Preventing tissue fibrosis by local biomaterials interfacing of specific cryptic extracellular matrix information

Preventing tissue fibrosis by local biomaterials interfacing of specific cryptic extracellular matrix information

10.1038/ncomms15509

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Bibliographic Details
Main Authors:	Horejs, C.-M, St-Pierre, J.-P, Ojala, J.R.M, Steele, J.A.M, Da Silva, P.B, Rynne-Vidal, A, Maynard, S.A, Hansel, C.S, Rodríguez-Fernández, C, Mazo, M.M, You, A.Y.F, Wang, A.J, Von Erlach, T, Tryggvason, K, López-Cabrera, M, Stevens, M.M
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	Acta2 protein alpha3 integrin beta1 integrin biomaterial cadherin cadherin 2 cell protein Col1a1 protein Fn1 protein gelatinase A gelatinase B laminin 1 laminin 1 beta transcription factor Slug transcription factor Snail transforming growth factor beta1 unclassified drug laminin protein binding very late activation antigen 3 anatomy cells and cell components gene gene expression hormone protein rodent animal cell animal experiment animal model animal tissue Article basement membrane confocal microscopy controlled study drug delivery system electrospinning enzyme inhibition epithelial mesenchymal transition ex vivo study extracellular matrix female fluorescence microscopy HEK293 cell line human human cell in vivo study incubation time male mesothelium mouse nanofabrication nonhuman peritoneal fibrosis protein content protein function protein protein interaction Raman spectrometry signal transduction tissue structure total internal reflection fluorescence microscopy upregulation animal artificial membrane chemistry cytology disease model epithelium epithelium cell gene expression profiling genetics mammary gland metabolism pathology peritoneum Animals Biocompatible Materials Disease Models, Animal Epithelial Cells Epithelial-Mesenchymal Transition Epithelium Extracellular Matrix Gene Expression Profiling HEK293 Cells Humans Integrin alpha3beta1 Laminin Mammary Glands, Human Matrix Metalloproteinase 2 Membranes, Artificial Mice Peritoneal Fibrosis Peritoneum Protein Binding Signal Transduction
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/179712
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Institution:	National University of Singapore

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