultured Cyclic GMP Fibrinogen Flavones Humans Mice, Inbred C57BL Platelet Activation Platelet Aggregation Platelet Glycoprotein GPIIb-IIIa Complex Proto-Oncogene Proteins c-akt Thrombosis Vaiyapuri, S Roweth, H Ali, M.S Unsworth, A.J Stainer, A.R Flora, G.D Crescente, M Jones, C.I Moraes, L.A Gibbins, J.M Pharmacological actions of nobiletin in the modulation of platelet function |
description |
10.1111/bph.13191 |
author2 |
PHYSIOLOGY |
author_facet |
PHYSIOLOGY Vaiyapuri, S Roweth, H Ali, M.S Unsworth, A.J Stainer, A.R Flora, G.D Crescente, M Jones, C.I Moraes, L.A Gibbins, J.M |
format |
Article |
author |
Vaiyapuri, S Roweth, H Ali, M.S Unsworth, A.J Stainer, A.R Flora, G.D Crescente, M Jones, C.I Moraes, L.A Gibbins, J.M |
author_sort |
Vaiyapuri, S |
title |
Pharmacological actions of nobiletin in the modulation of platelet function |
title_short |
Pharmacological actions of nobiletin in the modulation of platelet function |
title_full |
Pharmacological actions of nobiletin in the modulation of platelet function |
title_fullStr |
Pharmacological actions of nobiletin in the modulation of platelet function |
title_full_unstemmed |
Pharmacological actions of nobiletin in the modulation of platelet function |
title_sort |
pharmacological actions of nobiletin in the modulation of platelet function |
publisher |
John Wiley and Sons Inc. |
publishDate |
2020 |
url |
https://scholarbank.nus.edu.sg/handle/10635/179655 |
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1821214426166984704 |