Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels

• Main Authors: Li, G.-B, Fu, R.-Q, Shen, H.-M, Zhou, J, Hu, X.-Y, Liu, Y.-X, Li, Y.-N, Zhang, H.-W, Liu, X, Zhang, Y.-H, Huang, C, Zhang, R, Gao, N
• Other Authors: PHYSIOLOGY
• Format: Article
• Published: Impact Journals LLC 2020
• Subjects: cell protein; LC3B II protein; mitochondrial protein; polyphyllin I; protein PARK2; PTEN induced putative kinase 1; sequestosome 1; tumor protein; ubiquitin; unclassified drug; animal experiment; animal model; animal tissue; apoptosis; Article; breast cancer cell line; cancer inhibition; controlled study; female; fragmentation reaction; human; human cell; mitochondrial membrane potential; mitophagy; mouse; nonhuman; protein dephosphorylation; signal transduction; tumor xenograft
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/179771
• Institution: National University of Singapore

10.18632/oncotarget.14413