Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels

10.18632/oncotarget.14413

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Main Authors:	Li, G.-B, Fu, R.-Q, Shen, H.-M, Zhou, J, Hu, X.-Y, Liu, Y.-X, Li, Y.-N, Zhang, H.-W, Liu, X, Zhang, Y.-H, Huang, C, Zhang, R, Gao, N
Other Authors:	PHYSIOLOGY
Format:	Article
Published:	Impact Journals LLC 2020
Subjects:	cell protein LC3B II protein mitochondrial protein polyphyllin I protein PARK2 PTEN induced putative kinase 1 sequestosome 1 tumor protein ubiquitin unclassified drug animal experiment animal model animal tissue apoptosis Article breast cancer cell line cancer inhibition controlled study female fragmentation reaction human human cell mitochondrial membrane potential mitophagy mouse nonhuman protein dephosphorylation signal transduction tumor xenograft
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/179771
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1797712024-04-04T01:07:11Z Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels Li, G.-B Fu, R.-Q Shen, H.-M Zhou, J Hu, X.-Y Liu, Y.-X Li, Y.-N Zhang, H.-W Liu, X Zhang, Y.-H Huang, C Zhang, R Gao, N PHYSIOLOGY cell protein LC3B II protein mitochondrial protein polyphyllin I protein PARK2 PTEN induced putative kinase 1 sequestosome 1 tumor protein ubiquitin unclassified drug animal experiment animal model animal tissue apoptosis Article breast cancer cell line cancer inhibition controlled study female fragmentation reaction human human cell mitochondrial membrane potential mitophagy mouse nonhuman protein dephosphorylation signal transduction tumor xenograft 10.18632/oncotarget.14413 Oncotarget 8 6 10359-10374 2020-10-26T03:02:56Z 2020-10-26T03:02:56Z 2017 Article Li, G.-B, Fu, R.-Q, Shen, H.-M, Zhou, J, Hu, X.-Y, Liu, Y.-X, Li, Y.-N, Zhang, H.-W, Liu, X, Zhang, Y.-H, Huang, C, Zhang, R, Gao, N (2017). Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels. Oncotarget 8 (6) : 10359-10374. ScholarBank@NUS Repository. https://doi.org/10.18632/oncotarget.14413 1949-2553 https://scholarbank.nus.edu.sg/handle/10635/179771 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Impact Journals LLC Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	cell protein LC3B II protein mitochondrial protein polyphyllin I protein PARK2 PTEN induced putative kinase 1 sequestosome 1 tumor protein ubiquitin unclassified drug animal experiment animal model animal tissue apoptosis Article breast cancer cell line cancer inhibition controlled study female fragmentation reaction human human cell mitochondrial membrane potential mitophagy mouse nonhuman protein dephosphorylation signal transduction tumor xenograft
spellingShingle	cell protein LC3B II protein mitochondrial protein polyphyllin I protein PARK2 PTEN induced putative kinase 1 sequestosome 1 tumor protein ubiquitin unclassified drug animal experiment animal model animal tissue apoptosis Article breast cancer cell line cancer inhibition controlled study female fragmentation reaction human human cell mitochondrial membrane potential mitophagy mouse nonhuman protein dephosphorylation signal transduction tumor xenograft Li, G.-B Fu, R.-Q Shen, H.-M Zhou, J Hu, X.-Y Liu, Y.-X Li, Y.-N Zhang, H.-W Liu, X Zhang, Y.-H Huang, C Zhang, R Gao, N Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels
description	10.18632/oncotarget.14413
author2	PHYSIOLOGY
author_facet	PHYSIOLOGY Li, G.-B Fu, R.-Q Shen, H.-M Zhou, J Hu, X.-Y Liu, Y.-X Li, Y.-N Zhang, H.-W Liu, X Zhang, Y.-H Huang, C Zhang, R Gao, N
format	Article
author	Li, G.-B Fu, R.-Q Shen, H.-M Zhou, J Hu, X.-Y Liu, Y.-X Li, Y.-N Zhang, H.-W Liu, X Zhang, Y.-H Huang, C Zhang, R Gao, N
author_sort	Li, G.-B
title	Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels
title_short	Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels
title_full	Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels
title_fullStr	Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels
title_full_unstemmed	Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels
title_sort	polyphyllin i induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial pink1 levels
publisher	Impact Journals LLC
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/179771
_version_	1795374486771466240

Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels

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