Tropomodulin3 is a novel Akt2 effector regulating insulin-stimulated GLUT4 exocytosis through cortical actin remodeling

10.1038/ncomms6951

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Main Authors:	Lim, C.-Y, Bi, X, Wu, D, Kim, J.B, Gunning, P.W, Hong, W, Han, W
Other Authors:	INSTITUTE OF MOLECULAR & CELL BIOLOGY
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	actin binding protein actin capping protein F actin G actin glucose transporter 4 latrunculin B protein kinase B beta tropomodulin tropomodulin 3 unclassified drug actin AKT2 protein, human Akt2 protein, mouse glucose insulin protein kinase B SLC2A4 protein, human Slc2a4 protein, mouse TMOD3 protein, human Tmod3 protein, mouse cells and cell components chemical reaction membrane numerical model protein translocation actin filament adipocyte Article cross linking exocytosis glucose transport human human cell mass spectrometry protein interaction protein phosphorylation proteomics signal transduction 3T3 cell line animal C57BL mouse cell membrane fluorescence microscopy Lentivirinae male metabolism mouse phosphorylation thrombocyte 3T3-L1 Cells Actins Adipocytes Animals Blood Platelets Cell Membrane Exocytosis Glucose Glucose Transporter Type 4 Humans Insulin Lentivirus Male Mice Mice, Inbred C57BL Microscopy, Fluorescence Phosphorylation Proto-Oncogene Proteins c-akt Tropomodulin
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/180482
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1804822023-08-29T22:35:16Z Tropomodulin3 is a novel Akt2 effector regulating insulin-stimulated GLUT4 exocytosis through cortical actin remodeling Lim, C.-Y Bi, X Wu, D Kim, J.B Gunning, P.W Hong, W Han, W INSTITUTE OF MOLECULAR & CELL BIOLOGY DUKE-NUS MEDICAL SCHOOL actin binding protein actin capping protein F actin G actin glucose transporter 4 latrunculin B protein kinase B beta tropomodulin tropomodulin 3 unclassified drug actin AKT2 protein, human Akt2 protein, mouse glucose glucose transporter 4 insulin protein kinase B SLC2A4 protein, human Slc2a4 protein, mouse TMOD3 protein, human Tmod3 protein, mouse tropomodulin cells and cell components chemical reaction glucose membrane numerical model protein translocation actin filament adipocyte Article cross linking exocytosis glucose transport human human cell mass spectrometry protein interaction protein phosphorylation proteomics signal transduction 3T3 cell line animal C57BL mouse cell membrane exocytosis fluorescence microscopy Lentivirinae male metabolism mouse phosphorylation thrombocyte 3T3-L1 Cells Actins Adipocytes Animals Blood Platelets Cell Membrane Exocytosis Glucose Glucose Transporter Type 4 Humans Insulin Lentivirus Male Mice Mice, Inbred C57BL Microscopy, Fluorescence Phosphorylation Proto-Oncogene Proteins c-akt Tropomodulin 10.1038/ncomms6951 Nature Communications 6 6951 2020-10-26T09:10:38Z 2020-10-26T09:10:38Z 2015 Article Lim, C.-Y, Bi, X, Wu, D, Kim, J.B, Gunning, P.W, Hong, W, Han, W (2015). Tropomodulin3 is a novel Akt2 effector regulating insulin-stimulated GLUT4 exocytosis through cortical actin remodeling. Nature Communications 6 : 6951. ScholarBank@NUS Repository. https://doi.org/10.1038/ncomms6951 2041-1723 https://scholarbank.nus.edu.sg/handle/10635/180482 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Nature Publishing Group Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	actin binding protein actin capping protein F actin G actin glucose transporter 4 latrunculin B protein kinase B beta tropomodulin tropomodulin 3 unclassified drug actin AKT2 protein, human Akt2 protein, mouse glucose glucose transporter 4 insulin protein kinase B SLC2A4 protein, human Slc2a4 protein, mouse TMOD3 protein, human Tmod3 protein, mouse tropomodulin cells and cell components chemical reaction glucose membrane numerical model protein translocation actin filament adipocyte Article cross linking exocytosis glucose transport human human cell mass spectrometry protein interaction protein phosphorylation proteomics signal transduction 3T3 cell line animal C57BL mouse cell membrane exocytosis fluorescence microscopy Lentivirinae male metabolism mouse phosphorylation thrombocyte 3T3-L1 Cells Actins Adipocytes Animals Blood Platelets Cell Membrane Exocytosis Glucose Glucose Transporter Type 4 Humans Insulin Lentivirus Male Mice Mice, Inbred C57BL Microscopy, Fluorescence Phosphorylation Proto-Oncogene Proteins c-akt Tropomodulin
spellingShingle	actin binding protein actin capping protein F actin G actin glucose transporter 4 latrunculin B protein kinase B beta tropomodulin tropomodulin 3 unclassified drug actin AKT2 protein, human Akt2 protein, mouse glucose glucose transporter 4 insulin protein kinase B SLC2A4 protein, human Slc2a4 protein, mouse TMOD3 protein, human Tmod3 protein, mouse tropomodulin cells and cell components chemical reaction glucose membrane numerical model protein translocation actin filament adipocyte Article cross linking exocytosis glucose transport human human cell mass spectrometry protein interaction protein phosphorylation proteomics signal transduction 3T3 cell line animal C57BL mouse cell membrane exocytosis fluorescence microscopy Lentivirinae male metabolism mouse phosphorylation thrombocyte 3T3-L1 Cells Actins Adipocytes Animals Blood Platelets Cell Membrane Exocytosis Glucose Glucose Transporter Type 4 Humans Insulin Lentivirus Male Mice Mice, Inbred C57BL Microscopy, Fluorescence Phosphorylation Proto-Oncogene Proteins c-akt Tropomodulin Lim, C.-Y Bi, X Wu, D Kim, J.B Gunning, P.W Hong, W Han, W Tropomodulin3 is a novel Akt2 effector regulating insulin-stimulated GLUT4 exocytosis through cortical actin remodeling
description	10.1038/ncomms6951
author2	INSTITUTE OF MOLECULAR & CELL BIOLOGY
author_facet	INSTITUTE OF MOLECULAR & CELL BIOLOGY Lim, C.-Y Bi, X Wu, D Kim, J.B Gunning, P.W Hong, W Han, W
format	Article
author	Lim, C.-Y Bi, X Wu, D Kim, J.B Gunning, P.W Hong, W Han, W
author_sort	Lim, C.-Y
title	Tropomodulin3 is a novel Akt2 effector regulating insulin-stimulated GLUT4 exocytosis through cortical actin remodeling
title_short	Tropomodulin3 is a novel Akt2 effector regulating insulin-stimulated GLUT4 exocytosis through cortical actin remodeling
title_full	Tropomodulin3 is a novel Akt2 effector regulating insulin-stimulated GLUT4 exocytosis through cortical actin remodeling
title_fullStr	Tropomodulin3 is a novel Akt2 effector regulating insulin-stimulated GLUT4 exocytosis through cortical actin remodeling
title_full_unstemmed	Tropomodulin3 is a novel Akt2 effector regulating insulin-stimulated GLUT4 exocytosis through cortical actin remodeling
title_sort	tropomodulin3 is a novel akt2 effector regulating insulin-stimulated glut4 exocytosis through cortical actin remodeling
publisher	Nature Publishing Group
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/180482
_version_	1779152701832036352

Tropomodulin3 is a novel Akt2 effector regulating insulin-stimulated GLUT4 exocytosis through cortical actin remodeling

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