Chrysophanic acid reduces testosterone-induced benign prostatic hyperplasia in rats by suppressing 5?-reductase and extracellular signal-regulated kinase

• Main Authors: Youn, D.-H, Park, J, Kim, H.-L, Jung, Y, Kang, J, Jeong, M.-Y, Sethi, G, Ahn, K.S, Um, J.-Y
• Other Authors: DEPT OF PHARMACOLOGY
• Format: Article
• Published: Impact Journals LLC 2020
• Subjects: androgen receptor; chrysophanic acid; estrogen receptor alpha; finasteride; mitogen activated protein kinase; mitogen activated protein kinase p38; prostate specific antigen; steroid 5alpha reductase; steroid receptor coactivator 1; stress activated protein kinase; testosterone propionate; animal experiment; animal model; animal tissue; antigen expression; antiproliferative activity; Article; cell proliferation; controlled study; down regulation; drug effect; enzyme inhibition; enzyme repression; histology; human; human cell; in vitro study; male; nonhuman; prostate epithelium cell; prostate hypertrophy; prostate weight; protein expression; rat; upregulation
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/179769
• Institution: National University of Singapore

10.18632/oncotarget.13430