Blocking the PI3K/AKT pathway enhances mammalian reovirus replication by repressing IFN-stimulated genes

10.3389/fmicb.2015.00886

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Main Authors:	Tian, J, Zhang, X, Wu, H, Liu, C, Li, Z, Hu, X, Su, S, Wang, L.-F, Qu, L
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	2020
Subjects:	chlorpromazine clathrin focal adhesion kinase Gab1 protein genistein interferon membrane protein phosphatidylinositol 3 kinase protein kinase B protein p85 small interfering RNA unclassified drug wortmannin Article caveola controlled study down regulation endocytosis enzyme linked immunosorbent assay gene gene expression human human cell in vitro study interferon gene intracellular signaling luciferase assay molecular cloning nonhuman phylogeny protein phosphorylation real time polymerase chain reaction Reoviridae reovirus infection reverse transcription polymerase chain reaction RNA synthesis serotype upregulation virion virus inactivation virus replication Western blotting
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/180930
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1809302023-11-01T07:42:37Z Blocking the PI3K/AKT pathway enhances mammalian reovirus replication by repressing IFN-stimulated genes Tian, J Zhang, X Wu, H Liu, C Li, Z Hu, X Su, S Wang, L.-F Qu, L DUKE-NUS MEDICAL SCHOOL chlorpromazine clathrin focal adhesion kinase Gab1 protein genistein interferon membrane protein phosphatidylinositol 3 kinase protein kinase B protein p85 small interfering RNA unclassified drug wortmannin Article caveola controlled study down regulation endocytosis enzyme linked immunosorbent assay gene gene expression human human cell in vitro study interferon gene intracellular signaling luciferase assay molecular cloning nonhuman phylogeny protein phosphorylation real time polymerase chain reaction Reoviridae reovirus infection reverse transcription polymerase chain reaction RNA synthesis serotype upregulation virion virus inactivation virus replication Western blotting 10.3389/fmicb.2015.00886 Frontiers in Microbiology 6 SEP 886 2020-10-27T05:44:56Z 2020-10-27T05:44:56Z 2015 Article Tian, J, Zhang, X, Wu, H, Liu, C, Li, Z, Hu, X, Su, S, Wang, L.-F, Qu, L (2015). Blocking the PI3K/AKT pathway enhances mammalian reovirus replication by repressing IFN-stimulated genes. Frontiers in Microbiology 6 (SEP) : 886. ScholarBank@NUS Repository. https://doi.org/10.3389/fmicb.2015.00886 1664302X https://scholarbank.nus.edu.sg/handle/10635/180930 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	chlorpromazine clathrin focal adhesion kinase Gab1 protein genistein interferon membrane protein phosphatidylinositol 3 kinase protein kinase B protein p85 small interfering RNA unclassified drug wortmannin Article caveola controlled study down regulation endocytosis enzyme linked immunosorbent assay gene gene expression human human cell in vitro study interferon gene intracellular signaling luciferase assay molecular cloning nonhuman phylogeny protein phosphorylation real time polymerase chain reaction Reoviridae reovirus infection reverse transcription polymerase chain reaction RNA synthesis serotype upregulation virion virus inactivation virus replication Western blotting
spellingShingle	chlorpromazine clathrin focal adhesion kinase Gab1 protein genistein interferon membrane protein phosphatidylinositol 3 kinase protein kinase B protein p85 small interfering RNA unclassified drug wortmannin Article caveola controlled study down regulation endocytosis enzyme linked immunosorbent assay gene gene expression human human cell in vitro study interferon gene intracellular signaling luciferase assay molecular cloning nonhuman phylogeny protein phosphorylation real time polymerase chain reaction Reoviridae reovirus infection reverse transcription polymerase chain reaction RNA synthesis serotype upregulation virion virus inactivation virus replication Western blotting Tian, J Zhang, X Wu, H Liu, C Li, Z Hu, X Su, S Wang, L.-F Qu, L Blocking the PI3K/AKT pathway enhances mammalian reovirus replication by repressing IFN-stimulated genes
description	10.3389/fmicb.2015.00886
author2	DUKE-NUS MEDICAL SCHOOL
author_facet	DUKE-NUS MEDICAL SCHOOL Tian, J Zhang, X Wu, H Liu, C Li, Z Hu, X Su, S Wang, L.-F Qu, L
format	Article
author	Tian, J Zhang, X Wu, H Liu, C Li, Z Hu, X Su, S Wang, L.-F Qu, L
author_sort	Tian, J
title	Blocking the PI3K/AKT pathway enhances mammalian reovirus replication by repressing IFN-stimulated genes
title_short	Blocking the PI3K/AKT pathway enhances mammalian reovirus replication by repressing IFN-stimulated genes
title_full	Blocking the PI3K/AKT pathway enhances mammalian reovirus replication by repressing IFN-stimulated genes
title_fullStr	Blocking the PI3K/AKT pathway enhances mammalian reovirus replication by repressing IFN-stimulated genes
title_full_unstemmed	Blocking the PI3K/AKT pathway enhances mammalian reovirus replication by repressing IFN-stimulated genes
title_sort	blocking the pi3k/akt pathway enhances mammalian reovirus replication by repressing ifn-stimulated genes
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/180930
_version_	1781792419302342656

Blocking the PI3K/AKT pathway enhances mammalian reovirus replication by repressing IFN-stimulated genes

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