Artemin is hypoxia responsive and promotes oncogenicity and increased tumor initiating capacity in hepatocellular carcinoma

10.18632/oncotarget.6572

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Main Authors:	Zhang, M, Zhang, W, Wu, Z, Liu, S, Sun, L, Zhong, Y, Zhang, X, Kong, X, Qian, P, Zhang, H, Lobie, P.E, Zhu, T
Other Authors:	DEPT OF PHARMACOLOGY
Format:	Article
Published:	2020
Subjects:	artemin CD133 antigen hypoxia inducible factor 1alpha protein kinase B ARTN protein, human HIF1A protein, human messenger RNA nerve protein apoptosis Article cancer growth cancer stem cell cancer survival carcinogenicity cell expansion cell hypoxia cell motility cell population cell proliferation controlled study epithelial mesenchymal transition human human cell in vitro study in vivo study liver cell carcinoma protein targeting signal transduction tumor invasion tumor volume animal Bagg albino mouse cell transformation drug screening enzyme immunoassay fluorescent antibody technique genetics hypoxia liver tumor male metabolism mouse nude mouse pathology pathophysiology prognosis real time polymerase chain reaction reverse transcription polymerase chain reaction tumor cell culture Animals Apoptosis Carcinoma, Hepatocellular Cell Proliferation Cell Transformation, Neoplastic Epithelial-Mesenchymal Transition Fluorescent Antibody Technique Humans Hypoxia Hypoxia-Inducible Factor 1, alpha Subunit Immunoenzyme Techniques Liver Neoplasms Male Mice Mice, Inbred BALB C Mice, Nude Neoplastic Stem Cells Nerve Tissue Proteins Prognosis Real-Time Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger Tumor Cells, Cultured Xenograft Model Antitumor Assays
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/180860
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1808602023-10-31T21:19:36Z Artemin is hypoxia responsive and promotes oncogenicity and increased tumor initiating capacity in hepatocellular carcinoma Zhang, M Zhang, W Wu, Z Liu, S Sun, L Zhong, Y Zhang, X Kong, X Qian, P Zhang, H Lobie, P.E Zhu, T DEPT OF PHARMACOLOGY artemin CD133 antigen hypoxia inducible factor 1alpha protein kinase B ARTN protein, human HIF1A protein, human hypoxia inducible factor 1alpha messenger RNA nerve protein apoptosis Article cancer growth cancer stem cell cancer survival carcinogenicity cell expansion cell hypoxia cell motility cell population cell proliferation controlled study epithelial mesenchymal transition human human cell in vitro study in vivo study liver cell carcinoma protein targeting signal transduction tumor invasion tumor volume animal Bagg albino mouse cell transformation drug screening enzyme immunoassay epithelial mesenchymal transition fluorescent antibody technique genetics hypoxia liver cell carcinoma liver tumor male metabolism mouse nude mouse pathology pathophysiology prognosis real time polymerase chain reaction reverse transcription polymerase chain reaction tumor cell culture Animals Apoptosis Carcinoma, Hepatocellular Cell Proliferation Cell Transformation, Neoplastic Epithelial-Mesenchymal Transition Fluorescent Antibody Technique Humans Hypoxia Hypoxia-Inducible Factor 1, alpha Subunit Immunoenzyme Techniques Liver Neoplasms Male Mice Mice, Inbred BALB C Mice, Nude Neoplastic Stem Cells Nerve Tissue Proteins Prognosis Real-Time Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger Tumor Cells, Cultured Xenograft Model Antitumor Assays 10.18632/oncotarget.6572 Oncotarget 7 3 3267-3282 2020-10-27T05:29:09Z 2020-10-27T05:29:09Z 2016 Article Zhang, M, Zhang, W, Wu, Z, Liu, S, Sun, L, Zhong, Y, Zhang, X, Kong, X, Qian, P, Zhang, H, Lobie, P.E, Zhu, T (2016). Artemin is hypoxia responsive and promotes oncogenicity and increased tumor initiating capacity in hepatocellular carcinoma. Oncotarget 7 (3) : 3267-3282. ScholarBank@NUS Repository. https://doi.org/10.18632/oncotarget.6572 19492553 https://scholarbank.nus.edu.sg/handle/10635/180860 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	artemin CD133 antigen hypoxia inducible factor 1alpha protein kinase B ARTN protein, human HIF1A protein, human hypoxia inducible factor 1alpha messenger RNA nerve protein apoptosis Article cancer growth cancer stem cell cancer survival carcinogenicity cell expansion cell hypoxia cell motility cell population cell proliferation controlled study epithelial mesenchymal transition human human cell in vitro study in vivo study liver cell carcinoma protein targeting signal transduction tumor invasion tumor volume animal Bagg albino mouse cell transformation drug screening enzyme immunoassay epithelial mesenchymal transition fluorescent antibody technique genetics hypoxia liver cell carcinoma liver tumor male metabolism mouse nude mouse pathology pathophysiology prognosis real time polymerase chain reaction reverse transcription polymerase chain reaction tumor cell culture Animals Apoptosis Carcinoma, Hepatocellular Cell Proliferation Cell Transformation, Neoplastic Epithelial-Mesenchymal Transition Fluorescent Antibody Technique Humans Hypoxia Hypoxia-Inducible Factor 1, alpha Subunit Immunoenzyme Techniques Liver Neoplasms Male Mice Mice, Inbred BALB C Mice, Nude Neoplastic Stem Cells Nerve Tissue Proteins Prognosis Real-Time Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger Tumor Cells, Cultured Xenograft Model Antitumor Assays
spellingShingle	artemin CD133 antigen hypoxia inducible factor 1alpha protein kinase B ARTN protein, human HIF1A protein, human hypoxia inducible factor 1alpha messenger RNA nerve protein apoptosis Article cancer growth cancer stem cell cancer survival carcinogenicity cell expansion cell hypoxia cell motility cell population cell proliferation controlled study epithelial mesenchymal transition human human cell in vitro study in vivo study liver cell carcinoma protein targeting signal transduction tumor invasion tumor volume animal Bagg albino mouse cell transformation drug screening enzyme immunoassay epithelial mesenchymal transition fluorescent antibody technique genetics hypoxia liver cell carcinoma liver tumor male metabolism mouse nude mouse pathology pathophysiology prognosis real time polymerase chain reaction reverse transcription polymerase chain reaction tumor cell culture Animals Apoptosis Carcinoma, Hepatocellular Cell Proliferation Cell Transformation, Neoplastic Epithelial-Mesenchymal Transition Fluorescent Antibody Technique Humans Hypoxia Hypoxia-Inducible Factor 1, alpha Subunit Immunoenzyme Techniques Liver Neoplasms Male Mice Mice, Inbred BALB C Mice, Nude Neoplastic Stem Cells Nerve Tissue Proteins Prognosis Real-Time Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger Tumor Cells, Cultured Xenograft Model Antitumor Assays Zhang, M Zhang, W Wu, Z Liu, S Sun, L Zhong, Y Zhang, X Kong, X Qian, P Zhang, H Lobie, P.E Zhu, T Artemin is hypoxia responsive and promotes oncogenicity and increased tumor initiating capacity in hepatocellular carcinoma
description	10.18632/oncotarget.6572
author2	DEPT OF PHARMACOLOGY
author_facet	DEPT OF PHARMACOLOGY Zhang, M Zhang, W Wu, Z Liu, S Sun, L Zhong, Y Zhang, X Kong, X Qian, P Zhang, H Lobie, P.E Zhu, T
format	Article
author	Zhang, M Zhang, W Wu, Z Liu, S Sun, L Zhong, Y Zhang, X Kong, X Qian, P Zhang, H Lobie, P.E Zhu, T
author_sort	Zhang, M
title	Artemin is hypoxia responsive and promotes oncogenicity and increased tumor initiating capacity in hepatocellular carcinoma
title_short	Artemin is hypoxia responsive and promotes oncogenicity and increased tumor initiating capacity in hepatocellular carcinoma
title_full	Artemin is hypoxia responsive and promotes oncogenicity and increased tumor initiating capacity in hepatocellular carcinoma
title_fullStr	Artemin is hypoxia responsive and promotes oncogenicity and increased tumor initiating capacity in hepatocellular carcinoma
title_full_unstemmed	Artemin is hypoxia responsive and promotes oncogenicity and increased tumor initiating capacity in hepatocellular carcinoma
title_sort	artemin is hypoxia responsive and promotes oncogenicity and increased tumor initiating capacity in hepatocellular carcinoma
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/180860
_version_	1781792402521980928

Artemin is hypoxia responsive and promotes oncogenicity and increased tumor initiating capacity in hepatocellular carcinoma

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