Role of the MPTP in conditioning the heart - Translatability and mechanism

• Main Authors: Ong, S.-B, Dongworth, R.K, Cabrera-Fuentes, H.A, Hausenloy, D.J
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Review
• Published: John Wiley and Sons Inc. 2020
• Subjects: aldehyde dehydrogenase isoenzyme 2; calcineurin; cyclosporin A; cytochrome c; mitochondrial permeability transition pore; protein kinase C epsilon; STAT3 protein; tumor necrosis factor alpha; carrier protein; acute heart infarction; alkalinization; apoptosis; calcium cell level; cardiovascular response; cell death; cell growth; cell pH; cell protection; clinical trial (topic); coronary artery bypass graft; drug efficacy; drug mechanism; electron transport; heart infarction; heart infarction size; heart muscle cell; heart muscle ischemia; heart muscle reperfusion; heart muscle revascularization; heart protection; human; mitochondrial membrane; nonhuman; oxidative stress; priority journal; protein function; protein phosphorylation; protein targeting; reperfusion injury; Review; ST segment elevation myocardial infarction; animal; antagonists and inhibitors; cardiac muscle; heart infarction prevention; metabolism; Myocardial Reperfusion Injury; Animals; Humans; Ischemic Preconditioning, Myocardial; Mitochondrial Membrane Transport Proteins; Myocardium
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/180082
• Institution: National University of Singapore

10.1111/bph.13013