Overexpression of SOX4 correlates with poor prognosis of acute myeloid leukemia and is leukemogenic in zebrafish

10.1038/bcj.2017.74

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Main Authors:	Lu, J.-W, Hsieh, M.-S, Hou, H.-A, Chen, C.-Y, Tien, H.-F, Lin, L.-I
Other Authors:	BIOLOGICAL SCIENCES
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	CD135 antigen messenger RNA nucleophosmin transcription factor Sox4 transcription factor Sox tumor protein zebrafish protein acute myeloid leukemia adult animal experiment animal model animal tissue Article bone marrow cell cancer patient cancer prognosis cell dedifferentiation cell infiltration controlled study de novo acute myeloid leukemia disease free survival embryo follow up human immunocytochemistry in situ hybridization induction chemotherapy karyotype karyotyping kidney structure leukemogenesis leukocyte count major clinical study microscopy myeloid progenitor cell myelopoiesis nonhuman overall survival patient polymerase chain reaction protein expression quantitative analysis remission reverse transcription polymerase chain reaction tissue section zebra fish animal biosynthesis gene expression regulation genetics metabolism pathology transgenic animal Animals Animals, Genetically Modified Gene Expression Regulation, Neoplastic Leukemia, Myeloid, Acute Myelopoiesis Neoplasm Proteins SOXC Transcription Factors Zebrafish Zebrafish Proteins
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/179702
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1797022024-04-03T10:12:08Z Overexpression of SOX4 correlates with poor prognosis of acute myeloid leukemia and is leukemogenic in zebrafish Lu, J.-W Hsieh, M.-S Hou, H.-A Chen, C.-Y Tien, H.-F Lin, L.-I BIOLOGICAL SCIENCES CD135 antigen messenger RNA nucleophosmin transcription factor Sox4 transcription factor Sox tumor protein zebrafish protein acute myeloid leukemia adult animal experiment animal model animal tissue Article bone marrow cell cancer patient cancer prognosis cell dedifferentiation cell infiltration controlled study de novo acute myeloid leukemia disease free survival embryo follow up human immunocytochemistry in situ hybridization induction chemotherapy karyotype karyotyping kidney structure leukemogenesis leukocyte count major clinical study microscopy myeloid progenitor cell myelopoiesis nonhuman overall survival patient polymerase chain reaction protein expression quantitative analysis remission reverse transcription polymerase chain reaction tissue section zebra fish acute myeloid leukemia animal biosynthesis gene expression regulation genetics metabolism myelopoiesis pathology transgenic animal Animals Animals, Genetically Modified Gene Expression Regulation, Neoplastic Leukemia, Myeloid, Acute Myelopoiesis Neoplasm Proteins SOXC Transcription Factors Zebrafish Zebrafish Proteins 10.1038/bcj.2017.74 Blood Cancer Journal 7 8 e593 2020-10-26T02:43:14Z 2020-10-26T02:43:14Z 2017 Article Lu, J.-W, Hsieh, M.-S, Hou, H.-A, Chen, C.-Y, Tien, H.-F, Lin, L.-I (2017). Overexpression of SOX4 correlates with poor prognosis of acute myeloid leukemia and is leukemogenic in zebrafish. Blood Cancer Journal 7 (8) : e593. ScholarBank@NUS Repository. https://doi.org/10.1038/bcj.2017.74 2044-5385 https://scholarbank.nus.edu.sg/handle/10635/179702 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Nature Publishing Group Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	CD135 antigen messenger RNA nucleophosmin transcription factor Sox4 transcription factor Sox tumor protein zebrafish protein acute myeloid leukemia adult animal experiment animal model animal tissue Article bone marrow cell cancer patient cancer prognosis cell dedifferentiation cell infiltration controlled study de novo acute myeloid leukemia disease free survival embryo follow up human immunocytochemistry in situ hybridization induction chemotherapy karyotype karyotyping kidney structure leukemogenesis leukocyte count major clinical study microscopy myeloid progenitor cell myelopoiesis nonhuman overall survival patient polymerase chain reaction protein expression quantitative analysis remission reverse transcription polymerase chain reaction tissue section zebra fish acute myeloid leukemia animal biosynthesis gene expression regulation genetics metabolism myelopoiesis pathology transgenic animal Animals Animals, Genetically Modified Gene Expression Regulation, Neoplastic Leukemia, Myeloid, Acute Myelopoiesis Neoplasm Proteins SOXC Transcription Factors Zebrafish Zebrafish Proteins
spellingShingle	CD135 antigen messenger RNA nucleophosmin transcription factor Sox4 transcription factor Sox tumor protein zebrafish protein acute myeloid leukemia adult animal experiment animal model animal tissue Article bone marrow cell cancer patient cancer prognosis cell dedifferentiation cell infiltration controlled study de novo acute myeloid leukemia disease free survival embryo follow up human immunocytochemistry in situ hybridization induction chemotherapy karyotype karyotyping kidney structure leukemogenesis leukocyte count major clinical study microscopy myeloid progenitor cell myelopoiesis nonhuman overall survival patient polymerase chain reaction protein expression quantitative analysis remission reverse transcription polymerase chain reaction tissue section zebra fish acute myeloid leukemia animal biosynthesis gene expression regulation genetics metabolism myelopoiesis pathology transgenic animal Animals Animals, Genetically Modified Gene Expression Regulation, Neoplastic Leukemia, Myeloid, Acute Myelopoiesis Neoplasm Proteins SOXC Transcription Factors Zebrafish Zebrafish Proteins Lu, J.-W Hsieh, M.-S Hou, H.-A Chen, C.-Y Tien, H.-F Lin, L.-I Overexpression of SOX4 correlates with poor prognosis of acute myeloid leukemia and is leukemogenic in zebrafish
description	10.1038/bcj.2017.74
author2	BIOLOGICAL SCIENCES
author_facet	BIOLOGICAL SCIENCES Lu, J.-W Hsieh, M.-S Hou, H.-A Chen, C.-Y Tien, H.-F Lin, L.-I
format	Article
author	Lu, J.-W Hsieh, M.-S Hou, H.-A Chen, C.-Y Tien, H.-F Lin, L.-I
author_sort	Lu, J.-W
title	Overexpression of SOX4 correlates with poor prognosis of acute myeloid leukemia and is leukemogenic in zebrafish
title_short	Overexpression of SOX4 correlates with poor prognosis of acute myeloid leukemia and is leukemogenic in zebrafish
title_full	Overexpression of SOX4 correlates with poor prognosis of acute myeloid leukemia and is leukemogenic in zebrafish
title_fullStr	Overexpression of SOX4 correlates with poor prognosis of acute myeloid leukemia and is leukemogenic in zebrafish
title_full_unstemmed	Overexpression of SOX4 correlates with poor prognosis of acute myeloid leukemia and is leukemogenic in zebrafish
title_sort	overexpression of sox4 correlates with poor prognosis of acute myeloid leukemia and is leukemogenic in zebrafish
publisher	Nature Publishing Group
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/179702
_version_	1795374484928069632

Overexpression of SOX4 correlates with poor prognosis of acute myeloid leukemia and is leukemogenic in zebrafish

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