MicroRNA miR-124 controls the choice between neuronal and astrocyte differentiation by fine-tuning Ezh2 expression

• Main Authors: Neo, W.H, Yap, K, Lee, S.H, Looi, L.S, Khandelia, P, Neo, S.X, Makeyev, E.V, Su, I.-H
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: American Society for Biochemistry and Molecular Biology Inc. 2020
• Subjects: Gene expression; RNA; Stem cells; Histone methyltransferase; Molecular mechanism; Neural stem cell; Neuroblastoma cells; Neuronal differentiation; Polycomb group proteins; Regulatory program; Untranslated regions; Neurons; 3' untranslated region; EZH2 protein, human; Ezh2 protein, mouse; microRNA; MIRN124 microRNA, human; Mirn124 microRNA, mouse; polycomb repressive complex 2; animal; astrocyte; biosynthesis; cell differentiation; cytology; gene expression regulation; genetics; HEK293 cell line; human; metabolism; mouse; nerve cell; physiology; tumor cell line; 3' Untranslated Regions; Animals; Astrocytes; Cell Differentiation; Cell Line, Tumor; Gene Expression Regulation; HEK293 Cells; Humans; Mice; MicroRNAs; Polycomb Repressive Complex 2
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/180141
• Institution: National University of Singapore

10.1074/jbc.M113.525493