Antitumor activity of the multikinase inhibitor regorafenib in patient-derived xenograft models of gastric cancer

• Main Authors: Huynh, H, Ong, R, Zopf, D
• Other Authors: MEDICINE
• Format: Article
• Published: 2020
• Subjects: regorafenib; angiogenesis inhibitor; antineoplastic agent; carbanilamide derivative; protein kinase inhibitor; pyridine derivative; angiogenesis; animal experiment; animal model; animal tissue; antineoplastic activity; apoptosis; Article; cancer inhibition; cell proliferation; controlled study; drug efficacy; drug tolerability; human; in vivo study; male; mouse; nonhuman; priority journal; signal transduction; stomach cancer; treatment response; tumor volume; animal; disease model; dose response; drug effects; drug screening; Neovascularization, Pathologic; pathology; Stomach Neoplasms; tumor cell line; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Mice; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Tumor Burden; Xenograft Model Antitumor Assays
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/180879
• Institution: National University of Singapore

10.1186/s13046-015-0243-5