Targeted Inhibition of the MIR-199a/214 Cluster by CRISPR Interference Augments the Tumor Tropism of Human Induced Pluripotent Stem Cell-Derived Neural Stem Cells under Hypoxic Condition

Targeted Inhibition of the MIR-199a/214 Cluster by CRISPR Interference Augments the Tumor Tropism of Human Induced Pluripotent Stem Cell-Derived Neural Stem Cells under Hypoxic Condition

10.1155/2016/3598542

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Bibliographic Details
Main Authors: Luo, Y, Xu, X, An, X, Sun, X, Wang, S, Zhu, D
Other Authors: BIOLOGY (NU)
Format: Article
Published: 2020
Subjects:
hypoxia inducible factor 1alpha
microRNA
microRNA 199a
microRNA 199a 3p
microRNA 199a 5p
microRNA 214
mitogen activated protein kinase 1
scatter factor receptor
unclassified drug
animal cell
animal experiment
animal model
Article
cell hypoxia
cell migration
clustered regularly interspaced short palindromic repeat
controlled study
female
gene cluster
gene expression
human
human cell
in vitro study
in vivo study
induced pluripotent stem cell
mouse
neural stem cell
nonhuman
promoter region
tropism
upregulation
Online Access:https://scholarbank.nus.edu.sg/handle/10635/179957
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Institution: National University of Singapore

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