Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network
10.1186/s13073-016-0329-5
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sg-nus-scholar.10635-1799212024-04-18T03:08:14Z Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network Richard, A.C Peters, J.E Lee, J.C Vahedi, G Schäffer, A.A Siegel, R.M Lyons, P.A Smith, K.G.C MEDICINE tumor necrosis factor tumor necrosis factor receptor chromatin isoprotein tumor necrosis factor tumor necrosis factor receptor Article autoimmune disease autoinflammatory disease CD4+ T lymphocyte CD8+ T lymphocyte chromatin controlled study enhancer region gene expression genetic marker genetic variability genome-wide association study genomics human human cell leukocyte monocyte neutrophil priority journal quantitative trait locus single nucleotide polymorphism allele Autoimmune Diseases chemistry gene expression regulation gene regulatory network genetic predisposition genetics Hereditary Autoinflammatory Diseases human genome immunology mononuclear cell pathology quantitative trait locus risk signal transduction Alleles Autoimmune Diseases Chromatin Gene Expression Regulation Gene Regulatory Networks Genetic Predisposition to Disease Genome, Human Genome-Wide Association Study Hereditary Autoinflammatory Diseases Humans Leukocytes, Mononuclear Protein Isoforms Quantitative Trait Loci Receptors, Tumor Necrosis Factor Risk Signal Transduction Tumor Necrosis Factor-alpha 10.1186/s13073-016-0329-5 Genome Medicine 8 1 76 2020-10-26T05:06:53Z 2020-10-26T05:06:53Z 2016 Article Richard, A.C, Peters, J.E, Lee, J.C, Vahedi, G, Schäffer, A.A, Siegel, R.M, Lyons, P.A, Smith, K.G.C (2016). Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network. Genome Medicine 8 (1) : 76. ScholarBank@NUS Repository. https://doi.org/10.1186/s13073-016-0329-5 1756994X https://scholarbank.nus.edu.sg/handle/10635/179921 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031 |
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tumor necrosis factor tumor necrosis factor receptor chromatin isoprotein tumor necrosis factor tumor necrosis factor receptor Article autoimmune disease autoinflammatory disease CD4+ T lymphocyte CD8+ T lymphocyte chromatin controlled study enhancer region gene expression genetic marker genetic variability genome-wide association study genomics human human cell leukocyte monocyte neutrophil priority journal quantitative trait locus single nucleotide polymorphism allele Autoimmune Diseases chemistry gene expression regulation gene regulatory network genetic predisposition genetics Hereditary Autoinflammatory Diseases human genome immunology mononuclear cell pathology quantitative trait locus risk signal transduction Alleles Autoimmune Diseases Chromatin Gene Expression Regulation Gene Regulatory Networks Genetic Predisposition to Disease Genome, Human Genome-Wide Association Study Hereditary Autoinflammatory Diseases Humans Leukocytes, Mononuclear Protein Isoforms Quantitative Trait Loci Receptors, Tumor Necrosis Factor Risk Signal Transduction Tumor Necrosis Factor-alpha |
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tumor necrosis factor tumor necrosis factor receptor chromatin isoprotein tumor necrosis factor tumor necrosis factor receptor Article autoimmune disease autoinflammatory disease CD4+ T lymphocyte CD8+ T lymphocyte chromatin controlled study enhancer region gene expression genetic marker genetic variability genome-wide association study genomics human human cell leukocyte monocyte neutrophil priority journal quantitative trait locus single nucleotide polymorphism allele Autoimmune Diseases chemistry gene expression regulation gene regulatory network genetic predisposition genetics Hereditary Autoinflammatory Diseases human genome immunology mononuclear cell pathology quantitative trait locus risk signal transduction Alleles Autoimmune Diseases Chromatin Gene Expression Regulation Gene Regulatory Networks Genetic Predisposition to Disease Genome, Human Genome-Wide Association Study Hereditary Autoinflammatory Diseases Humans Leukocytes, Mononuclear Protein Isoforms Quantitative Trait Loci Receptors, Tumor Necrosis Factor Risk Signal Transduction Tumor Necrosis Factor-alpha Richard, A.C Peters, J.E Lee, J.C Vahedi, G Schäffer, A.A Siegel, R.M Lyons, P.A Smith, K.G.C Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network |
description |
10.1186/s13073-016-0329-5 |
author2 |
MEDICINE |
author_facet |
MEDICINE Richard, A.C Peters, J.E Lee, J.C Vahedi, G Schäffer, A.A Siegel, R.M Lyons, P.A Smith, K.G.C |
format |
Article |
author |
Richard, A.C Peters, J.E Lee, J.C Vahedi, G Schäffer, A.A Siegel, R.M Lyons, P.A Smith, K.G.C |
author_sort |
Richard, A.C |
title |
Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network |
title_short |
Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network |
title_full |
Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network |
title_fullStr |
Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network |
title_full_unstemmed |
Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network |
title_sort |
targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the tnf superfamily cytokine signalling network |
publishDate |
2020 |
url |
https://scholarbank.nus.edu.sg/handle/10635/179921 |
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1800914573160611840 |