Administration of PDE4 inhibitors suppressed the pannus-like inflammation by inhibition of cytokine production by macrophages and synovial fibroblast proliferation
10.1155/2007/58901
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sg-nus-scholar.10635-1810292024-04-24T05:51:35Z Administration of PDE4 inhibitors suppressed the pannus-like inflammation by inhibition of cytokine production by macrophages and synovial fibroblast proliferation Kobayashi, K Suda, T Manabe, H Miki, I MEDICINE bovine serum albumin cilomilast diclofenac hydroxyproline interleukin 12 interleukin 1beta kf 66490 leflunomide lipopolysaccharide methotrexate myeloperoxidase phosphodiesterase IV inhibitor prednisolone thioglycolic acid tumor necrosis factor alpha unclassified drug cytokine phosphodiesterase IV animal experiment animal model animal tissue article cell proliferation controlled study cytokine production drug mechanism enzyme activity granuloma inflammation macrophage male mouse nonhuman priority journal rheumatoid arthritis animal Bagg albino mouse drug antagonism fibroblast inflammation macrophage metabolism oral drug administration subcutaneous drug administration synovium Animalia Bovinae Murinae Mus Rattus Administration, Oral Animals Arthritis, Rheumatoid Cell Proliferation Cyclic Nucleotide Phosphodiesterases, Type 4 Cytokines Fibroblasts Inflammation Injections, Subcutaneous Macrophages Male Mice Mice, Inbred BALB C Serum Albumin, Bovine Synovial Membrane 10.1155/2007/58901 Mediators of Inflammation 2007 58901 2020-10-27T06:57:34Z 2020-10-27T06:57:34Z 2007 Article Kobayashi, K, Suda, T, Manabe, H, Miki, I (2007). Administration of PDE4 inhibitors suppressed the pannus-like inflammation by inhibition of cytokine production by macrophages and synovial fibroblast proliferation. Mediators of Inflammation 2007 : 58901. ScholarBank@NUS Repository. https://doi.org/10.1155/2007/58901 0962-9351 https://scholarbank.nus.edu.sg/handle/10635/181029 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031 |
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bovine serum albumin cilomilast diclofenac hydroxyproline interleukin 12 interleukin 1beta kf 66490 leflunomide lipopolysaccharide methotrexate myeloperoxidase phosphodiesterase IV inhibitor prednisolone thioglycolic acid tumor necrosis factor alpha unclassified drug cytokine phosphodiesterase IV animal experiment animal model animal tissue article cell proliferation controlled study cytokine production drug mechanism enzyme activity granuloma inflammation macrophage male mouse nonhuman priority journal rheumatoid arthritis animal Bagg albino mouse drug antagonism fibroblast inflammation macrophage metabolism oral drug administration subcutaneous drug administration synovium Animalia Bovinae Murinae Mus Rattus Administration, Oral Animals Arthritis, Rheumatoid Cell Proliferation Cyclic Nucleotide Phosphodiesterases, Type 4 Cytokines Fibroblasts Inflammation Injections, Subcutaneous Macrophages Male Mice Mice, Inbred BALB C Serum Albumin, Bovine Synovial Membrane |
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bovine serum albumin cilomilast diclofenac hydroxyproline interleukin 12 interleukin 1beta kf 66490 leflunomide lipopolysaccharide methotrexate myeloperoxidase phosphodiesterase IV inhibitor prednisolone thioglycolic acid tumor necrosis factor alpha unclassified drug cytokine phosphodiesterase IV animal experiment animal model animal tissue article cell proliferation controlled study cytokine production drug mechanism enzyme activity granuloma inflammation macrophage male mouse nonhuman priority journal rheumatoid arthritis animal Bagg albino mouse drug antagonism fibroblast inflammation macrophage metabolism oral drug administration subcutaneous drug administration synovium Animalia Bovinae Murinae Mus Rattus Administration, Oral Animals Arthritis, Rheumatoid Cell Proliferation Cyclic Nucleotide Phosphodiesterases, Type 4 Cytokines Fibroblasts Inflammation Injections, Subcutaneous Macrophages Male Mice Mice, Inbred BALB C Serum Albumin, Bovine Synovial Membrane Kobayashi, K Suda, T Manabe, H Miki, I Administration of PDE4 inhibitors suppressed the pannus-like inflammation by inhibition of cytokine production by macrophages and synovial fibroblast proliferation |
description |
10.1155/2007/58901 |
author2 |
MEDICINE |
author_facet |
MEDICINE Kobayashi, K Suda, T Manabe, H Miki, I |
format |
Article |
author |
Kobayashi, K Suda, T Manabe, H Miki, I |
author_sort |
Kobayashi, K |
title |
Administration of PDE4 inhibitors suppressed the pannus-like inflammation by inhibition of cytokine production by macrophages and synovial fibroblast proliferation |
title_short |
Administration of PDE4 inhibitors suppressed the pannus-like inflammation by inhibition of cytokine production by macrophages and synovial fibroblast proliferation |
title_full |
Administration of PDE4 inhibitors suppressed the pannus-like inflammation by inhibition of cytokine production by macrophages and synovial fibroblast proliferation |
title_fullStr |
Administration of PDE4 inhibitors suppressed the pannus-like inflammation by inhibition of cytokine production by macrophages and synovial fibroblast proliferation |
title_full_unstemmed |
Administration of PDE4 inhibitors suppressed the pannus-like inflammation by inhibition of cytokine production by macrophages and synovial fibroblast proliferation |
title_sort |
administration of pde4 inhibitors suppressed the pannus-like inflammation by inhibition of cytokine production by macrophages and synovial fibroblast proliferation |
publishDate |
2020 |
url |
https://scholarbank.nus.edu.sg/handle/10635/181029 |
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1800914621400350720 |