5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair
10.18632/oncotarget.3728
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Published: |
2020
|
| Subjects: | |
| Online Access: | https://scholarbank.nus.edu.sg/handle/10635/180952 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Institution: | National University of Singapore |
| id |
sg-nus-scholar.10635-180952 |
|---|---|
| record_format |
dspace |
| spelling |
sg-nus-scholar.10635-1809522024-11-09T18:25:19Z 5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair Srinivas, U.S Dyczkowski, J Beißbarth, T Gaedcke, J Mansour, W.Y Borgmann, K Dobbelstein, M CANCER SCIENCE INSTITUTE OF SINGAPORE BRCA2 protein double stranded DNA fluorouracil histone H2AX Rad51 protein zinostatin antineoplastic agent fluorouracil Article cell proliferation colorectal cancer cell line controlled study DNA synthesis double stranded DNA break drug efficacy human human cell human tissue protein targeting recombination repair upregulation chemoradiotherapy Colorectal Neoplasms confocal microscopy DNA microarray double stranded DNA break drug effects flow cytometry fluorescence microscopy genetics immunoblotting recombination repair reverse transcription polymerase chain reaction tumor cell line Antineoplastic Agents Cell Line, Tumor Chemoradiotherapy Colorectal Neoplasms DNA Breaks, Double-Stranded Flow Cytometry Fluorouracil Humans Immunoblotting Microscopy, Confocal Microscopy, Fluorescence Oligonucleotide Array Sequence Analysis Recombinational DNA Repair Reverse Transcriptase Polymerase Chain Reaction 10.18632/oncotarget.3728 Oncotarget 6 14 12574-12586 2020-10-27T05:50:44Z 2020-10-27T05:50:44Z 2015 Article Srinivas, U.S, Dyczkowski, J, Beißbarth, T, Gaedcke, J, Mansour, W.Y, Borgmann, K, Dobbelstein, M (2015). 5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair. Oncotarget 6 (14) : 12574-12586. ScholarBank@NUS Repository. https://doi.org/10.18632/oncotarget.3728 19492553 https://scholarbank.nus.edu.sg/handle/10635/180952 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031 |
| institution |
National University of Singapore |
| building |
NUS Library |
| continent |
Asia |
| country |
Singapore Singapore |
| content_provider |
NUS Library |
| collection |
ScholarBank@NUS |
| topic |
BRCA2 protein double stranded DNA fluorouracil histone H2AX Rad51 protein zinostatin antineoplastic agent fluorouracil Article cell proliferation colorectal cancer cell line controlled study DNA synthesis double stranded DNA break drug efficacy human human cell human tissue protein targeting recombination repair upregulation chemoradiotherapy Colorectal Neoplasms confocal microscopy DNA microarray double stranded DNA break drug effects flow cytometry fluorescence microscopy genetics immunoblotting recombination repair reverse transcription polymerase chain reaction tumor cell line Antineoplastic Agents Cell Line, Tumor Chemoradiotherapy Colorectal Neoplasms DNA Breaks, Double-Stranded Flow Cytometry Fluorouracil Humans Immunoblotting Microscopy, Confocal Microscopy, Fluorescence Oligonucleotide Array Sequence Analysis Recombinational DNA Repair Reverse Transcriptase Polymerase Chain Reaction |
| spellingShingle |
BRCA2 protein double stranded DNA fluorouracil histone H2AX Rad51 protein zinostatin antineoplastic agent fluorouracil Article cell proliferation colorectal cancer cell line controlled study DNA synthesis double stranded DNA break drug efficacy human human cell human tissue protein targeting recombination repair upregulation chemoradiotherapy Colorectal Neoplasms confocal microscopy DNA microarray double stranded DNA break drug effects flow cytometry fluorescence microscopy genetics immunoblotting recombination repair reverse transcription polymerase chain reaction tumor cell line Antineoplastic Agents Cell Line, Tumor Chemoradiotherapy Colorectal Neoplasms DNA Breaks, Double-Stranded Flow Cytometry Fluorouracil Humans Immunoblotting Microscopy, Confocal Microscopy, Fluorescence Oligonucleotide Array Sequence Analysis Recombinational DNA Repair Reverse Transcriptase Polymerase Chain Reaction Srinivas, U.S Dyczkowski, J Beißbarth, T Gaedcke, J Mansour, W.Y Borgmann, K Dobbelstein, M 5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair |
| description |
10.18632/oncotarget.3728 |
| author2 |
CANCER SCIENCE INSTITUTE OF SINGAPORE |
| author_facet |
CANCER SCIENCE INSTITUTE OF SINGAPORE Srinivas, U.S Dyczkowski, J Beißbarth, T Gaedcke, J Mansour, W.Y Borgmann, K Dobbelstein, M |
| format |
Article |
| author |
Srinivas, U.S Dyczkowski, J Beißbarth, T Gaedcke, J Mansour, W.Y Borgmann, K Dobbelstein, M |
| author_sort |
Srinivas, U.S |
| title |
5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair |
| title_short |
5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair |
| title_full |
5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair |
| title_fullStr |
5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair |
| title_full_unstemmed |
5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair |
| title_sort |
5-fluorouracil sensitizes colorectal tumor cells towards double stranded dna breaks by interfering with homologous recombination repair |
| publishDate |
2020 |
| url |
https://scholarbank.nus.edu.sg/handle/10635/180952 |
| _version_ |
1821227272136294400 |