KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro

10.1128/AAC.01927-13

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Main Authors:	Zeeman, A.-M, Van Amsterdam, S.M, McNamara, C.W, Voorberg-van Der Wel, A, Klooster, E.J, Van Den Berg, A, Remarque, E.J, Plouffe, D.M, Van Gemert, G.-J, Luty, A, Sauerwein, R, Gagaring, K, Borboa, R, Chen, Z, Kuhen, K, Glynne, R.J, Chatterjee, A.K, Nagle, A, Roland, J, Winzeler, E.A, Leroy, D, Campo, B, Diagana, T.T, Yeung, B.K.S, Thomas, A.W, Kocken, C.H.M
Other Authors:	MICROBIOLOGY AND IMMUNOLOGY
Format:	Article
Published:	2020
Subjects:	amodiaquine antibody antimalarial agent artesunate atovaquone benflumetol bulaquine chloroquine cycloheximide dihydroartemisinin doxycycline heat shock protein 70 kae 609 kaf 156 kai 407 mefloquine npc 1161b piperaquine primaquine proguanil tafenoquine unclassified drug animal cell animal experiment animal model antimalarial activity antimalarial drug susceptibility article body weight controlled study dilution drug efficacy drug potency drug structure female high throughput screening hypnozoite IC 50 in vitro study infection prevention liver cell low drug dose mouse nonhuman parasite development parasitemia plasmodium (life cycle stage) Plasmodium berghei infection Plasmodium cynomolgi Plasmodium vivax priority journal rhesus monkey schizont sporozoite Animals Antimalarials Drug Evaluation, Preclinical Female Hepatocytes Imidazoles Liver Macaca mulatta Malaria Mice Mice, Inbred ICR Pyrazines Sporozoites
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/180146
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1801462024-03-27T08:19:37Z KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro Zeeman, A.-M Van Amsterdam, S.M McNamara, C.W Voorberg-van Der Wel, A Klooster, E.J Van Den Berg, A Remarque, E.J Plouffe, D.M Van Gemert, G.-J Luty, A Sauerwein, R Gagaring, K Borboa, R Chen, Z Kuhen, K Glynne, R.J Chatterjee, A.K Nagle, A Roland, J Winzeler, E.A Leroy, D Campo, B Diagana, T.T Yeung, B.K.S Thomas, A.W Kocken, C.H.M MICROBIOLOGY AND IMMUNOLOGY amodiaquine antibody antimalarial agent artesunate atovaquone benflumetol bulaquine chloroquine cycloheximide dihydroartemisinin doxycycline heat shock protein 70 kae 609 kaf 156 kai 407 mefloquine npc 1161b piperaquine primaquine proguanil tafenoquine unclassified drug animal cell animal experiment animal model antimalarial activity antimalarial drug susceptibility article body weight controlled study dilution drug efficacy drug potency drug structure female high throughput screening hypnozoite IC 50 in vitro study infection prevention liver cell low drug dose mouse nonhuman parasite development parasitemia plasmodium (life cycle stage) Plasmodium berghei infection Plasmodium cynomolgi Plasmodium vivax priority journal rhesus monkey schizont sporozoite Animals Antimalarials Drug Evaluation, Preclinical Female Hepatocytes Imidazoles Liver Macaca mulatta Malaria Mice Mice, Inbred ICR Plasmodium cynomolgi Pyrazines Sporozoites 10.1128/AAC.01927-13 Antimicrobial Agents and Chemotherapy 58 3 1586-1595 2020-10-26T07:13:39Z 2020-10-26T07:13:39Z 2014 Article Zeeman, A.-M, Van Amsterdam, S.M, McNamara, C.W, Voorberg-van Der Wel, A, Klooster, E.J, Van Den Berg, A, Remarque, E.J, Plouffe, D.M, Van Gemert, G.-J, Luty, A, Sauerwein, R, Gagaring, K, Borboa, R, Chen, Z, Kuhen, K, Glynne, R.J, Chatterjee, A.K, Nagle, A, Roland, J, Winzeler, E.A, Leroy, D, Campo, B, Diagana, T.T, Yeung, B.K.S, Thomas, A.W, Kocken, C.H.M (2014). KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro. Antimicrobial Agents and Chemotherapy 58 (3) : 1586-1595. ScholarBank@NUS Repository. https://doi.org/10.1128/AAC.01927-13 0066-4804 https://scholarbank.nus.edu.sg/handle/10635/180146 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	amodiaquine antibody antimalarial agent artesunate atovaquone benflumetol bulaquine chloroquine cycloheximide dihydroartemisinin doxycycline heat shock protein 70 kae 609 kaf 156 kai 407 mefloquine npc 1161b piperaquine primaquine proguanil tafenoquine unclassified drug animal cell animal experiment animal model antimalarial activity antimalarial drug susceptibility article body weight controlled study dilution drug efficacy drug potency drug structure female high throughput screening hypnozoite IC 50 in vitro study infection prevention liver cell low drug dose mouse nonhuman parasite development parasitemia plasmodium (life cycle stage) Plasmodium berghei infection Plasmodium cynomolgi Plasmodium vivax priority journal rhesus monkey schizont sporozoite Animals Antimalarials Drug Evaluation, Preclinical Female Hepatocytes Imidazoles Liver Macaca mulatta Malaria Mice Mice, Inbred ICR Plasmodium cynomolgi Pyrazines Sporozoites
spellingShingle	amodiaquine antibody antimalarial agent artesunate atovaquone benflumetol bulaquine chloroquine cycloheximide dihydroartemisinin doxycycline heat shock protein 70 kae 609 kaf 156 kai 407 mefloquine npc 1161b piperaquine primaquine proguanil tafenoquine unclassified drug animal cell animal experiment animal model antimalarial activity antimalarial drug susceptibility article body weight controlled study dilution drug efficacy drug potency drug structure female high throughput screening hypnozoite IC 50 in vitro study infection prevention liver cell low drug dose mouse nonhuman parasite development parasitemia plasmodium (life cycle stage) Plasmodium berghei infection Plasmodium cynomolgi Plasmodium vivax priority journal rhesus monkey schizont sporozoite Animals Antimalarials Drug Evaluation, Preclinical Female Hepatocytes Imidazoles Liver Macaca mulatta Malaria Mice Mice, Inbred ICR Plasmodium cynomolgi Pyrazines Sporozoites Zeeman, A.-M Van Amsterdam, S.M McNamara, C.W Voorberg-van Der Wel, A Klooster, E.J Van Den Berg, A Remarque, E.J Plouffe, D.M Van Gemert, G.-J Luty, A Sauerwein, R Gagaring, K Borboa, R Chen, Z Kuhen, K Glynne, R.J Chatterjee, A.K Nagle, A Roland, J Winzeler, E.A Leroy, D Campo, B Diagana, T.T Yeung, B.K.S Thomas, A.W Kocken, C.H.M KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro
description	10.1128/AAC.01927-13
author2	MICROBIOLOGY AND IMMUNOLOGY
author_facet	MICROBIOLOGY AND IMMUNOLOGY Zeeman, A.-M Van Amsterdam, S.M McNamara, C.W Voorberg-van Der Wel, A Klooster, E.J Van Den Berg, A Remarque, E.J Plouffe, D.M Van Gemert, G.-J Luty, A Sauerwein, R Gagaring, K Borboa, R Chen, Z Kuhen, K Glynne, R.J Chatterjee, A.K Nagle, A Roland, J Winzeler, E.A Leroy, D Campo, B Diagana, T.T Yeung, B.K.S Thomas, A.W Kocken, C.H.M
format	Article
author	Zeeman, A.-M Van Amsterdam, S.M McNamara, C.W Voorberg-van Der Wel, A Klooster, E.J Van Den Berg, A Remarque, E.J Plouffe, D.M Van Gemert, G.-J Luty, A Sauerwein, R Gagaring, K Borboa, R Chen, Z Kuhen, K Glynne, R.J Chatterjee, A.K Nagle, A Roland, J Winzeler, E.A Leroy, D Campo, B Diagana, T.T Yeung, B.K.S Thomas, A.W Kocken, C.H.M
author_sort	Zeeman, A.-M
title	KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro
title_short	KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro
title_full	KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro
title_fullStr	KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro
title_full_unstemmed	KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro
title_sort	kai407, a potent non-8-aminoquinoline compound that kills plasmodium cynomolgi early dormant liver stage parasites in vitro
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/180146
_version_	1795301277447487488

KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro

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