MicroRNA miR-124 controls the choice between neuronal and astrocyte differentiation by fine-tuning Ezh2 expression

10.1074/jbc.M113.525493

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Main Authors: Neo, W.H, Yap, K, Lee, S.H, Looi, L.S, Khandelia, P, Neo, S.X, Makeyev, E.V, Su, I.-H
Other Authors: DUKE-NUS MEDICAL SCHOOL
Format: Article
Published: American Society for Biochemistry and Molecular Biology Inc. 2020
Subjects:
RNA
Online Access:https://scholarbank.nus.edu.sg/handle/10635/180141
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spelling sg-nus-scholar.10635-1801412023-11-01T08:49:13Z MicroRNA miR-124 controls the choice between neuronal and astrocyte differentiation by fine-tuning Ezh2 expression Neo, W.H Yap, K Lee, S.H Looi, L.S Khandelia, P Neo, S.X Makeyev, E.V Su, I.-H DUKE-NUS MEDICAL SCHOOL Gene expression RNA Stem cells Histone methyltransferase Molecular mechanism Neural stem cell Neuroblastoma cells Neuronal differentiation Polycomb group proteins Regulatory program Untranslated regions Neurons 3' untranslated region EZH2 protein, human Ezh2 protein, mouse microRNA MIRN124 microRNA, human Mirn124 microRNA, mouse polycomb repressive complex 2 3' untranslated region animal astrocyte biosynthesis cell differentiation cytology gene expression regulation genetics HEK293 cell line human metabolism mouse nerve cell physiology tumor cell line 3' Untranslated Regions Animals Astrocytes Cell Differentiation Cell Line, Tumor Gene Expression Regulation HEK293 Cells Humans Mice MicroRNAs Neurons Polycomb Repressive Complex 2 10.1074/jbc.M113.525493 Journal of Biological Chemistry 289 30 20788-20801 2020-10-26T07:11:55Z 2020-10-26T07:11:55Z 2014 Article Neo, W.H, Yap, K, Lee, S.H, Looi, L.S, Khandelia, P, Neo, S.X, Makeyev, E.V, Su, I.-H (2014). MicroRNA miR-124 controls the choice between neuronal and astrocyte differentiation by fine-tuning Ezh2 expression. Journal of Biological Chemistry 289 (30) : 20788-20801. ScholarBank@NUS Repository. https://doi.org/10.1074/jbc.M113.525493 0021-9258 https://scholarbank.nus.edu.sg/handle/10635/180141 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ American Society for Biochemistry and Molecular Biology Inc. Unpaywall 20201031
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic Gene expression
RNA
Stem cells
Histone methyltransferase
Molecular mechanism
Neural stem cell
Neuroblastoma cells
Neuronal differentiation
Polycomb group proteins
Regulatory program
Untranslated regions
Neurons
3' untranslated region
EZH2 protein, human
Ezh2 protein, mouse
microRNA
MIRN124 microRNA, human
Mirn124 microRNA, mouse
polycomb repressive complex 2
3' untranslated region
animal
astrocyte
biosynthesis
cell differentiation
cytology
gene expression regulation
genetics
HEK293 cell line
human
metabolism
mouse
nerve cell
physiology
tumor cell line
3' Untranslated Regions
Animals
Astrocytes
Cell Differentiation
Cell Line, Tumor
Gene Expression Regulation
HEK293 Cells
Humans
Mice
MicroRNAs
Neurons
Polycomb Repressive Complex 2
spellingShingle Gene expression
RNA
Stem cells
Histone methyltransferase
Molecular mechanism
Neural stem cell
Neuroblastoma cells
Neuronal differentiation
Polycomb group proteins
Regulatory program
Untranslated regions
Neurons
3' untranslated region
EZH2 protein, human
Ezh2 protein, mouse
microRNA
MIRN124 microRNA, human
Mirn124 microRNA, mouse
polycomb repressive complex 2
3' untranslated region
animal
astrocyte
biosynthesis
cell differentiation
cytology
gene expression regulation
genetics
HEK293 cell line
human
metabolism
mouse
nerve cell
physiology
tumor cell line
3' Untranslated Regions
Animals
Astrocytes
Cell Differentiation
Cell Line, Tumor
Gene Expression Regulation
HEK293 Cells
Humans
Mice
MicroRNAs
Neurons
Polycomb Repressive Complex 2
Neo, W.H
Yap, K
Lee, S.H
Looi, L.S
Khandelia, P
Neo, S.X
Makeyev, E.V
Su, I.-H
MicroRNA miR-124 controls the choice between neuronal and astrocyte differentiation by fine-tuning Ezh2 expression
description 10.1074/jbc.M113.525493
author2 DUKE-NUS MEDICAL SCHOOL
author_facet DUKE-NUS MEDICAL SCHOOL
Neo, W.H
Yap, K
Lee, S.H
Looi, L.S
Khandelia, P
Neo, S.X
Makeyev, E.V
Su, I.-H
format Article
author Neo, W.H
Yap, K
Lee, S.H
Looi, L.S
Khandelia, P
Neo, S.X
Makeyev, E.V
Su, I.-H
author_sort Neo, W.H
title MicroRNA miR-124 controls the choice between neuronal and astrocyte differentiation by fine-tuning Ezh2 expression
title_short MicroRNA miR-124 controls the choice between neuronal and astrocyte differentiation by fine-tuning Ezh2 expression
title_full MicroRNA miR-124 controls the choice between neuronal and astrocyte differentiation by fine-tuning Ezh2 expression
title_fullStr MicroRNA miR-124 controls the choice between neuronal and astrocyte differentiation by fine-tuning Ezh2 expression
title_full_unstemmed MicroRNA miR-124 controls the choice between neuronal and astrocyte differentiation by fine-tuning Ezh2 expression
title_sort microrna mir-124 controls the choice between neuronal and astrocyte differentiation by fine-tuning ezh2 expression
publisher American Society for Biochemistry and Molecular Biology Inc.
publishDate 2020
url https://scholarbank.nus.edu.sg/handle/10635/180141
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