Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network

10.1186/s13073-016-0329-5

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Main Authors: Richard, A.C, Peters, J.E, Lee, J.C, Vahedi, G, Schäffer, A.A, Siegel, R.M, Lyons, P.A, Smith, K.G.C
Other Authors: MEDICINE
Format: Article
Published: 2020
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/179921
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spelling sg-nus-scholar.10635-1799212024-04-18T03:08:14Z Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network Richard, A.C Peters, J.E Lee, J.C Vahedi, G Schäffer, A.A Siegel, R.M Lyons, P.A Smith, K.G.C MEDICINE tumor necrosis factor tumor necrosis factor receptor chromatin isoprotein tumor necrosis factor tumor necrosis factor receptor Article autoimmune disease autoinflammatory disease CD4+ T lymphocyte CD8+ T lymphocyte chromatin controlled study enhancer region gene expression genetic marker genetic variability genome-wide association study genomics human human cell leukocyte monocyte neutrophil priority journal quantitative trait locus single nucleotide polymorphism allele Autoimmune Diseases chemistry gene expression regulation gene regulatory network genetic predisposition genetics Hereditary Autoinflammatory Diseases human genome immunology mononuclear cell pathology quantitative trait locus risk signal transduction Alleles Autoimmune Diseases Chromatin Gene Expression Regulation Gene Regulatory Networks Genetic Predisposition to Disease Genome, Human Genome-Wide Association Study Hereditary Autoinflammatory Diseases Humans Leukocytes, Mononuclear Protein Isoforms Quantitative Trait Loci Receptors, Tumor Necrosis Factor Risk Signal Transduction Tumor Necrosis Factor-alpha 10.1186/s13073-016-0329-5 Genome Medicine 8 1 76 2020-10-26T05:06:53Z 2020-10-26T05:06:53Z 2016 Article Richard, A.C, Peters, J.E, Lee, J.C, Vahedi, G, Schäffer, A.A, Siegel, R.M, Lyons, P.A, Smith, K.G.C (2016). Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network. Genome Medicine 8 (1) : 76. ScholarBank@NUS Repository. https://doi.org/10.1186/s13073-016-0329-5 1756994X https://scholarbank.nus.edu.sg/handle/10635/179921 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic tumor necrosis factor
tumor necrosis factor receptor
chromatin
isoprotein
tumor necrosis factor
tumor necrosis factor receptor
Article
autoimmune disease
autoinflammatory disease
CD4+ T lymphocyte
CD8+ T lymphocyte
chromatin
controlled study
enhancer region
gene expression
genetic marker
genetic variability
genome-wide association study
genomics
human
human cell
leukocyte
monocyte
neutrophil
priority journal
quantitative trait locus
single nucleotide polymorphism
allele
Autoimmune Diseases
chemistry
gene expression regulation
gene regulatory network
genetic predisposition
genetics
Hereditary Autoinflammatory Diseases
human genome
immunology
mononuclear cell
pathology
quantitative trait locus
risk
signal transduction
Alleles
Autoimmune Diseases
Chromatin
Gene Expression Regulation
Gene Regulatory Networks
Genetic Predisposition to Disease
Genome, Human
Genome-Wide Association Study
Hereditary Autoinflammatory Diseases
Humans
Leukocytes, Mononuclear
Protein Isoforms
Quantitative Trait Loci
Receptors, Tumor Necrosis Factor
Risk
Signal Transduction
Tumor Necrosis Factor-alpha
spellingShingle tumor necrosis factor
tumor necrosis factor receptor
chromatin
isoprotein
tumor necrosis factor
tumor necrosis factor receptor
Article
autoimmune disease
autoinflammatory disease
CD4+ T lymphocyte
CD8+ T lymphocyte
chromatin
controlled study
enhancer region
gene expression
genetic marker
genetic variability
genome-wide association study
genomics
human
human cell
leukocyte
monocyte
neutrophil
priority journal
quantitative trait locus
single nucleotide polymorphism
allele
Autoimmune Diseases
chemistry
gene expression regulation
gene regulatory network
genetic predisposition
genetics
Hereditary Autoinflammatory Diseases
human genome
immunology
mononuclear cell
pathology
quantitative trait locus
risk
signal transduction
Alleles
Autoimmune Diseases
Chromatin
Gene Expression Regulation
Gene Regulatory Networks
Genetic Predisposition to Disease
Genome, Human
Genome-Wide Association Study
Hereditary Autoinflammatory Diseases
Humans
Leukocytes, Mononuclear
Protein Isoforms
Quantitative Trait Loci
Receptors, Tumor Necrosis Factor
Risk
Signal Transduction
Tumor Necrosis Factor-alpha
Richard, A.C
Peters, J.E
Lee, J.C
Vahedi, G
Schäffer, A.A
Siegel, R.M
Lyons, P.A
Smith, K.G.C
Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network
description 10.1186/s13073-016-0329-5
author2 MEDICINE
author_facet MEDICINE
Richard, A.C
Peters, J.E
Lee, J.C
Vahedi, G
Schäffer, A.A
Siegel, R.M
Lyons, P.A
Smith, K.G.C
format Article
author Richard, A.C
Peters, J.E
Lee, J.C
Vahedi, G
Schäffer, A.A
Siegel, R.M
Lyons, P.A
Smith, K.G.C
author_sort Richard, A.C
title Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network
title_short Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network
title_full Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network
title_fullStr Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network
title_full_unstemmed Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network
title_sort targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the tnf superfamily cytokine signalling network
publishDate 2020
url https://scholarbank.nus.edu.sg/handle/10635/179921
_version_ 1800914573160611840