Nuclear envelope-associated endosomes deliver surface proteins to the nucleus

Nuclear envelope-associated endosomes deliver surface proteins to the nucleus

10.1038/ncomms9218

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Bibliographic Details
Main Authors:	Chaumet, A, Wright, G.D, Seet, S.H, Tham, K.M, Gounko, N.V, Bard, F
Other Authors:	DEPT OF BIOCHEMISTRY
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	cell surface protein early endosome antigen 1 epidermal growth factor receptor histone H1 membrane protein nuclear protein protein disulfide isomerase Pseudomonas exotoxin SUN1 protein SUN2 protein translocon tubulin unclassified drug bacterial toxin exotoxin microtubule associated protein nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase nuclear localization signal SEC61A1 protein, human signal peptide SUN1 protein, human SUN2 protein, human toxA protein, Pseudomonas aeruginosa virulence factor bacterium cell organelle cells and cell components mobility protein RNA translocation Article cell fractionation cell nucleus cell nucleus membrane cell surface controlled study cytolysis cytosol cytosolic fraction electron microscopy endosome female Golgi complex HeLa cell line human human cell immunoprecipitation inner membrane nuclear import nuclear pore outer membrane protein binding protein localization protein transport regulatory mechanism RNA interference Western blotting confocal microscopy endocytosis endoplasmic reticulum fluorescent antibody technique gene silencing genetics metabolism tumor cell line Bacteria (microorganisms) ADP Ribose Transferases Bacterial Toxins Cell Line, Tumor Cell Nucleus Cytosol Endocytosis Endoplasmic Reticulum Endosomes Exotoxins Fluorescent Antibody Technique Gene Knockdown Techniques Golgi Apparatus HeLa Cells Humans Intracellular Signaling Peptides and Proteins Membrane Proteins Microscopy, Confocal Microscopy, Electron Microtubule-Associated Proteins Nuclear Envelope Nuclear Localization Signals Nuclear Proteins Protein Transport SEC Translocation Channels Virulence Factors
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/180439
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Institution:	National University of Singapore

Description
Summary:	10.1038/ncomms9218