Chrysophanic acid reduces testosterone-induced benign prostatic hyperplasia in rats by suppressing 5?-reductase and extracellular signal-regulated kinase

10.18632/oncotarget.13430

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Main Authors:	Youn, D.-H, Park, J, Kim, H.-L, Jung, Y, Kang, J, Jeong, M.-Y, Sethi, G, Ahn, K.S, Um, J.-Y
Other Authors:	PHARMACOLOGY
Format:	Article
Published:	Impact Journals LLC 2020
Subjects:	androgen receptor chrysophanic acid estrogen receptor alpha finasteride mitogen activated protein kinase mitogen activated protein kinase p38 prostate specific antigen steroid 5alpha reductase steroid receptor coactivator 1 stress activated protein kinase testosterone propionate animal experiment animal model animal tissue antigen expression antiproliferative activity Article cell proliferation controlled study down regulation drug effect enzyme inhibition enzyme repression histology human human cell in vitro study male nonhuman prostate epithelium cell prostate hypertrophy prostate weight protein expression rat upregulation
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/179769
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1797692024-11-12T00:37:19Z Chrysophanic acid reduces testosterone-induced benign prostatic hyperplasia in rats by suppressing 5?-reductase and extracellular signal-regulated kinase Youn, D.-H Park, J Kim, H.-L Jung, Y Kang, J Jeong, M.-Y Sethi, G Ahn, K.S Um, J.-Y PHARMACOLOGY androgen receptor chrysophanic acid estrogen receptor alpha finasteride mitogen activated protein kinase mitogen activated protein kinase p38 prostate specific antigen steroid 5alpha reductase steroid receptor coactivator 1 stress activated protein kinase testosterone propionate animal experiment animal model animal tissue antigen expression antiproliferative activity Article cell proliferation controlled study down regulation drug effect enzyme inhibition enzyme repression histology human human cell in vitro study male nonhuman prostate epithelium cell prostate hypertrophy prostate weight protein expression rat upregulation 10.18632/oncotarget.13430 Oncotarget 8 6 9500-9512 2020-10-26T03:02:05Z 2020-10-26T03:02:05Z 2017 Article Youn, D.-H, Park, J, Kim, H.-L, Jung, Y, Kang, J, Jeong, M.-Y, Sethi, G, Ahn, K.S, Um, J.-Y (2017). Chrysophanic acid reduces testosterone-induced benign prostatic hyperplasia in rats by suppressing 5?-reductase and extracellular signal-regulated kinase. Oncotarget 8 (6) : 9500-9512. ScholarBank@NUS Repository. https://doi.org/10.18632/oncotarget.13430 1949-2553 https://scholarbank.nus.edu.sg/handle/10635/179769 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Impact Journals LLC Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	androgen receptor chrysophanic acid estrogen receptor alpha finasteride mitogen activated protein kinase mitogen activated protein kinase p38 prostate specific antigen steroid 5alpha reductase steroid receptor coactivator 1 stress activated protein kinase testosterone propionate animal experiment animal model animal tissue antigen expression antiproliferative activity Article cell proliferation controlled study down regulation drug effect enzyme inhibition enzyme repression histology human human cell in vitro study male nonhuman prostate epithelium cell prostate hypertrophy prostate weight protein expression rat upregulation
spellingShingle	androgen receptor chrysophanic acid estrogen receptor alpha finasteride mitogen activated protein kinase mitogen activated protein kinase p38 prostate specific antigen steroid 5alpha reductase steroid receptor coactivator 1 stress activated protein kinase testosterone propionate animal experiment animal model animal tissue antigen expression antiproliferative activity Article cell proliferation controlled study down regulation drug effect enzyme inhibition enzyme repression histology human human cell in vitro study male nonhuman prostate epithelium cell prostate hypertrophy prostate weight protein expression rat upregulation Youn, D.-H Park, J Kim, H.-L Jung, Y Kang, J Jeong, M.-Y Sethi, G Ahn, K.S Um, J.-Y Chrysophanic acid reduces testosterone-induced benign prostatic hyperplasia in rats by suppressing 5?-reductase and extracellular signal-regulated kinase
description	10.18632/oncotarget.13430
author2	PHARMACOLOGY
author_facet	PHARMACOLOGY Youn, D.-H Park, J Kim, H.-L Jung, Y Kang, J Jeong, M.-Y Sethi, G Ahn, K.S Um, J.-Y
format	Article
author	Youn, D.-H Park, J Kim, H.-L Jung, Y Kang, J Jeong, M.-Y Sethi, G Ahn, K.S Um, J.-Y
author_sort	Youn, D.-H
title	Chrysophanic acid reduces testosterone-induced benign prostatic hyperplasia in rats by suppressing 5?-reductase and extracellular signal-regulated kinase
title_short	Chrysophanic acid reduces testosterone-induced benign prostatic hyperplasia in rats by suppressing 5?-reductase and extracellular signal-regulated kinase
title_full	Chrysophanic acid reduces testosterone-induced benign prostatic hyperplasia in rats by suppressing 5?-reductase and extracellular signal-regulated kinase
title_fullStr	Chrysophanic acid reduces testosterone-induced benign prostatic hyperplasia in rats by suppressing 5?-reductase and extracellular signal-regulated kinase
title_full_unstemmed	Chrysophanic acid reduces testosterone-induced benign prostatic hyperplasia in rats by suppressing 5?-reductase and extracellular signal-regulated kinase
title_sort	chrysophanic acid reduces testosterone-induced benign prostatic hyperplasia in rats by suppressing 5?-reductase and extracellular signal-regulated kinase
publisher	Impact Journals LLC
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/179769
_version_	1821198233653739520

Chrysophanic acid reduces testosterone-induced benign prostatic hyperplasia in rats by suppressing 5?-reductase and extracellular signal-regulated kinase

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