5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair

• المؤلفون الرئيسيون: Srinivas, U.S, Dyczkowski, J, Beißbarth, T, Gaedcke, J, Mansour, W.Y, Borgmann, K, Dobbelstein, M
• مؤلفون آخرون: CANCER SCIENCE INSTITUTE OF SINGAPORE
• التنسيق: مقال
• منشور في: 2020
• الموضوعات: BRCA2 protein; double stranded DNA; fluorouracil; histone H2AX; Rad51 protein; zinostatin; antineoplastic agent; Article; cell proliferation; colorectal cancer cell line; controlled study; DNA synthesis; double stranded DNA break; drug efficacy; human; human cell; human tissue; protein targeting; recombination repair; upregulation; chemoradiotherapy; Colorectal Neoplasms; confocal microscopy; DNA microarray; drug effects; flow cytometry; fluorescence microscopy; genetics; immunoblotting; reverse transcription polymerase chain reaction; tumor cell line; Antineoplastic Agents; Cell Line, Tumor; Chemoradiotherapy; DNA Breaks, Double-Stranded; Flow Cytometry; Fluorouracil; Humans; Immunoblotting; Microscopy, Confocal; Microscopy, Fluorescence; Oligonucleotide Array Sequence Analysis; Recombinational DNA Repair; Reverse Transcriptase Polymerase Chain Reaction
• الوصول للمادة أونلاين: https://scholarbank.nus.edu.sg/handle/10635/180952
• المؤسسة: National University of Singapore

10.18632/oncotarget.3728